Results 31 to 40 of about 114,909 (286)

Clinical Characteristics and Outcome of MDR/XDR Bacterial Infections in a Neuromuscular Semi-Intensive/Sub-Intensive Care Unit

Antibiotics, 2022
(1) Background: The aim of this study was to assess the clinical and microbiological characteristics of multidrug-resistant infections in a neuromuscular semi-intensive/sub-intensive care unit; (2) Methods: Retrospective analysis on data from 18 patients
Arta Karruli, Alessia Massa, Lorenzo Bertolino, Roberto Andini, Pasquale Sansone, Salvatore Dongiovanni, Maria Caterina Pace, Vincenzo Pota, Emanuele Durante-Mangoni   +8 more
doaj   +1 more source

The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]

, 2008
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé, A Baslé, A Bryskier, A Davin-Regli, A Davin-Régli, A Doménech-Sánchez, A Doménech-Sánchez, A Loli, A Mena, A Mena, A Prilipov, A Thiolas, A Thiolas, AA Medeiros, AH Delcour, AM Berezhkovskii, AM Giuliodori, AS Low, C Bornet, C Bornet, C Bosi, C Danelon, C Danelon, C Rodrigues, C Sheridan, Chloë E. James, D Jeanteur, D Szabó, DJ Wolter, E Dé, E Elliott, E Sugawara, EM Nestorovich, EM Nestorovich, F Yoshimura, FM Kaczmarek, G Schwarz, GA Jacoby, GE Schulz, H Nikaido, H Nikaido, H Nikaido, H Samartzidou, H Samartzidou, J Bredin, J Chevalier, J Chevalier, J-M Pagès, JC Cai, Jean-Marie Pagès, JM Bower, K Poole, L Kullman, L Martínez-Martínez, LB Rice, LJ Piddock, LP Randall, M Ceccarelli, M Guillier, M Luckey, M Malléa, M Olesky, M Olesky, M Viveiros, MA Kohanski, Mathias Winterhalter, MM Ochs, N El Amin, P Valentin-Hansen, R Dutzler, R Iyer, R Iyer, R Koebnik, RE Hancock, RN Charrel, S Biswas, S Blot, S Hernández-Allés, S Hernández-Allés, S Nekolla, S Vidal, S Vidal, SF Epp, SM Bezrukov, SM Bezrukov, SR Norrby, SW Cowan, T Ferenci, T Mach, UO Hasdemir, V Simonet, V Simonet, WL Veal, WM Shafer, WR Bauer, XZ Li   +95 more
core   +1 more source

A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options

Future Science OA, 2020
Carbapenems are a class of antimicrobial agents reserved for infections caused by multidrug-resistant microorganisms. The emergence of carbapenem resistance has become a serious public health threat.
Ann A Elshamy, Khaled M Aboshanab
doaj   +1 more source

Genomic Features Associated with the Degree of Phenotypic Resistance to Carbapenems in Carbapenem-Resistant Klebsiella pneumoniae

mSystems, 2021
Carbapenem-resistant Klebsiella pneumoniae strains cause severe infections that are difficult to treat. The production of carbapenemases such as the K.
Zackery P. Bulman, Fiorella Krapp, Nathan B. Pincus, Eric Wenzler, Katherine R. Murphy, Chao Qi, Egon A. Ozer, Alan R. Hauser   +7 more
doaj   +1 more source

A blaVIM-2 Plasmid Disseminating in Extensively Drug-Resistant Clinical Pseudomonas aeruginosa and Serratia marcescens Isolates [PDF]

, 2014
Infections caused by carbapenem-resistant Enterobacteriaceae isolates are an issue of major global concern (1). Genes coding for metallo-β-lactamases (MβLs) identified in clinical isolates are associated with mobile elements and subject to horizontal ...
Centron, Daniela, Deraspe, Maxime, Famiglietti, Angela María Rosa, Kovensky, Jaime, Pistorio, Mariano, Quiroga, Cecilia, Raymond, Frédéric, Rodriguez, Hernan Bernardo, Roy, Paul H., Vilacoba, Elisabet   +9 more
core   +2 more sources

Carbapenem resistance in Canada [PDF]

Canadian Medical Association Journal, 2009
For more than 2 decades, carbapenems have been considered the pharmacotherapy of last resort for managing multidrug-resistant infections caused by Enterobacteriaceae bacteria (e.g., Escherichia coli and Salmonella ).
Baldwin, Toye, Sigmund, Krajden, Milan, Fuksa, Donald E, Low, Dylan R, Pillai   +4 more
openaire   +2 more sources

Carbapenem-resistant Pseudomonas aeruginosa outbreak in an intensive care unit of a teaching hospital

Brazilian Journal of Infectious Diseases
The genetic similarity of carbapenem-resistant Pseudomonas aeruginosa strains isolated in the Hospital Universitário São Francisco, Bragança Paulista, São Paulo, Brasil, was evaluated by pulsed field gel electrophoresis (PFGE).
Ana C. Gales, Patrícia L. Torres, Dominique S. O. Vilarinho, Renata S. Melo, Claudinéia F. L. Silva, Rosângela F. Cereda   +5 more
doaj   +1 more source

Wild Nutria (Myocastor coypus) Is a Potential Reservoir of Carbapenem-Resistant and Zoonotic Aeromonas spp. in Korea

Microorganisms, 2019
The emergence and spread of antibiotic-resistant Aeromonas spp. is a serious public and animal health concern. Wild animals serve as reservoirs, vectors, and sentinels of these bacteria and can facilitate their transmission to humans and livestock.
Se Ra Lim, Do-Hun Lee, Seon Young Park, Seungki Lee, Hyo Yeon Kim, Moo-Seung Lee, Jung Ro Lee, Jee Eun Han, Hye Kwon Kim, Ji Hyung Kim   +9 more
doaj   +1 more source

Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]

, 2015
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC, Bourigault, C, Holmes, A, Iucet, JC, Lepelletier, D, Moore, L, Vella, V   +6 more
core   +1 more source

Restoring carbapenem efficacy: a novel carbapenem companion targeting metallo-β-lactamases in carbapenem-resistant Enterobacterales

Journal of Antimicrobial Chemotherapy, 2020
AbstractBackgroundThe dissemination of MBLs compromises effective use of many β-lactams in the treatment of patients with life-threatening bacterial infections. Predicted global increases in the prevalence of MBL-producing carbapenem-resistant Enterobacterales (CRE) are being realized, yielding infections that are untreatable with existing therapies ...
Nicola Ooi, Victoria E Lee, Nathan Chalam-Judge, Rebecca Newman, Andrew J Wilkinson, Ian R Cooper, David Orr, Sally Lee, Victoria J Savage   +8 more
openaire   +3 more sources