Results 81 to 90 of about 11,730,789 (176)

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

A comparison of phenotypic methods for the detection of carbapenemase in Klebsiella pneumoniae

Journal of Infection in Developing Countries
Introduction: Carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates are increasingly spreading in the community and pose a serious public health threat. Rapid and accurate detection of these isolates is therefore critical.
Betül Günaydın, Nuri Kiraz
doaj   +1 more source

The Boron–Neuron Connection: The Potential of Boron‐Containing Molecules for Treating Incurable Amyotrophic Lateral Sclerosis

ChemMedChem, Volume 21, Issue 21, 12 November 2026.
Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai, Billy Vuong, Muhammad Shaharyar K. Afridi, Sasha Leggett, Hemin Roghzai, Geoffrey K. Tranmer   +5 more
wiley   +1 more source

Evaluation of the carbapenem inactivation method for detection of carbapenemase-producing gram-negative bacteria in comparison with the RAPIDEC CARBA NP [PDF]

, 2016
SANDALLI, Cemal/0000-0002-1298-3687; aktas, elif/0000-0003-3087-5425Timely detection of carbapenemases by both phenotypic and genotypic methods is essential for developing strategies to control the spread of infections by carbapenem-resistant isolates ...
Otlu, Barış, Kulah, Canan, Bulut, Mehmet Emin, Cömert, Füsun, Erdemir, Duygu, Çiçek, Ayşegül Çopur, Gürsoy, Nafia Canan, Aktaş, Elif, Sandallı, Cemal, Malkoçoğlu, Gülşah, Otlu, Baris, Çopur Çiçek, Ayşegül, Sandalli, Cemal   +12 more
core   +1 more source

Evaluation of Phenotypic Carbapenemase Production in blaOXA-48 positive K. pneumoniae Isolates by Modified Hodge and Carbapenemase Inactivation Tests

Namık Kemal Tıp Dergisi, 2020
Aim:In recent years, increasing colonization rates of K. pneumoniae in patients with immunosuppression, long hospital stay, invasive devices and treated with broad spectrum antibiotics lead to resistant infections.
Reyhan YİŞ, E. Deniz BAYRAM, Özlem Yüksel ERGİN   +2 more
doaj   +1 more source

Bacterial Agents and Their Multidrug‐Resistance Profile Among Patients Suspected of Bacterial Infections in Hakim Gizaw Hospital, Debre Berhan, Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Antimicrobial resistance is a global threat. Bacteria showed higher resistance in Ethiopia, and up‐to‐date data on it is urgently required for effective interventions. This study aimed to determine occurrence of multi‐drug‐resistant (MDR) bacterial isolates among patients presented to Hakim Gizaw Hospital (HGH).
Tizazu Zenebe Zelelie, Ermias Endewunetu, Yosef Temesgen, Demissew Shenkute Gebreyes, Zenawork Sahile, Biniam Mekonnen, Getachew Bizuneh, Asrat Berihun, Berhanu Yitayew   +8 more
wiley   +1 more source

Evaluation of Carbapenem Inactivation Method for the Identifi cation of Carbapenemase-Producing Enterobacteriaceae Strains

Mikrobiyoloji Bulteni, 2016
The rapid and accurate identification of carbapenemases is of crucial importance in terms of infection control. Methods employed in the determination of carbapenemases should be constantly updated in the light of technical advances and newly emerging carbapenemase variants.
Gülçin BAYRAMOĞLU, Gülşen ULUÇAM, Çiğdem GENÇOĞLU ÖZGÜR   +2 more
openaire   +1 more source

Antimicrobial Resistance in Periodontal Disease: Rethinking Adjunctive Therapy in the Metagenomics Era, the Pressing Need for Precision Treatment and Periodontal Resistome Mapping

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Systemic antibiotics are effective when used as adjunctive therapy in the treatment of periodontitis; however, their use must be balanced against antimicrobial resistance, which is a major threat to global public health. This review provides an expert synthesis of the literature and a field‐level overview of antimicrobial resistance in ...
Meera Alghafri, Lindsey Edwards, David Moyes, Luigi Nibali   +3 more
wiley   +1 more source

ST37 Klebsiella pneumoniae: development of carbapenem resistance in vivo during antimicrobial therapy in neonates

, 2017
Aim: To investigate the mechanism leading to in vivo carbapenem resistance development in Klebsiella pneumoniae. Methods: Carbapenemase was detected using the modified carbapenem inactivation method.
Fang Chen, Wei Cao, Pengling Li, Xiaomeng Xia, Min Yang, Jingjing Tian, Kan Zhang, Aiguo Tang, Rong Zheng, Feihu Hu, Min Wang, Xianping Li, Yixin Xie   +12 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, Volume 600, Issue 19, Page 2947-2960, October 2026.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source