Results 161 to 170 of about 2,236,849 (269)

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Pangenome of Streptomyces sampsonii and Relatives Highlights Horizontal Gene Transfer and Secondary Metabolism in Environmental Adaptation and Ecological Significance

Ecology and Evolution, Volume 16, Issue 9, September 2026.
This study presents a chromosome‐level genome assembly of Streptomyces sampsonii and a pangenome analysis of 95 strains, revealing a highly expansive “open” pangenome. Our results highlight that horizontal gene transfer (HGT) and accessory gene variations drive the evolution of secondary metabolism and environmental adaptation.
Boyang Zhang, Shuo Ji
wiley   +1 more source

Laboratory‐Detected Clostridioides difficile Stool‐Test Positivity and Mortality in Sepsis: A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Sepsis disrupts intestinal microbiota, and broad‐spectrum antibiotics may worsen dysbiosis. Clostridioides difficile (C. difficile) infection (CDI) is a prevalent nosocomial enteric pathogen among critically ill patients, yet its prognostic implications in sepsis remain inadequately studied.
Jiyun Hu, Fuxing Deng, Tingyue Hu, Binbin Meng, Songyun Deng, Lina Zhang, Wenchao Li   +6 more
wiley   +1 more source

Carbapenem-Resistant Enterobacterales in the Western Balkans: Addressing Gaps in European AMR Surveillance Map

In the context of global efforts to combat antimicrobial resistance (AMR), the importance of comprehensive AMR data is more crucial than ever. AMR surveillance networks, such as the European Antimicrobial Resistance Surveillance Network (EARS-Net) and ...
Snezana Brkic, Ivana Cirkovic
core   +1 more source

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

iMetaOmics, Volume 3, Issue 3, September 2026.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos‐Pastén, Gastón Azziz, Rosalba Lagos, Julieta Orlando, Francisco P. Chávez, Andrés E. Marcoleta   +8 more
wiley   +1 more source

Genomic epidemiology of carbapenem resistance in <i>Acinetobacter baumannii</i> in Chile. [PDF]

JAC Antimicrob Resist
Araya-Vega P, Matus-Köhler M, Mardones-Verdugo V, Gómez-Inostroza S, González-Muñoz P, Paredes-Osses E, Roach-Poblete F, González-Rocha G, Opazo-Capurro A.   +8 more
europepmc   +1 more source

Dose Selection for Ceftibuten Combined with Avibactam Tomilopil, a Potential Oral Alternative to Carbapenems for Patients with Complicated Urinary Tract Infections

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract There are currently no oral treatment options for infections caused by extended spectrum β‑lactamase‐producing Enterobacterales. Avibactam tomilopil, a novel oral prodrug of avibactam, is being developed in combination with the oral cephalosporin, ceftibuten, as a potential treatment for patients with complicated urinary tract infections ...
Siddhee A. Sahasrabudhe, Satoshi Shoji, Abhijeet S. Jakate, Bisrat K. Abraham, Sima S. Toussi, Benjamin J. Maligalig, Amanda S. Darekar, Sakambari Tripathy, Constantino Kantaridis, Josue K. Mfopou, Oxana Selivanova, Arthur Bergman, Negar Niki Alami, Ravi Shankar P. Singh   +13 more
wiley   +1 more source

Carbapenem resistance genes and biofilm-virulence uncoupling in <i>Acinetobacter baumannii</i>. [PDF]

Front Antibiot
Tripathi S, Rani K, Berlia R, Sharma A, Hari A, Gaur P, Raj PSS, Raj VS.   +7 more
europepmc   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, Volume 57, Issue 9, Page 1554-1564, September 2026.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Carbapenem Resistance at the Crossroads: A New Therapeutic Era for Critical Care. [PDF]

Indian J Crit Care Med
Prakash J.
europepmc   +1 more source