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The lipoprotein biosynthesis pathway: key to OXA-mediated carbapenem resistance in <i>Acinetobacter baumannii</i>. [PDF]

Antimicrob Agents Chemother
Morán-Barrio J, Giacone L, Brambilla L, Fabbri C, Viale AM.   +4 more
europepmc   +1 more source

Occurrence of Carbapenem Resistance Producing Uropathogens Isolated From Refugees at the Nakivale Settlement in Isingiro District, Uganda: A Cross-Sectional Study. [PDF]

Cureus
Ampaire L, Kabera M, Cherop C, Galimaka W, Nkubi Bagenda C, Tumusiime J, Aggrey B, Okongo B.   +7 more
europepmc   +1 more source

Mechanisms of Action of Carbapenem Resistance

Antibiotics, 2022
Carbapenem antibiotics are the most effective antimicrobials for the treatment of infections caused by the most resistant bacteria. They belong to the category of β-lactams that include the penicillins, cephalosporins, monobactams and carbapenems. This class of antimicrobials has a broader spectrum of activity than most other beta-lactams antibiotics ...
Vincenzo Pota, Caterina Aurílio
exaly   +5 more sources

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Resistance Mechanism of Carbapenem-Resistant Enterobacteriaceae to Quinolones

Clinical Laboratory, 2021
To investigate the epidemics of plasmid-mediated quinolone resistance (PMQR) gene in carbapenem-resistant Enterobacteriaceae (CRE) and the resistance mechanism.We collected CRE bacteria isolated clinically between December 2017 and December 2018 for identification and drug sensitivity testing using a VITEK2 Compact Analyzer.
Ming, Wei, Na, Tu, Kai, Yang
openaire   +2 more sources

Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria

Clinical Infectious Diseases, 2019
Carbapenem resistance in gram-negative bacteria has caused a global epidemic that continues to grow. Although carbapenemase-producing Enterobacteriaceae have received the most attention because resistance was first reported in these pathogens in the ...
Laurent Poirel, Nordmann Patrice
exaly   +2 more sources

The Rise of Carbapenem-Resistant Acinetobacter baumannii

Current Pharmaceutical Design, 2012
Acinetobacter spp. are Gram-negative bacteria that have become one of the most difficult pathogens to treat. The species A. baumannii, largely unknown 30 years ago, has risen to prominence particularly because of its ability to cause infections in immunocompromised patients.
Evans, Benjamin A., Hamouda, Ahmed, Amyes, Sebastian G. B.   +2 more
openaire   +3 more sources

Bacterial Resistance to Carbapenems

1995
The carbapenems have the broadest spectra of all beta-lactams but resistance still occurs, caused by target modification, impermeability or beta-lactamase production. Target modification or replacement is important in methicillin-resistant staphylococci, E. faecium and some pneumococci.
openaire   +2 more sources

[Resistance of enterobacteriaceae to carbapenems].

Klinicka mikrobiologie a infekcni lekarstvi, 2011
Carbapenems are the drugs of choice for the treatment of serious infections caused by ESBL- and AmpC-positive Enterobacteriaceae. An increasing trend of resistance to these antibiotics has been observed recently. The aim of the study was to determine resistance to carbapenems in clinical isolates of the Enterobacteriaceae family and its mechanism ...
M, Htoutou Sedláková, V, Hanulík, M, Chromák, K, Hricovák, M, Senkýřová, M, Kolář   +5 more
openaire   +2 more sources

Options for treating carbapenem-resistant Enterobacteriaceae

Current Opinion in Infectious Diseases, 2014
To address the therapeutic management of carbapenem-resistant Enterobacteriaceae on the basis of literature of the last 12 months.Retrospective and prospective (nonrandomized noncontrolled) studies provide data regarding the management of infections due to carbapenem-resistant Enterobacteriaceae.
Petros I, Rafailidis, Matthew E, Falagas
openaire   +2 more sources