Results 61 to 70 of about 77,949 (280)

Mechanisms of Action of Carbapenem Resistance

Antibiotics, 2022
Carbapenem antibiotics are the most effective antimicrobials for the treatment of infections caused by the most resistant bacteria. They belong to the category of β-lactams that include the penicillins, cephalosporins, monobactams and carbapenems. This class of antimicrobials has a broader spectrum of activity than most other beta-lactams antibiotics ...
Aurilio, Caterina, Sansone, Pasquale, Barbarisi, Manlio, Pota, Vincenzo, Giaccari, Luca Gregorio, Coppolino, Francesco, Barbarisi, Alfonso, Passavanti, Maria Beatrice, Pace, Maria Caterina   +8 more
openaire   +3 more sources

Antibacterial Applications of Black and Violet Phosphorus‐Based Biomaterials

Advanced NanoBiomed Research, EarlyView.
Black and violet phosphorus‐based biomaterials exhibit broad‐spectrum antibacterial efficacy in various infections, including bone, skin, ocular, dental, lung, and sepsis cases. Their antibacterial mechanisms include physical disruption, light‐driven effects, targeted drug delivery, and enhanced composite strategies.
Zhuo Dai, Yu Zhang, Xiaoye Li, Ao He, Qiang Li, Weijun Xiu, Yongbin Mou, Heng Dong, Meng Ding   +8 more
wiley   +1 more source

BlaOXA-48 Genotypic Detection of Carbapenem Resistance in Isolates of Pseudomonas Aeruginosa

Journal of Bahria University Medical and Dental College, 2021
Objective: To determine the prevalence of carbapenem resistance in strains of Pseudomonas aeruginosa at a molecular level by detecting OXA-48 gene which transcribe for resistance to the antibiotic carbapenem among indoor patients of a tertiary care ...
Shaista Bakhat, Yasmeen Taj, Faisal Hanif, Saman Nadeem   +3 more
doaj   +1 more source

Insights into a Novel blaKPC-2-Encoding IncP-6 Plasmid Reveal Carbapenem-Resistance Circulation in Several Enterobacteriaceae Species from Wastewater and a Hospital Source in Spain [PDF]

, 2017
Untreated wastewater, particularly from hospitals and other healthcare facilities, is considered to be a reservoir for multidrug-resistant bacteria.
Cantón, Rafael, Chakraborty, Trinad, Dominguez, Lucas, Falgenhauer, Linda, Imirzalioglu, Can, Lazaro-Perona, Fernando, Mingorance, Jesús, Valverde, Aránzazu, Yao, Yancheng   +8 more
core   +1 more source

Environmental Contamination by Carbapenem-Resistant Enterobacteriaceae [PDF]

Journal of Clinical Microbiology, 2013
ABSTRACT In the last decade, the global emergence of carbapenem resistance in Enterobacteriaceae has posed great concern to public health. Data concerning the role of environmental contamination in the dissemination of carbapenem-resistant Enterobacteriaceae (CRE) are currently ...
Lerner, A., Adler, A., Abu-Hanna, J., Meitus, I., Navon-Venezia, S., Carmeli, Y.   +5 more
openaire   +2 more sources

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Deaths Attributable to Carbapenem-Resistant Enterobacteriaceae Infections

Emerging Infectious Diseases, 2014
We evaluated the number of deaths attributable to carbapenem-resistant Enterobacteriaceae by using studies from around the world published before April 9, 2012.
Matthew E. Falagas, Giannoula S. Tansarli, Drosos E. Karageorgopoulos, Konstantinos Z. Vardakas   +3 more
doaj   +1 more source

Molecular insights of Carbapenem resistance Klebsiella pneumoniae isolates with focus on multidrug resistance from clinical samples

Journal of Infection and Public Health, 2021
Background: Carbapenem are the last-line antibiotic, defence against Gram-negative extended spectrum ß-lactamases producers (ESBLs). Carbapenem resistance Enterobacteriaceae especially Carbapenem resistant-Klebsiella pneumoniae (CR-KP) is recognized as ...
Sureka Indrajith, Asish Kumar Mukhopadhyay, Goutam Chowdhury, Dunia A. Al Farraj, Roua M. Alkufeidy, Sivakumar Natesan, Velmurugan Meghanathan, Selvakumar Gopal, Saravanan Muthupandian   +8 more
doaj   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources