Results 31 to 40 of about 28,072 (215)
The Changing Epidemiology of Carbapenemase-Producing Enterobacterales [PDF]
Rambam Maimonides Medical Journal, 2022 Objective: Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae.
Khetam Hussein +7 more
openaire +3 more sources
Journal of Infection and Public Health, 2017 Summary: Little is known of carbapenemase producing Klebsiella pneumoniae (CPK) in Jordan. This study aimed to determine the prevalence of CPK in a major hospital in Amman, Jordan in 2012–2013 and to characterize the isolates and detect the types of ...
Amin A. Aqel +5 more
doaj +1 more source
The “hidden” carbapenemase of Aeromonas hydrophila [PDF]
Journal of Antimicrobial Chemotherapy, 1996 It has been presumed that there are just two beta-lactamases in the motile Aeromonas species, a carbapenemase and a cephalosporinase, based on the premise that all beta-lactamases can be detected by hydrolysis of the chromogenic cephalosporin, nitrocefin.
M. V. Hayes +2 more
openaire +3 more sources
Annals of Clinical Microbiology and Antimicrobials, 2020 Background Antimicrobial resistance among nosocomial Gram-negative pathogens is a cause for concern in the Asia–Pacific region. The aims of this study were to measure the rates of resistance among clinical isolates collected in Asia–Pacific countries ...
Wen-Chien Ko, Gregory G. Stone
doaj +1 more source
Heliyon, 2023 Carbapenemase enzyme production is responsible for resistance to carbapenem among Gram-negative bacteria. This study aimed to detect common carbapenemase and oxacilinase genes among uropathogenic E.
Mahsa Sadeghi +3 more
doaj +1 more source
, 2019 Carbapenems are usually regarded as the last treatment option for serious infections caused by Gram-negative and Gram-positive microorganisms. Although they are stable to hydrolysis by most β- lactamases, their usage as the last resort antbiotics was seriously compromised by the appearance of carbapenem-hydrolyzing enzymes called carbapenemases.
Bedenić, Branka, Sardelić, Sanda
openaire +2 more sources
Novel Rapid Test for Detecting Carbapenemase [PDF]
Emerging Infectious Diseases, 2020 We developed a carbapenemase test based on the ability of imipenem to inhibit noncarbapenemase β-lactamases. The test uses bacterial isolates with a fluorescent β-lactamase substrate, producing objective results with 100% sensitivity and specificity in 10 minutes. The assay is inexpensive and consists of only 1 mixing step.
Michael Pigula +5 more
openaire +4 more sources
Co-occurrence of Carbapenemase Genes blaNDM, blaVIM, blaKPC and blaOXA-48 in Pseudomonas aeruginosa Clinical Isolates [PDF]
International Journal of Biomedicine, 2023 Pseudomonas aeruginosa, a gram-negative bacterium, is notorious for its innate resistance to many antibiotics. Carbapenems are broad-spectrum antibiotics often used to treat severe P. aeruginosa infections.
Salma Mohamed +6 more
doaj +1 more source
Carbapenemase-producing Enterobacteriaceae in transplant patients
Journal of Antimicrobial Chemotherapy, 2021 Abstract Carbapenemase-producing Enterobacteriaceae (CPE) are a serious public health concern and represent a major threat to immunocompromised hosts, including solid organ (SOT) and stem cell transplant (HSCT) recipients. Transplant patients are at particular risk of developing CPE colonization and/or infection due to their frequent ...
Giannella M. +3 more
openaire +4 more sources
Journal of Pure and Applied Microbiology, 2020 Multidrug resistance has been increasing world wide amongst most microrganisms, and adding to increased rate of both hospital and community acquired infections. Of all resistance mechanisms the alarming spread of carbapenemase producers is most worrisome
Iva Chandola +3 more
doaj +1 more source