Results 41 to 50 of about 28,072 (215)

Overview of Carbapenemase mediated resistance [PDF]

International Journal of Infectious Diseases, 2012
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Spatiotemporal and genomic analysis of carbapenem resistance elements in Enterobacterales from hospital inpatients and natural water ecosystems of an Irish city

Microbiology Spectrum
Carbapenemase-producing Enterobacterales (CPE) is a diverse group of often multidrug-resistant organisms. Surveillance and control of infections are complicated due to the inter-species spread of carbapenemase-encoding genes (CEGs) on mobile genetic ...
Mark Maguire, Carlos Serna, Natalia Montero Serra, Aneta Kovarova, Louise O’Connor, Niamh Cahill, Brigid Hooban, Niall DeLappe, Wendy Brennan, Genevieve Devane, Martin Cormican, Dearbháile Morris, Simone C. Coughlan, Georgios Miliotis, Bruno Gonzalez-Zorn, Liam P. Burke   +15 more
doaj   +1 more source

Carbapenemases in Enterobacteriaceae: the magnitude of a worldwide concern [PDF]

Clinical Microbiology and Infection, 2014
Although carbapenemases in Enterobacteriaceae were relatively rare a decade ago, their emergence and rapid spread is now an alarming worldwide problem, for both the scientific and public health communities [1]. In the present theme issue, we provide an overview of the different factors that probably explain the spread and success of the main ...
Rolain, J. M, CORNAGLIA, Giuseppe
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Klebsiella pneumoniaeCarbapenemase, Canada [PDF]

Emerging Infectious Diseases, 2009
To the Editor: Carbapenems are used to treat life-threatening infections caused by extremely drug-resistant gram-negative pathogens; these drugs represent the last line of defense in the antimicrobial drug armamentarium against serious or invasive infection (1). The rapid global spread of Klebsiella pneumoniae that produces K. pneumoniae carbapenemase (
Milan Fuksa, Dylan R. Pillai, Roberto G. Melano, David J. Farrell, Stephen Lo, Prasad Rawte, Sigmund Krajden, Nathalie Tijet, Nancy Roda   +8 more
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Wide spread of carbapenemase-producing bacterial isolates in a Nigerian environment

Journal of Global Antimicrobial Resistance, 2020
Objectives: The presence of carbapenemase-producing bacterial isolates is found not only in hospital and community settings but also in the environment.
Christophe Le Terrier, Amandine Masseron, Nkolika Stella Uwaezuoke, Chinagozi P. Edwin, Agantem E. Ekuma, Folake Olugbeminiyi, Shuwaram Shettima, Simon Ushie, Laurent Poirel, Patrice Nordmann   +9 more
doaj   +1 more source

Carbapenemase-producing Acinetobacter baumannii, Algeria [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2010
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, ISSN : 0934-9723, DOI : 10.1007/s10096-010-1011-2, Issue : 11, Volume : 29, pp. 1457-1458, November 2010.
DRISSI, M., POIREL, L., MUGNIER, P. D., BABA AHMED, Z., NORDMANN, P.   +4 more
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In vitro activity of cefiderocol against carbapenemase-producing and meropenem-non-susceptible Gram-negative bacteria collected in the Japan Antimicrobial Resistant Bacterial Surveillance

Journal of Global Antimicrobial Resistance
Objectives: The treatment options available for infections caused by multidrug-resistant Gram-negative pathogens are often limited. Cefiderocol (CFDC) is a novel siderophore cephalosporin that exhibits activity against these pathogens.
Shizuo Kayama, Sayoko Kawakami, Kohei Kondo, Norikazu Kitamura, Liansheng Yu, Wataru Hayashi, Koji Yahara, Yo Sugawara, Motoyuki Sugai   +8 more
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Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

Biotechnology and Bioengineering, EarlyView.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu, Rachael M. Harrower, Ziang Li, Angela C. Brown   +3 more
wiley   +1 more source

Carbapenemase-Producing Organisms: A Global Scourge [PDF]

Clinical Infectious Diseases, 2017
The dramatic increase in the prevalence and clinical impact of infections caused by bacteria producing carbapenemases is a global health concern. Carbapenemase production is especially problematic when encountered in members of the family Enterobacteriaceae.
Julie A. Segre, John Conly, Laurent Poirel, Brandi Limbago, Lars F. Westblade, Eileen M. Burd, Robert A. Bonomo, Robert A. Bonomo   +7 more
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Efficacy of Essential Oil of Algrizea minor Sobral, Faria & Proença (Myrtaceae) in Combating Methicillin‐resistant Staphylococcus aureus: Antibacterial and Virulence Modulation Studies Conducted In Vitro and In Vivo

Chemistry &Biodiversity, EarlyView.
This study explored the antibacterial, antivirulence, and in vivo effects of Algrizea minor essential oil (EOAM), against MRSA isolates. Chemical analysis by GC‐MS has been performed. The oil exhibited synergistic effects when combined with amoxicillin and oxacillin, inhibiting biofilm formation and reducing S. aureus‐induced hemolysis.
Amanda Vieira de Barros, Bruno Oliveira de Veras, Henrique Nelson Pereira Costa Júnior, Raudiney Frankilin Vasconcelos Mendes, Patryck Érmerson Monteiro dos Santos, Jael Fernandes Tavares, Daniela Maria do Amaral Ferraz Navarro, Rafael Matos Ximenes, Patrícia Maria Guedes Paiva, Clovis Macedo Bezerra Filho, Josinaldo Alves da Silva, Márcia Vanusa da Silva, João Paulo Martins de Lima, Henrique Douglas Melo Coutinho, Maria Betânia Melo de Oliveira   +14 more
wiley   +1 more source