Results 41 to 50 of about 29,439 (214)

Carbapenemase-producingEnterobacteriaceae, U.S. Rivers

Emerging Infectious Diseases, 2005
Our study was initiated by previous isolation of 30 imipenem-resistant, gram-negative rods from 7 of 16 U.S. rivers sampled from 1999 to 2001. Imipenem hydrolysis was detected in 22 of those isolates identified as Enterobacter asburiae. Random amplified polymorphism DNA analysis showed that these E. asburiae isolates were genetically indistinguishable.
Cécile Aubron, Laurent Poirel, Ronald J Ash, Patrice Nordmann   +3 more
openaire   +3 more sources

Molecular Respiratory Pathogen Panels in Lung Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Molecular respiratory pathogen panels are an innovative tool for the rapid detection of respiratory pathogens and antimicrobial resistance genes, offering the potential to improve diagnostic accuracy and guide timely antimicrobial therapy.
Andrea Lombardi
wiley   +1 more source

Prevalence and molecular determinants of carbapenemase-producing Klebsiella pneumoniae isolated from Jazan, Saudi Arabia

Journal of Infection in Developing Countries, 2023
Introduction: The World Health Organization (WHO) designated Carbapenem-resistant Enterobacterales (CRE), formerly Enterobacteriaceae, among the global priority list of antibiotic-resistant bacteria. The rate of CRE in Arabian countries, including Saudi
Thamer Brek, Ahmed K Alghamdi, Turki S Abujamel, Muhammad Yasir, Elaf M Alattas, Maryam S Hazazi, Ibrahim A Al-Zahrani   +6 more
doaj   +1 more source

Confronting Carbapenemase-Producing Klebsiella Pneumoniae

Future Microbiology, 2013
The ongoing spread of carbapenemase-producing (CP) multidrug-resistant enterobacteria, primarily Klebsiella pneumoniae, has undoubtedly caused a public health crisis of unprecedented dimensions. The scientific community has been struggling with these highly problematic nosocomial pathogens for more than a decade.
Markogiannakis, A., Tzouvelekis, L.S., Psichogiou, M., Petinaki, E., Daikos, G.L.   +4 more
openaire   +3 more sources

Colored Plastic Pollution Reshapes Aquatic Microbial Community and Resistance Profile via Divergent Pseudonatural Dissolved Organic Matter

Advanced Science, Volume 13, Issue 3, 14 January 2026.
By altering the quantity and chemical composition of polyethylene‐derived dissolved organic matter, plastic color dynamically regulates bacterial metabolic interactions, thereby reshaping community resistance expression and facilitating the dissemination of antibiotic resistance.
Shuting Fang, Shuqin Liu, Jingui Huang, Yiquan Huang, Chao Chen, Qijun Ruan, Pengran Guo, Gangfeng Ouyang   +7 more
wiley   +1 more source

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 235-244, January 2026.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu, Rachael M. Harrower, Ziang Li, Angela C. Brown   +3 more
wiley   +1 more source

Novel nanoparticle‐mediated plasmid delivery in bacteria for difficult applications

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 1, Page 123-134, January 2026.
Abstract BACKGROUND This study presents the development and application of magnetite/silver‐pDMAEMA‐PEG‐BUFII nanobioconjugates as an advanced plasmid delivery system in bacteria. These nanobioconjugates demonstrated superior efficiency compared to traditional methods in four challenging applications: (i) genomic editing in Gram‐positive bacteria; (ii)
Laura D. Páez‐Angarita, Laura X. Henao, Sebastián Jaramillo‐Toro, Valentina Quezada, Silvia Restrepo, Juan C. Cruz, Johana Husserl   +6 more
wiley   +1 more source

Evaluation of a modified meropenem hydrolysis assay on a large cohort of KPC and VIM carbapenemase-producing Enterobacteriaceae. [PDF]

PLoS ONE, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have spread globally and represent a serious and growing threat to public health. The introduction of rapid and sensitive methods for the detection of carbapenemase-producing bacteria is of increasing ...
Adriana Calderaro, Mirko Buttrini, Maddalena Piergianni, Sara Montecchini, Monica Martinelli, Silvia Covan, Giovanna Piccolo, Maria Cristina Medici, Maria Cristina Arcangeletti, Carlo Chezzi, Flora De Conto   +10 more
doaj   +1 more source

Carbapenemases: Partners in crime

Journal of Global Antimicrobial Resistance, 2013
Carbapenemases, β-lactamases that inactivate carbapenems and most β-lactam antibiotics, are most widely known for their ability to confer resistance to β-lactams. They include serine carbapenemases, such as the widespread KPC family of enzymes, and the metallo-β-lactamases that contain the IMP, NDM and VIM enzyme families acquired by Gram-negative ...
openaire   +2 more sources

Population Pharmacokinetic and Pharmacodynamic Prediction for Tebipenem Pivoxil Treatment of Pediatric Shigellosis

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Increasing antimicrobial resistance poses a serious challenge for the treatment of Shigella infections, and there is an urgent need for alternative antibacterial treatments. We conducted a clinical trial to investigate the efficacy of oral tebipenem pivoxil, compared to intravenous ceftriaxone, in Bangladeshi children with shigellosis.
Cindy X. Zhang, Sharika Nuzhat, Md Ridwan Islam, Syed Jayedul Bashar, Subhasish Das, Rukaeya Amin, Firdausi Qadri, Farhana Khanam, Dilruba Ahmed, Patricia B. Pavlinac, Mohammod Jobayer Chisti, Tahmeed Ahmed, Samuel L. M. Arnold   +12 more
wiley   +1 more source