Results 51 to 60 of about 28,072 (215)

Antimicrobial Susceptibility Profile of Escherichia coli Isolates From Artisanal Colonial Cheese in Southern Brazil

open access: yesFood Safety and Health, EarlyView.
This study evaluated the antimicrobial susceptibility profile of Escherichia coli isolated from artisanal colonial cheese from Brazil. Sixty percent of the isolates showed resistance to at least one antimicrobial, no ESBL was found, genes blaTEM and tetB were found simultaneously in four isolates.
Luísa Aimée Schmitt Lobe   +14 more
wiley   +1 more source

Carbapenemases: Partners in crime

open access: yesJournal of Global Antimicrobial Resistance, 2013
Carbapenemases, β-lactamases that inactivate carbapenems and most β-lactam antibiotics, are most widely known for their ability to confer resistance to β-lactams. They include serine carbapenemases, such as the widespread KPC family of enzymes, and the metallo-β-lactamases that contain the IMP, NDM and VIM enzyme families acquired by Gram-negative ...
openaire   +3 more sources

Evaluation of a modified meropenem hydrolysis assay on a large cohort of KPC and VIM carbapenemase-producing Enterobacteriaceae. [PDF]

open access: yesPLoS ONE, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have spread globally and represent a serious and growing threat to public health. The introduction of rapid and sensitive methods for the detection of carbapenemase-producing bacteria is of increasing ...
Adriana Calderaro   +10 more
doaj   +1 more source

Prevalence and molecular determinants of carbapenemase-producing Klebsiella pneumoniae isolated from Jazan, Saudi Arabia

open access: yesJournal of Infection in Developing Countries, 2023
Introduction: The World Health Organization (WHO) designated Carbapenem-resistant Enterobacterales (CRE), formerly Enterobacteriaceae, among the global priority list of antibiotic-resistant bacteria. The rate of CRE in Arabian countries, including Saudi
Thamer Brek   +6 more
doaj   +1 more source

Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent Klebsiella pneumoniae

open access: yesiMeta, EarlyView.
The global emergence of hypervirulent, carbapenem‐resistant Klebsiella pneumoniae (hvCRKP) poses a paradox: why do such dangerous clones remain geographically confined? By analyzing over 2500 CC23 genomes across 90 years, we uncover a core evolutionary constraint—virulence and resistance rarely coexist without trade‐offs. Potent carbapenemases (blaKPC,
Yuchen Wu   +15 more
wiley   +1 more source

Carbapenemases in Enterobacteriaceae: Detection and Antimicrobial Therapy [PDF]

open access: yesFrontiers in Microbiology, 2019
Carbapenem-resistant Enterobacteriaceae (CRE) have spread rapidly around the world in the past few years, posing great challenges to human health. The plasmid-mediated horizontal transmission of carbapenem-resistance genes is the main cause of the surge in the prevalence of CRE.
Hong Du, Haifang Zhang, Xiaoyan Cui
openaire   +4 more sources

Phenotypic, Targeted Genotypic, and Antimicrobial Susceptibility Profiling of Extended‐Spectrum β‐Lactamase Production and Exclusive blaOXA−48 Gene Detection in Escherichia coli and Klebsiella pneumoniae Isolates From a South Lebanese Hospital

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study investigates the prevalence of multidrug‐resistant Escherichia coli and Klebsiella pneumoniae in South Lebanon's Saida region, focusing on ESBL and carbapenemase production. Results showed a high prevalence of ESBL producers (89.5%) and a lower rate of carbapenemase producers (10.5%), with blaCTX‐M being the most common ESBL gene.
Aya Kahil, Elie Salem Sokhn
wiley   +1 more source

Prevalence of Carbapenemases in Acinetobacter baumannii [PDF]

open access: yes, 2012
Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen and causes a variety of nosocominal infections especially in Intensive Care Units (ICU’s) (BergogneBerezin & Towner, 1996; Villegas & Harstein, 2003). These infections include bacteraemia, surgical-site infections, secondary meningitis, urinary tract infections and ventilator
M.M. Ehlers, J.M. Hughes, M.M. Kock
openaire   +3 more sources

Novel nanoparticle‐mediated plasmid delivery in bacteria for difficult applications

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This study presents the development and application of magnetite/silver‐pDMAEMA‐PEG‐BUFII nanobioconjugates as an advanced plasmid delivery system in bacteria. These nanobioconjugates demonstrated superior efficiency compared to traditional methods in four challenging applications: (i) genomic editing in Gram‐positive bacteria; (ii)
Laura D. Páez‐Angarita   +6 more
wiley   +1 more source

Structural and Functional Aspects of Class A Carbapenemases [PDF]

open access: yesCurrent Drug Targets, 2016
The fight against infectious diseases is probably one of the greatest public health challenges faced by our society, especially with the emergence of carbapenem-resistant gram-negatives that are in some cases pan-drug resistant. Currently,β-lactamase-mediated resistance does not spare even the newest and most powerful β-lactams (carbapenems), whose ...
Naas, Thierry   +2 more
openaire   +6 more sources

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