Results 101 to 110 of about 24,596 (232)

Structure, Genetics and Worldwide Spread of New Delhi Metallo-β-lactamase (NDM): a threat to public health [PDF]

, 2017
Background: The emergence of carbapenemase producing bacteria, especially New Delhi metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health concern.
Khan, Asad U, Maryam, Lubna, Zarrilli, Raffaele   +2 more
core   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

High Prevalence of Multidrug-Resistant Bacterial Colonization Among Patients and Healthcare Workers in a Rural Ethiopian Hospital

Antibiotics
Background/Objectives: Multidrug-resistant (MDR) bacterial colonization poses a significant risk for subsequent infections, especially within hospital environments.
Elena Hidalgo, Teresa Alvaredo-Carrillo, Josefina-Marina Gil-Belda, Clara Portela-Pino, Clara Bares-Moreno, Sara Jareño-Moreno, Paula de la Fuente, Lucía Platero, Ramón Pérez-Tanoira   +8 more
doaj   +1 more source

QM/MM simulations as an assay for carbapenemase activity in class A β-lactamases [PDF]

, 2014
Carbapenemases are distinguished from carbapenem-inhibited β-lactamases with a protocol involving QM/MM free energy simulations of acyl–enzyme deacylation, requiring only the enzyme 3D structure as input.
Chudyk, Ewa I, Jones, Charlotte, Limb, Michael A L, Mulholland, Adrian J, Spencer, James, van der Kamp, Marc W   +5 more
core   +2 more sources

Antimicrobial‐Resistance Genetic Markers Among Multidrug‐Resistant Enterobacteriaceae and Acinetobacter spp. From Vegetable Market Chains in Ethiopia

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Schematic overview of the study workflow explaining isolation of lactose‐fermenting Gram‐negative bacteria from farms and supermarkets, antimicrobial susceptibility testing, detection of resistance genes by PCR, and ERIC‐PCR to evaluate genetic diversity and relatedness among isolates.
Hemen Tesfaye, Adey Feleke Desta, Ahu Reis, Mine Egin, Osman Birol Ozgumus, Neslihan Akarsu, Mujib Abdulkadir, Haile Alemayehu, Tadesse Eguale, Ali Osman Kilic   +9 more
wiley   +1 more source

Identification and phylogenetic analysis of carbapenemase genes from clinical strains of Klebsiella pneumoniae

Journal of Infection in Developing Countries
Introduction: Klebsiella pneumoniae is an encapsulated Gram-negative bacterium that is responsible for numerous infections in healthcare facilities worldwide and is frequently isolated. The World Health Organization has listed K.
Boukaré Kaboré, Ganamé A Ouédraogo, Henri S Ouédraogo, Hama Cissé, Oumarou Zongo, Koudbi J Zongo, Boukaré Zeba, Idrissa Sanou, Aly Savadogo   +8 more
doaj   +1 more source

Klebsiella pneumoniae ST307 with blaOXA-181, South Africa, 2014–2016

Emerging Infectious Diseases, 2019
Klebsiella pneumoniae sequence type (ST) 307 is an emerging global antimicrobial drug–resistant clone. We used whole-genome sequencing and PCR to characterize K.
Michelle Lowe, Marleen M. Kock, Jennifer Coetzee, Ebrahim Hoosien, Gisele Peirano, Kathy-Ann Strydom, Marthie M. Ehlers, Nontombi M. Mbelle, Elena Shashkina, David B. Haslam, Puneet Dhawan, Robert J. Donnelly, Liang Chen, Barry N. Kreiswirth, Johann D.D. Pitout   +14 more
doaj   +1 more source

Carbapenemase-producingAcinetobacterspp. in Cattle, France

Emerging Infectious Diseases, 2012
To the Editor: Multidrug resistance in bacteria isolated from animals is an emerging phenomenon, mirroring what is happening among humans. During the past decade, expanded-spectrum β-lactamases in Enterobacteriaceae from humans (1) and animals (2) worldwide have been reported.
Poirel, Laurent, Berçot, Béatrice, Millemann, Yves, Bonnin, Rémy A., Pannaux, Glenn, Nordmann, Patrice   +5 more
openaire   +3 more sources

Methodological Evaluation of Carbapenemase Detection by Different Methods

Polish Journal of Microbiology
The global proliferation of carbapenemase-producing bacteria (CPB) has garnered significant attention worldwide. Early diagnosis of CPB and accurate identification of carbapenemases are crucial for preventing the spread of CPB and ensuring targeted ...
Gao Nana, Zhou Jing, Li Ge, Liu Runde, Lu Guoping, Shen Jilu   +5 more
doaj   +1 more source

A pilot study of the clinical significance and outcomes of infections in the ICU caused by colistin-resistant Klebsiella pneumoniae

Вестник анестезиологии и реаниматологии
The objective was to study the risk factors, outcomes of infections caused by colistin-resistant K. pneumonia (CRKP) and to evaluate the  sensitivity of these microorganisms to antibacterial agents to determine the most adequate antibiotic therapy ...
I. N. Sychev, O. V. Ignatenko, S. V. Yakovlev, L. V. Fedina, E. N. Burmistrova, M. P. Suvorova, T. D. Rastvorova, E. V. Strigunkova, R. Kh. Mukhamadiev   +8 more
doaj   +1 more source