Results 91 to 100 of about 24,917 (198)

Resistance and virulence features of hypermucoviscous Klebsiella pneumoniae from bloodstream infections: Results of a nationwide Italian surveillance study

Frontiers in Microbiology, 2022
Among Enterobacterales, Klebsiella pneumoniae (Kp) is one of the major opportunistic pathogens causing hospital-acquired infections. The most problematic phenomenon linked to Kp is related to the dissemination of multi-drug resistant (MDR) clones ...
Fabio Arena, Fabio Arena, Fabio Arena, Giulia Menchinelli, Vincenzo Di Pilato, Riccardo Torelli, Alberto Antonelli, Alberto Antonelli, Lucia Henrici De Angelis, Marco Coppi, Marco Coppi, Maurizio Sanguinetti, Maurizio Sanguinetti, Gian Maria Rossolini, Gian Maria Rossolini, Gian Maria Rossolini   +15 more
doaj   +1 more source

Metagenomic and culture‐based insights into host and plasmid contexts of high‐risk ARGs in poultry farm environments

iMetaOmics, EarlyView.
Shotgun metagenomics and culture‐based isolate genomics revealed position‐associated high‐risk antibiotic resistance genes (ARGs) signals across poultry manure piles and surrounding soils. Culture‐confirmed Enterobacteriaceae and IncHI2A‐related blaNDM‐5 plasmid backgrounds further highlight priority host‐ARG‐plasmid contexts for farm antimicrobial ...
Yaling Wang, Lianwei Ye, Linan He, Zhenlong Wu, Yiwen Yang, Sheng Chen   +5 more
wiley   +1 more source

Searching for carbapenemases in zoo animals [PDF]

, 2018
Searching for novel carbapenemases in zoo animals Degree project, Programme in Medicine Martin Thorslund 2018, Institute of Biomedicine, Gothenburg, Sweden 1.1 Introduction Carbapenems, a class of “last resort” antibiotics, are threatened by ...
Thorslund, Martin
core   +1 more source

An Xpert screen to identify carbapenemases

Indian Journal of Medical Microbiology, 2016
To prevent the spread of carbapenemases-producing Enterobacteriaceae (CPE) active surveillance, contact isolation and cohorting infected patients should be practiced. Rectal swabs for the Xpert MDRO-assay of 32 patients were included. 71.85% were positive for targets incorporated into the MDRO-assay; whereas 28% were phenotypically not CRE and Xpert ...
Mubin, Kazi, Chaitali, Nikam, Anjali, Shetty, Camilla, Rodrigues   +3 more
openaire   +2 more sources

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Carbapenemases: Partners in crime

Journal of Global Antimicrobial Resistance, 2013
Carbapenemases, β-lactamases that inactivate carbapenems and most β-lactam antibiotics, are most widely known for their ability to confer resistance to β-lactams. They include serine carbapenemases, such as the widespread KPC family of enzymes, and the metallo-β-lactamases that contain the IMP, NDM and VIM enzyme families acquired by Gram-negative ...
openaire   +2 more sources

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source

Antimicrobial Resistance: Carbapenemases-producing bacteria in livestock

, 2016
Carbapenems are antibiotics authorised for the treatment of humans and categorised by the World Health Organisation as critically important antimicrobials. Antibiotics of this kind should only be administered when there are strict indications, i.e.
German Federal Institute for Risk Assessment (BfR)
core   +1 more source

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii from Southern Brazil

Revista de Epidemiologia e Controle de Infecção, 2021
Carbapenem resistance in Acinetobacter baumannii has reached extremely high levels worldwide and class D OXA-type carbapenemases are the main associated mechanism.
Gabriel de Paula Gollino, Bruna Machado Escobar, Ilson Dias da Silveira, Rosa Helena Robales Siqueira, Joseane Cristina Ferreira, Ana Lúcia da Costa Darini, Vanessa Bley Ribeiro   +6 more
doaj   +1 more source

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

Veterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan, Nicola Williams, Jenny Llewelyn, Sam Haldenby, Gina Pinchbeck, Dorina Timofte   +5 more
wiley   +1 more source