Prevalence of class D carbapenemases among extended-spectrum β-lactamases producing Escherichia coli isolates from educational hospitals in Shahrekord [PDF]
Introduction: Extended-spectrum β-lactamases (ESBLs) are a set of plasmid-borne, various and quickly evolving enzymes that are a main therapeutic issue now-a-days for inpatient and outpatient treatment.
Damavandi, M.-S. +2 more
core +1 more source
Relevance. In the last decade, there has been an increase in the isolation of antibiotic-resistant microorganisms in community settings. Colonization and asymptomatic carriage of extended-spectrum beta-lactamase and carbapenemase producers can be a ...
O. G. Ni +7 more
doaj +1 more source
In vitro activity of cefepime/zidebactam (WCK 5222) against Gram-negative bacteria [PDF]
Background: Diazabicyclooctanes (DBOs) inhibit class A, class C and some class D β-lactamases. A few also bind PBP2, conferring direct antibacterial activity and a β-lactamase-independent ‘enhancer' effect, potentiating β-lactams targeting PBP3.
Livermore, David M +4 more
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Background. Despite the advances achieved in transplantation, the problem of septic infection in this field still remains crucial. This can largely be attributed to the immunocompromised status of patients, and the constant growth in the number of ...
T. V. Chernenkaya +3 more
doaj +1 more source
Susceptibility to 16 antimicrobial agents in 421 Klebsiella pneumoniae strains, isolated in a multidisciplinary medical centre from patients with nosocomial infections in 2015, was tested.
N. S. Kozlova +2 more
doaj +1 more source
Detection of SPM-1-Producing Pseudomonas aeruginosa and Class D beta-Lactamase-Producing Acinetobacter baumannii Isolates by Use of Liquid Chromatography-Mass Spectrometry and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry [PDF]
This study evaluates the accuracy of liquid chromatography-mass spectrometry (LC-MS) and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) for detecting carbapenem hydrolytic activity among SPM-1-, GIM-1-, and GES-5-
Assis, Diego M. +6 more
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Bacteremia caused by an Acinetobacter junii strain harboring class 1 integron and diverse DNA mobile elements [PDF]
INTRODUCTION: Infections caused by Acinetobacter junii are rarely reported. However, some outbreaks of septicemia in neonates and pediatric oncology patients, as well as meningitis, peritonitis, and ocular infection have been described.
Almuzara, Marisa +7 more
core +1 more source
Carbapenemase-producingKlebsiella pneumoniaeand Hematologic Malignancies
To the Editor: Until a few years ago, the most frequent microbiologically documented cause of severe bloodstream infections among patients with hematologic malignancies was gram-positive bacteria (1). However, over the years, gram-negative bacteria have become the main infectious cause of death among patients with hematologic malignancies, and rates of
Pagano, Livio +7 more
openaire +4 more sources
The emergence and spread of carbapenem-resistant Gram-negative bacteria is a worldwide emerging public health threat responsible for large number of nosocomail infections.
Saad L. Hamed, Noor A. Hasoon
doaj +1 more source
Rapid detection of carbapenemase-producing Enterobacteriaceae. [PDF]
To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem.
Dortet, L, Nordmann, P, Poirel, L
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