Results 71 to 80 of about 20,063 (216)

What do We Know so Far about Ges Carbapenemases, and What Threat do They Pose?

Postępy Mikrobiologii
Carbapenemases, classified as bacterial enzymes, have the ability to hydrolyze carbapenems – important broad-spectrum antibiotics. This work attempts to summarize the information on the diversity of Guiana Extended-Spectrum (GES) subgroup of ...
Rutkowski Kamil, Osnytskyy Anton, Ślifierska Magdalena, Jarząbek Paulina, Bielec Filip, Pastuszak-Lewandoska Dorota, Brauncajs Małgorzata   +6 more
doaj   +1 more source

Intra- and Extra-Hospital Dissemination of IMP-22-Producing Klebsiella pneumoniae in Northern Portugal: The Breach of the Hospital Frontier Toward the Community

Frontiers in Microbiology, 2021
The emergence of infections (and colonization) with Enterobacteriaceae-producing carbapenemases is a threatening public health problem. In the last decades, we watched an isolated case becoming a brutal outbreak, a sporadic description becoming an ...
Daniela Gonçalves, Daniela Gonçalves, Daniela Gonçalves, Daniela Gonçalves, Pedro Cecílio, Alberta Faustino, Carmen Iglesias, Fernando Branca, Alexandra Estrada, Helena Ferreira, Helena Ferreira   +10 more
doaj   +1 more source

Type IV‐Dominated Plasmid‐Encoded CRISPR‐Cas Systems Are Enriched in Multireplicon and Multi‐Stressor Resistance Plasmids Across the Global Plasmidome

Molecular Microbiology, EarlyView.
Screening 72,555 plasmid sequences reveals that intact CRISPR‐Cas systems are rare (1.03%) but strongly enriched in multireplicon and multi‐stressor resistance plasmids, with Type IV‐A as the dominant subtype. These findings implicate plasmid‐encoded CRISPR‐Cas as non‐randomly retained elements of structurally complex and high‐risk backbones.
Hannay Crystynah Almeida de Souza, Anamaria Mota Pereira dos Santos, Arlen Carvalho de Oliveira Almeida, Carlos Adam Conte Junior, Pedro Panzenhagen   +4 more
wiley   +1 more source

Epidemiology and Genetic Traits of Carbapenemase-Producing Enterobacterales: A Global Threat to Human Health

Antibiotics
Carbapenemase-producing Enterobacterales (CPE) represent an important threat to global health, resulting in an urgent issue in clinical settings. CPE often exhibit a multidrug-resistant (MDR) phenotype, thus reducing the antimicrobial armamentarium, with
Gualtiero Alvisi, Antonio Curtoni, Rossella Fonnesu, Aurora Piazza, Caterina Signoretto, Giorgia Piccinini, Davide Sassera, Paolo Gaibani   +7 more
doaj   +1 more source

Prevalence of Carbapenemases in Carbapenem-Resistant Acinetobacter baumannii Isolates from the Kingdom of Bahrain

Antibiotics, 2023
Background: Acinetobacter baumannii is regarded as a significant cause of death in hospitals. The WHO recently added carbapenem-resistant Acinetobacter baumannii (CRAB) to its global pathogen priority list.
Nouf Al-Rashed, Khalid M. Bindayna, Mohammad Shahid, Nermin Kamal Saeed, Abdullah Darwish, Ronni Mol Joji, Ali Al-Mahmeed   +6 more
doaj   +1 more source

Bacterial Agents and Their Multidrug‐Resistance Profile Among Patients Suspected of Bacterial Infections in Hakim Gizaw Hospital, Debre Berhan, Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Antimicrobial resistance is a global threat. Bacteria showed higher resistance in Ethiopia, and up‐to‐date data on it is urgently required for effective interventions. This study aimed to determine occurrence of multi‐drug‐resistant (MDR) bacterial isolates among patients presented to Hakim Gizaw Hospital (HGH).
Tizazu Zenebe Zelelie, Ermias Endewunetu, Yosef Temesgen, Demissew Shenkute Gebreyes, Zenawork Sahile, Biniam Mekonnen, Getachew Bizuneh, Asrat Berihun, Berhanu Yitayew   +8 more
wiley   +1 more source

Detectable carbapenemases for each assay according to the respective user manual.

, 2018
Detectable carbapenemases for each assay according to the respective user manual.
Niels Pfennigwerth (5244080), Stephan Rösner (5244083), Dietrich Mack (273758), Uta Küsters (5244077), Kevin Gehlweiler (5244086), Kirsten Hübner (4002017), Mathias Kolbert (5244074)   +6 more
core   +1 more source

Guideline for phenotypic screening and confirmation of carbapenemases in Enterobacteriaceae.

, 2010
Adequate detection of carbapenemase-producing Enterobacteriaceae is crucial for infection control measures and appropriate choice of antimicrobial therapy.
Voss, A., Leverstein-van Hall, M.A., Cohen Stuart, J., et al., Stuart, James Cohen, Hall, Maurine A. Leverstein-Van, Maurine A. Leverstein-Van Hall, James Cohen Stuart   +7 more
core   +2 more sources

Global emergence of double and multi-carbapenemase producing organisms: epidemiology, clinical significance, and evolutionary benefits on antimicrobial resistance and virulence

Microbiology Spectrum
Redundant carbapenemase-producing (RCP) bacteria, which carry double or multiple carbapenemases, represent a new and concerning phenomenon. The objective of this study is to conduct a comprehensive analysis of the epidemiology and genetic mechanisms of ...
Pei-Bo Yuan, Li-Ting Dai, Qi-Ke Zhang, Yu-Xia Zhong, Wan-Ting Liu, Ling Yang, Ding-Qiang Chen   +6 more
doaj   +1 more source

Cefiderocol against Multi-Drug and Extensively Drug-Resistant Escherichia coli: An In Vitro Study in Poland

Pathogens, 2022
Cefiderocol (CFDC) is a novel, broad-spectrum siderophore cephalosporin with potential activity against multi-drug (MDR) and extensively drug-resistant (XDR) Enterobacterales, including carbapenem-resistant strains.
Patrycja Zalas-Więcek, Katarzyna Płachta, Eugenia Gospodarek-Komkowska   +2 more
doaj   +1 more source