Results 71 to 80 of about 24,596 (232)
Microbiology SpectrumRedundant carbapenemase-producing (RCP) bacteria, which carry double or multiple carbapenemases, represent a new and concerning phenomenon. The objective of this study is to conduct a comprehensive analysis of the epidemiology and genetic mechanisms of ...
Pei-Bo Yuan +6 more
doaj +1 more source
Transplant Infectious Disease, EarlyView.This study reveals that infections are highly prevalent in pediatric IEI patients after umbilical cord blood transplantation, with early‐stage infections and bloodstream infections strongly associated with poorer survival. These findings advocate for risk‐stratified surveillance and preemptive strategies in high‐risk subgroups.
Zhongling Wei +8 more
wiley +1 more source
AntibioticsCarbapenemase-producing Enterobacterales (CPE) represent an important threat to global health, resulting in an urgent issue in clinical settings. CPE often exhibit a multidrug-resistant (MDR) phenotype, thus reducing the antimicrobial armamentarium, with
Gualtiero Alvisi +7 more
doaj +1 more source
Frontiers in Microbiology, 2021 The emergence of infections (and colonization) with Enterobacteriaceae-producing carbapenemases is a threatening public health problem. In the last decades, we watched an isolated case becoming a brutal outbreak, a sporadic description becoming an ...
Daniela Gonçalves +10 more
doaj +1 more source
Clonal diversity of Acinetobacter baumannii from diabetic patients in Saudi Arabian hospitals [PDF]
, 2014 Carbapenem-resistant Acinetobacter baumannii (CR-AB) represents a major health-care problem causing high rates of morbidity and mortality. This study investigated the clonality of CR-AB isolated from diabetic patients from different regions in Saudi ...
Abdalhamid +11 more
core +2 more sources
Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano +22 more
wiley +1 more source
Carbapenemase-producing Enterobacteriaceae in transplant patients
Journal of Antimicrobial Chemotherapy, 2021 Abstract Carbapenemase-producing Enterobacteriaceae (CPE) are a serious public health concern and represent a major threat to immunocompromised hosts, including solid organ (SOT) and stem cell transplant (HSCT) recipients. Transplant patients are at particular risk of developing CPE colonization and/or infection due to their frequent ...
Giannella M. +3 more
openaire +3 more sources
Microbiology SpectrumRapid and reliable detection of carbapenemase-producing Enterobacterales (CPE) is crucial for prompt treatment and infection control. Most assays target the primary four enzymes (KPC, OXA-48-like, VIM, and NDM), often missing less common variants (e.g ...
Lukas Schaffarczyk +5 more
doaj +1 more source
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Phage therapy shows promising efficacy against MDR, XDR, and PDR Pseudomonas aeruginosa infections across different models and administration routes. Evidence highlights reduced mortality, bacterial clearance, and synergy with antibiotics, while emphasizing the need for standardized protocols and advanced delivery systems to support clinical ...
Gustavo Aparecido da Cunha +7 more
wiley +1 more source
PLoS ONEKlebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. Carbapenemases are enzymes that help bacteria to exhibit the strongest resistance against antibiotics ...
Agata Pruss +9 more
doaj +1 more source