Results 71 to 80 of about 17,864 (222)

Application of mass spectrometry in phenotypic detection of carbapenemases. [PDF]

, 2017
The aim of this thesis was to determine activity of carbapenemases in Pseudomonas spp. isolates using mass spectrometry. There was created a new MALDI-TOF software based on Bruker‘s recommendations, which was able to detect activity of carbapenemases ...
Gorbikova, Evelina,
core  

Epidemiology and Genetic Traits of Carbapenemase-Producing Enterobacterales: A Global Threat to Human Health

Antibiotics
Carbapenemase-producing Enterobacterales (CPE) represent an important threat to global health, resulting in an urgent issue in clinical settings. CPE often exhibit a multidrug-resistant (MDR) phenotype, thus reducing the antimicrobial armamentarium, with
Gualtiero Alvisi, Antonio Curtoni, Rossella Fonnesu, Aurora Piazza, Caterina Signoretto, Giorgia Piccinini, Davide Sassera, Paolo Gaibani   +7 more
doaj   +1 more source

Cefiderocol against Multi-Drug and Extensively Drug-Resistant Escherichia coli: An In Vitro Study in Poland

Pathogens, 2022
Cefiderocol (CFDC) is a novel, broad-spectrum siderophore cephalosporin with potential activity against multi-drug (MDR) and extensively drug-resistant (XDR) Enterobacterales, including carbapenem-resistant strains.
Patrycja Zalas-Więcek, Katarzyna Płachta, Eugenia Gospodarek-Komkowska   +2 more
doaj   +1 more source

Genetic support of carbapenemases in double carbapenemase producer Klebsiella pneumoniae isolated in the Arabian Peninsula [PDF]

Acta Microbiologica et Immunologica Hungarica, 2018
Enterobacteriaceae co-producing NDM- and OXA-48-type carbapenemases were encountered in higher frequency in the United Arab Emirates (UAE) than in the neighboring countries in our earlier study. The aim of this investigation was to characterize the seven double carbapenemase producer Klebsiella pneumoniae found in the region to assess ...
Al-Baloushi, Amna E., Pál, Tibor, Ghazawi, Akela, Sonnevend, Agnes   +3 more
openaire   +3 more sources

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

Combination of Oral Doxycycline and Rifampin for Pan‐Drug Resistant Klebsiella pneumoniae Infection: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari, Sepideh Elyasi, Farshad Abedi   +2 more
wiley   +1 more source

Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae.

PLoS ONE
Klebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. Carbapenemases are enzymes that help bacteria to exhibit the strongest resistance against antibiotics ...
Agata Pruss, Alicja Skierska, Paweł Kwiatkowski, Helena Masiuk, Joanna Jursa-Kulesza, Stefania Giedrys-Kalemba, Iwona Bilska, Monika Sienkiewicz, Maria V Melnyk, Barbara Dołęgowska   +9 more
doaj   +1 more source

Analysis of In Vitro Activity of Cefiderocol Against Carbapenem-Resistant Gram-Negative Bacilli by Broth Microdilution and Disk Diffusion Method: A Single-Center Study in Odisha, India

Infection and Drug Resistance, 2022
Gayatree Nayak, Bijayini Behera, Srujana Mohanty, Punyatoya Kar, Jayanti Jena Department of Microbiology, All India Institute of Medical Sciences [AIIMS], Bhubaneswar, Odisha, 751019, IndiaCorrespondence: Bijayini Behera, Department of Microbiology, All ...
Nayak G, Behera B, Mohanty S, Kar P, Jena J   +4 more
doaj  

Global Incidence of Carbapenemase-Producing Escherichia coli ST131

Emerging Infectious Diseases, 2014
We characterized Escherichia coli ST131 isolates among 116 carbapenemase-producing strains. Of isolates from 16 countries collected during 2008–2013, 35% belonged to ST131 and were associated with blaKPC, H30 lineage, and virotype C. This study documents
Gisele Peirano, Patricia Bradford, Krystyna M. Kazmierczak, Robert E. Badal, Meredith Hackel, Daryl J. Hoban, Johann D.D. Pitout   +6 more
doaj   +1 more source

Use of Ancillary Carbapenemase Tests To Improve Specificity of Phenotypic Definitions for Carbapenemase-Producing Enterobacteriaceae [PDF]

Journal of Clinical Microbiology, 2017
ABSTRACT Carbapenemase-producing Enterobacteriaceae (CPE) are a significant threat to public health. In 2015, CDC revised the surveillance definition for CPE to include all Enterobacteriaceae resistant to any carbapenem tested.
Shelley A, Miller, Janet A, Hindler, Angelo, Chengcuenca, Romney M, Humphries   +3 more
openaire   +2 more sources