Results 91 to 100 of about 39,994 (209)
AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)
United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén +44 more
wiley +1 more source
VIEW, Volume 7, Issue 3, June 2026.(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang +9 more
wiley +1 more source
Cefdinir binding to a class A β‐lactamase revealed by serial cryo‐crystallography
Acta Crystallographica Section D, Volume 82, Issue 6, Page 672-682, June 2026.Serial cryo‐crystallography reveals the structure of the extended‐spectrum β‐lactamase CTX‐M‐14 in complex with the third‐generation cephalosporin antibiotic cefdinir.One of the most common resistance mechanisms against antibiotics employed by Gram‐negative bacteria involves the production of β‐lactamases, resulting in rapid hydrolysis of the ...
Gargi Gore +4 more
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 6, June 2026.This study isolated and identified a novel lytic phage that infects Pseudomonas aeruginosa. Henu5 exhibited good physicochemical stability. Additionally, the phage‐resistant mutants showed fitness trade‐offs in growth, virulence and antibiotic susceptibility, along with in vivo fitness, which might direct future phage selection in clinical settings ...
Salwa E. Gomaa +7 more
wiley +1 more source
Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.Nigerian agricultural soils harbour diverse Streptomyces species producing novel antimicrobial secondary metabolites. Genomic mining revealed 187 biosynthetic gene clusters, leading to isolation of twelve new compounds with potent activity against multidrug‐resistant pathogens, including MRSA and vancomycin‐resistant Enterococcus. ABSTRACT Streptomyces
David Adeiza Zakari +4 more
wiley +1 more source
European Respiratory Review, 2007 Inappropriate initial antibiotic therapy in nosocomial pneumonia is associated with higher mortality, longer hospital stays and increased healthcare costs.
J. Rello
doaj
Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.Root extracts of Physalis alkekengi were examined for activity against multidrug‐resistant (MDR) Escherichia coli. The ethanolic extract suppressed bacterial growth, lowered biofilm formation by ~63%, and markedly reduced expression of luxS and fimH. Findings highlight P.
Mansoureh Esfandiyari Doolaby +2 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 11, Page 1487-1494, June 2026.This multicenter, observational study reveals distinct alterations in the microbial spectrum of spontaneous bacterial peritonitis (SBP) associated with proton pump inhibitor use. These results are especially relevant for guiding empiric antibiotic therapy of SBP.
Philip Kitchen +13 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 6, June 2026.ABSTRACT Nacubactam is a β‐lactamase inhibitor. Early‐phase studies with 1000/2000/4000/8000 mg nacubactam monotherapy were not powered to assess proarrhythmic risk. Therefore, this analysis pooled electrocardiogram data from two placebo‐controlled studies to quantify potential effects of nacubactam on cardiac repolarization.
Jun Morita, Sue McKendrick, Yuji Kumagai
wiley +1 more source