Results 71 to 80 of about 53,901 (244)
Brazilian Journal of Infectious DiseasesIn vitro activity of doripenem and comparator antimicrobial agents was evaluated against Gram-negative bacilli recently isolated from Brazilian private hospitals that were enrolled in the INVITA-A-DORI Brazilian Study. A total of 805 unique Gram-negative
Ana Cristina Gales +4 more
doaj +1 more source
Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection
iMeta, EarlyView.This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu +5 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
A Catalytic Asymmetric Route to Carbapenems
, 2016 Efficient syntheses of N-acetyl thienamycin and epithienamycin A in their readily deprotected form are reported where three contiguous stereocenters are established in a single catalytic asymmetric azetidinone-forming reaction.
Craig A. Townsend (1319868) +2 more
core +1 more source
Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
Medicinal Research Reviews, EarlyView.ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Pharmacology Research & PerspectivesCarbapenems, known for their broad‐spectrum activity and used as last‐line treatment for severe drug‐resistant infections, are encountering increasing resistance.
Han Ngoc Bao Pham +9 more
doaj +1 more source
Antibody-Mediated Killing of Carbapenem-Resistant ST258
mBio, 2018 Carbapenem-resistant Klebsiella pneumoniae is a problem worldwide. A carbapenem-resistant K. pneumoniae lineage classified as multilocus sequence type 258 (ST258) is prominent in the health care setting in many regions of the world, including the United ...
Scott D. Kobayashi +6 more
doaj +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To assess microbial culture profiles and antibiotic resistance patterns in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) following fetal surgery compared with spontaneous PPROM without fetal surgery. Method This retrospective cross‐sectional study included women with multiple pregnancies and PPROMs < 34 ...
Ohad Houri +9 more
wiley +1 more source
Prevalence of carbapenem resistance genes in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii from meat samples [PDF]
Medical Laboratory JournalBackground: Infections caused by bacteria transmitted from food, including carbapenem-resistant Enterobacteriaceae, Pseudomonas aeruginosa (P. aeruginosa), and Acinetobacter baumannii (A.
Maryam Rezaeian, Laleh Hoveida
doaj
mSystems, 2020 In this study, we examine the impact of transcriptional network rearrangements driven by horizontal gene acquisition in PhoP and SlyA regulons using as a case study a phytopathosystem comprised of potato tubers and the soft-rot pathogen Pectobacterium ...
Daniel Bellieny-Rabelo +3 more
doaj +1 more source