Results 71 to 80 of about 40,327 (214)

Klebsiella ESBL bacteremia-mortality and risk factors

Brazilian Journal of Infectious Diseases
Background: Extended spectrum β-lactamase (ESBL)-producing bacteria have become recognized as a problem in South America. The aim of this study was to evaluate risk factors and mortality rate in bacteremia caused by ESBL-producing Klebsiella pneumoniae ...
Felipe Francisco Tuon, Margot Kruger, Marcos Terreri, Sergio R Penteado-Filho, Lucas Gortz   +4 more
doaj   +1 more source

The Synergy Between a Silver‐Ruthenium Antimicrobial and Aminoglycosides Is Based on Severe Macromolecular Damage

Molecular Microbiology, EarlyView.
AGXX enhances aminoglycoside activity against multidrug‐resistant pathogens such as uropathogenic Escherichia coli by increasing reactive oxygen species, causing protein aggregation and DNA damage. This effect is reduced by oxygen limitation or antioxidants. Polyphosphate protects cells from oxidative damage.
Emmanuel P. Oladokun, Gracious Y. Donkor, Julius K. Narh, Grady D. Jacobson, Cade Ward, Patrick O. Tawiah, Lisa K. Polzer, Kevin A. Edwards, Kyle A. Floyd, Jan‐Ulrik Dahl   +9 more
wiley   +1 more source

Results of the national surveillance of antimicrobial resistance of Enterobacteriaceae and Gram negative bacilli in health care-associated infections in Colombia, 2012-2014

Biomédica: revista del Instituto Nacional de Salud, 2017
Introduction: The Colombian National Antimicrobial Resistance Monitoring System for the surveillance of healthcare-associated infections was set up to meet this problem in the third quarter of 2012.
María Victoria Ovalle, Sandra Yamile Saavedra, María Nilse González, Andrea Melissa Hidalgo, Carolina Duarte, Mauricio Beltrán   +5 more
doaj   +1 more source

Sparing carbapenem usage [PDF]

Journal of Antimicrobial Chemotherapy, 2017
Carbapenem resistance in Gram-negative bacteria is increasing in many countries and use of carbapenems and antibiotics to which resistance is linked should be reduced to slow its emergence. There are no directly equivalent antibiotics and the alternatives are less well supported by clinical trials.
openaire   +3 more sources

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Global Spread of Carbapenemase-producing Enterobacteriaceae

Emerging Infectious Diseases, 2011
Carbapenemases increasingly have been reported in Enterobacteriaceae in the past 10 years. Klebsiella pneumoniae carbapenemases have been reported in the United States and then worldwide, with a marked endemicity at least in the United States and Greece.
Patrice Nordmann, Thierry Naas, Laurent Poirel   +2 more
doaj   +1 more source

Impact of Advanced Age on Posttransplant Infections and Outcomes in Solid Organ Transplant Recipients: A Multicenter Cohort Study

Transplant Infectious Disease, EarlyView.
Advanced age (≥60 years) was independently associated with higher mortality in solid organ transplant recipients, despite similar infection incidence. Even a single infection episode significantly increased mortality risk, underscoring the need for close clinical monitoring in elderly patients.
Sibel Altunisik Toplu, Vildan Avkan Oguz, Esra Tanyel, Imran Hasanoglu, Bengu Tatar, Tuba Turunc, Gule Cinar, Yesim Uygun Kizmaz, Gulnur Kul, Adem Kose, Muammer Celik, Adam Uslu, Ebru Oruc, Ezgi Erdal Karakas, Nilay Danis, Yelda Deligoz Bildaci, Sezai Yilmaz, Yasar Bayindir, Hande Arslan   +18 more
wiley   +1 more source

Perioperative Prophylaxis in Pediatric Solid Organ Transplantation: A Baseline Stewardship Audit Using Routine Electronic Data

Transplant Infectious Disease, EarlyView.
Using routine electronic data from 164 pediatric transplants, we created reproducible stewardship measures of perioperative prophylaxis practice across transplant populations and protocol pathways. Starting prophylaxis was reliable, but continuation beyond intended stop targets—especially in abdominal transplantation—identified the clearest target for ...
Charles B. Foster, Kaitlyn Rivard, Venkatraman A. Arakoni, Blanca E. Gonzalez   +3 more
wiley   +1 more source

The oral penems and carbapenems

Clinical Microbiology Reviews
SUMMARY The penem and carbapenem antibiotics provide some of the broadest spectrum coverage available and generally should only be used when narrower options are unavailable. The majority of available carbapenems can only be administered parenterally, but two orally administered penems (faropenem and sulopenem) and one orally ...
Sena Sayood, Elizabeth Neuner, Rebekah Dumm, Sumanth Gandra   +3 more
openaire   +2 more sources

Early Onset Bacteremia in Kidney Transplant Recipients in the Current Era

Transplant Infectious Disease, EarlyView.
ABSTRACT Background Bloodstream infection (BSI) after kidney transplantation increases the risk of graft loss and mortality. We aimed to identify contemporary risk factors and outcomes of early BSI (eBSI) at our transplant center. Methods We conducted a retrospective chart review of adult kidney transplant recipients (KTRs) from 2019 to 2023.
Lana Hasan, Nabin K. Shrestha, Mathew Duck, Joshua Augustine, Richard Fatica, Alvin Wee, Christine E. Koval   +6 more
wiley   +1 more source