Results 81 to 90 of about 40,327 (214)

Predicting the Effect of Meropenem Against Klebsiella pneumoniae Using Minimum Inhibitory Concentrations Determined at High Inocula

Antibiotics
Background/Objectives: Assessing antibiotic MICs at high bacterial counts is likely to disclose hidden bacterial resistance and the inoculum effect if present and therefore also reveal potential decreased antibiotic effectiveness.
Maria V. Golikova, Kamilla N. Alieva, Elena N. Strukova, Julia R. Savelieva, Daria A. Kondratieva, Svetlana A. Dovzhenko, Mikhail B. Kobrin, Vladimir A. Ageevets, Alisa A. Avdeeva, Stephen H. Zinner   +9 more
doaj   +1 more source

Aetiology and Antibiotic Susceptibility of Common Bacterial Infections in Hospitalised Patients: A 2019 Multisite Cross‐Sectional Survey in Jakarta, Indonesia

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives To describe the aetiology and antibiotic susceptibility patterns of common bacterial infections in hospitalised patients in Jakarta, Indonesia. Methods We conducted a hospital‐wide point prevalence survey in six hospitals in 2019, capturing data from routinely ordered bacterial cultures taken before the start of antibiotic treatment.
Justin de Brabander, Erni J. Nelwan, Ralalicia Limato, Monik Alamanda, Manzilina Mudia, Enty Tjoa, Ifael Y. Mauleti, Maria Mayasari, Iman Firmansyah, T. Mannaria Jayati, Michèle van Vugt, H. Rogier van Doorn, Raph L. Hamers, Erni J. Nelwan, Ralalicia Limato, Manzilina Mudia, Monik Alamanda, Helio Guterres, Enty Enty, Y. Ifael, Maria Mayasari Mauleti, Iman Firmansyah, May Hizrani, Anis Karuniawati, Taralan Tambunan, Amin Soebandrio, Decy Subekti, Iqbal Elyazar, Mutia Rahardjani, Fitria Wulandari, Reinout van Crevel, H. Rogier van Doorn, Vu Thi Lan Huong, Nga Do Ti Thuy, Sonia Lewycka, Alex Broom, Raph L. Hamers   +36 more
wiley   +1 more source

Faecal Microbiota Transplantation Reduces Lesion Severity and Medication Use in Canine Atopic Dermatitis: A Randomised, Placebo‐Controlled, Double‐Blinded Clinical Trial

Veterinary Dermatology, EarlyView.
Background: Faecal microbiota transplantation (FMT) is an established therapy for gastrointestinal disease, yet its role in canine atopic dermatitis (cAD) remains unclear. Hypothesis/Objectives: We hypothesised that adjunctive FMT improves clinical severity and reduces symptomatic medication use in dogs with cAD.
Vera Felten, Erin Asley West, Franco Martini, Claude Favrot, Stefan Unterer, Jan Suchodolski, Michael Scharl, Harald Renz, Nina Maria Fischer, Ana Rostaher   +9 more
wiley   +1 more source

Green Synthesis of Iron Oxide Nanoparticles and Their Antibacterial Efficacy against Carbapenem-resistant Klebsiella pneumoniae in Bloodstream Infections

Biomedical and Biotechnology Research Journal
Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat to global public health by rendering traditional antibiotic treatments ineffective.
Rahul Harikumar Lathakumari, Leela Kakithakara Vajravelu, Jayaprakash Thulukanam, Vishnupriya Panneerselvam, Poornima Baskar Vimala, Dakshina Manoj Nair, Sujith Sri Surya Ravi   +6 more
doaj   +1 more source

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

Canine Multidrug-Resistant Pseudomonas aeruginosa Cases Linked to Human Artificial Tears–Related Outbreak

Emerging Infectious Diseases
We report 2 canine cases of carbapenemase-producing Pseudomonas aeruginosa within a United States veterinary hospital associated with a human outbreak linked to over-the-counter artificial tears.
Emma R. Price, Darby McDermott, Adrienne Sherman, Lakisha Kelley, Jason Mehr, Rebecca Greeley, Stephen D. Cole   +6 more
doaj   +1 more source

The Development and Validation of a Simple Method for the Determination of Meropenem Concentrations in Human Plasma Using High‐Performance Liquid Chromatography

Applied Research, Volume 5, Issue 4, August 2026.
A simple, rapid, and sustainable HPLC‐UV method was developed and validated to quantify meropenem in human plasma across a wide linear range (0.5–100 mg/L). Utilizing an efficient one‐step protein precipitation, this eco‐friendly approach is highly suited for routine clinical therapeutic drug monitoring and research purposes.
Asma Aboelezz, Maged Kharouba, Sherif Hanafy Mahmoud   +2 more
wiley   +1 more source

Toddlers and terriers: a One Health partnership to combat antimicrobial resistance

Journal of Small Animal Practice, EarlyView.
M. Prodanuk, F. Emdin
wiley   +1 more source

Successful Rapid Desensitization to Ceftazidime/Avibactam in a Patient With Cystic Fibrosis and Multidrug‐Resistant Pseudomonas aeruginosa Pneumonia: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Ceftazidime/avibactam (CAZ‐AVI) is an important therapeutic option for multidrug‐resistant (MDR) Pseudomonas aeruginosa infections; however, hypersensitivity reactions may preclude its use and create significant therapeutic challenges. We report a 21‐year‐old woman with cystic fibrosis and recurrent MDR P.
Zuoren Zhou, Jinqi Zhu, Ge Wu, Xi Kang, Qing Wang, Jie Liu, Yan Jiang   +6 more
wiley   +1 more source

Combination of Oral Doxycycline and Rifampin for Pan‐Drug Resistant Klebsiella pneumoniae Infection: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari, Sepideh Elyasi, Farshad Abedi   +2 more
wiley   +1 more source