Results 91 to 100 of about 37,965 (275)

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Production of functional human galectin-1 in transplastomic tobacco and simplified recovery via batch-mode purification

Frontiers in Plant Science
Plant molecular farming has established itself as a transformative technology for the cost-effective and sustainable production of biopharmaceuticals, offering scalable solutions to meet growing global demand.
Catalina Francisca Vater, Catalina Francisca Vater, Juan Manuel Pérez Sáez, Juan Carlos Stupirski, Mora Massaro, Federico Gabriel Mirkin, Fernando Félix Bravo-Almonacid, Fernando Félix Bravo-Almonacid, Gabriel Adrián Rabinovich, Gabriel Adrián Rabinovich, Gabriel Adrián Rabinovich, Mauro Miguel Morgenfeld, Mauro Miguel Morgenfeld   +12 more
doaj   +1 more source

A single N1-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes

Scientific Reports, 2018
The entire chemical modification repertoire of yeast ribosomal RNAs and the enzymes responsible for it have recently been identified. Nonetheless, in most cases the precise roles played by these chemical modifications in ribosome structure, function and ...
Sunny Sharma, Johannes David Hartmann, Peter Watzinger, Arvid Klepper, Christian Peifer, Peter Kötter, Denis L. J. Lafontaine, Karl-Dieter Entian   +7 more
doaj   +1 more source

The Role of Carbohydrate in Maintaining Extensin in an Extended Conformation [PDF]

, 1986
Joel P. Stafstrom, L. Andrew Staehelin
openalex   +1 more source

Geometrically‐Screened, Sterically‐Hindered Additive for Wide‐Temperature Aqueous Zinc‐Ion Batteries

Advanced Functional Materials, EarlyView.
A molecular‑engineering strategy combining steric hindrance tuning with geometric optimization identifies cellobiose as an ideal additive for aqueous zinc‑ion batteries, enabling stable Zn deposition across a wide temperature range from −30 to 50 °C. Abstract Aqueous zinc‐ion batteries (AZIBs) are emerging as a highly promising alternative to lithium ...
Sida Zhang, Shengyang Huang, Weigen Chen, Zuyang Hu, Dong Hyun Min, Jun Su Kim, Hao Fu, Young Soo Yun, Won‐Chul Cho, Byung‐Hyun Kim, Baoyu Li, Chengchao Li, Jingyu Sun, Ho Seok Park   +13 more
wiley   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

Advanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son, Kyusoon Pak, Taehoon Lee, Monica Celine Prayogo, Jinyoung Choi, Sukkyung Kang, Minjoo Kang, Byungkook Oh, Sang Yu Sun, Sanha Kim, Sung Gap Im, Sangyong Jon, Steve Park   +12 more
wiley   +1 more source

Transition From Lattice Oxygen to Radical‐Mediated Oxidation in Ammonium‐Intercalated Birnessite Catalysts for Selective Valorization of Biomass to Produce Formic Acid

Advanced Functional Materials, EarlyView.
The catalytic valorization of biomass represents an essential approach for achieving sustainable chemical production, with formic acid (FA) being recognized as a valuable platform chemical for hydrogen storage and environmentally friendly synthetic applications.
Yiqi Geng, Wei Xiong, Wenhua Xue, Jian Ye, Puranjan Mishra, Rajenahally V. Jagadeesh, Jun Zhao   +6 more
wiley   +1 more source

Design and Synthesis of E-Selectin Antagonists

CHIMIA, 2001
Selectin-mediated recruitment of leukocytes plays a crucial role in a number of diseases and pathological situations, for example in inflammation, reperfusion injury, rheumatoid arthritis and respiratory diseases.
Beat Ernst, Thomas Peters, Reinhold Oehrlein, Keith E. Norman, John L. Magnani, Wolfgang Jahnke, Beatrice Wagner, Christian Müller, Sébastien Marti, Zorica Dragic, Hartmuth C. Kolb   +10 more
doaj  

Placental protein 13

Journal of Circulating Biomarkers, 2018
Placental protein 13 (PP13), a glycan binding protein predominantly expressed in syncytiotrophoblast, dimeric in nature, lacks N-terminal signal peptide, bypasses the endoplasmic reticulum, and secretes into maternal circulation as exosomes or ...
Ranjeeta Gadde, Dayanand CD, SR Sheela
doaj   +1 more source

The Preferred Conformation of Oligosaccharides Derived from the Complex‐Type Carbohydrate Portions of Glycoproteins [PDF]

, 1982
Klaus Bock, Jan Arnarp, Jörgen Lōnngren   +2 more
openalex   +1 more source