Results 101 to 110 of about 876,956 (399)

Deletion of intragenic tandem repeats in unit C of FLO1 of Saccharomyces cerevisiae increases the conformational stability of flocculin under acidic and alkaline conditions. [PDF]

PLoS ONE, 2013
Flocculation is an attractive property for Saccaromyces cerevisiae, which plays important roles in fermentation industry and environmental remediation. The process of flocculation is mediated by a family of cell surface flocculins.
Ee Li, Feng Yue, Qi Chang, Xuena Guo, Xiuping He, Borun Zhang   +5 more
doaj   +1 more source

Global hydrodynamic analysis of the molecular flexibility of galactomannans [PDF]

, 2007
In the past, intrinsic viscosity and sedimentation velocity analyses have been used separately to assess the conformation and flexibility of guar and locust bean gum galactomannans based on worm-like chain and semi-flexible coil models.
Alvaro Ortega, Bohdanecky, Bohdanecky, Clark, David R. Picout, Dea, Gordon A. Morris, Harding, Hearst, Hearst, Jose Garcia de la Torre, Kratky, Patel, Petkowitz, Picout, Picout, Simon B. Ross-Murphy, Stephen E. Harding, Stockmayer, Tanford, Tombs, Trushar R. Patel, Yamakawa   +22 more
core   +1 more source

Automated access to well-defined ionic oligosaccharides [PDF]

, 2020
Ionic polysaccharides are part of many biological events, but lack structural characterisation due to challenging purifications and complex synthesis. Four monosaccharides bearing modifications not found in nature are used for the automated synthesis of ...
Delbianco, M., Grafmüller, A., Schiefelbein, K., Seeberger, P., Tyrikos-Ergas, T., Zhu, Y.   +5 more
core   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Functional Expression and Characterization of the Recombinant N-Acetyl-Glucosamine/N-Acetyl-Galactosamine-Specific Marine Algal Lectin BPL3

Marine Drugs, 2018
Lectins, characterized by their carbohydrate-binding ability, have extensive practical applications. However, their industrial use is limited due to impurity. Thus, quality-controlled production of recombinant lectin is necessary.
Hyun-Ju Hwang, Jin-Woo Han, Gwang Hoon Kim, Jong Won Han   +3 more
doaj   +1 more source

Stereoselective synthesis of a 4-⍺-glucoside of valienamine and its X-ray structure in complex with Streptomyces coelicolor GlgE1-V279S

Scientific Reports, 2021
Glycoside hydrolases (GH) are a large family of hydrolytic enzymes found in all domains of life. As such, they control a plethora of normal and pathogenic biological functions.
Anshupriya Si, Thilina D. Jayasinghe, Radhika Thanvi, Donald R. Ronning, Steven J. Sucheck   +4 more
doaj   +1 more source

An initial event in insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein [PDF]

, 2013
In response to invading microorganisms, insect β-1,3-glucan recognition protein (βGRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease cascades that promote destruction of pathogens by means
Amzel L. M., An C., Barral P., Boraston A. B., Brünger A. T., Buchon N., Cavanagh C., Clore G. M., Cornilescu G., Daisuke Takahashi, David VanderVelde, Delaglio F., Deslandes Y., Fabrick J. A., Fabrick J. A., Goddard T. D., Gottar M., Handa N., Hiromasa Y., Hiromasa Y., Hrmova M., Huaien Dai, Jeffrey A. Fabrick, Jiang H., Kanagawa M., Kim Y. S., Laughton A. M., Lim J. H., Ma C., Matskevich A. A., Michael R. Kanost, Mishima Y., Ochiai M., Okuyama K., Peng J. W., Perkins S. J., Ramaswamy Krishnamoorthi, Roh K. B., Schachman H. K., Takahasi K., Wang Y., Weis W. I., Wiseman T., Wishart D. S., Yasuaki Hiromasa, Young S. H.   +45 more
core   +2 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Sugar-Annulated Oxazoline Ligands: A Novel Pd(II) Complex and Its Application in Allylic Substitution

Molecules, 2016
Two novel carbohydrate-derived pyridyl (PYOX)- and cyclopropyl (CYBOX)-substituted oxazoline ligands were prepared from d-glucosamine hydrochloride and 1,3,4,6-tetra-O-acetyl-2-amino-2-deoxy-β-d-glucopyranose hydrochloride in two steps, respectively. The
Jochen Kraft, Katharina Mill, Thomas Ziegler   +2 more
doaj   +1 more source

Modular hyperthermostable bacterial endo-β-1,4-mannanase: molecular shape, flexibility and temperature-dependent conformational changes. [PDF]

PLoS ONE, 2014
Endo-β-1,4-mannanase from Thermotoga petrophila (TpMan) is a hyperthermostable enzyme that catalyzes the hydrolysis of β-1,4-mannoside linkages in various mannan-containing polysaccharides.
Viviam M da Silva, Francieli Colussi, Mario de Oliveira Neto, Antonio S K Braz, Fabio M Squina, Cristiano L P Oliveira, Cristiano L P Oliveira, Wanius Garcia   +7 more
doaj   +1 more source