Results 51 to 60 of about 420,970 (290)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Conformation-Driven Self-Assembly: From a 1D Metal–Organic Polymer to an Infinite Double Nanotube

, 2019
A novel conformation-driven self-assembly system from a one-dimensional polymer to a metal–organic double nanotube has been developed. DFT calculations indicate that the double nanotube with a syn-conformation of ligands is a thermodynamically favored ...
Junze Cao (6860057), Liang Zhao (94728), Maochun Hong (1453153), Haigang Hao (6860060), Hui Xue (35303)   +4 more
core   +4 more sources

Effects of Altitudinal Gradient on Physicochemical and Rheological Potential of Quinoa Cultivars

Frontiers in Sustainable Food Systems, 2022
The protein, carbohydrate, and fat characteristics of quinoa grains reflect in their techno-functional potential. This aspect has been little studied in quinoa, while some physicochemical and rheological characteristics have been generalized for all ...
Miguel Ángel Garcia-Parra, Miguel Ángel Garcia-Parra, Diego Fernando Roa-Acosta, Jesús Eduardo Bravo-Gomez, Juan Carlos Hernández-Criado, Héctor Samuel Villada-Castillo   +5 more
doaj   +1 more source

Effect of structural modifications of ganglioside GM2 on intra-molecular carbohydrate-to-carbohydrate interaction and enzymatic susceptibility

, 2008
The effect of inter-molecular carbohydrate-to-carbohydrate interaction on basic cell biological processes has been well documented and appreciated. In contrast, very little is known about the intra-molecular carbohydrate-to-carbohydrate interaction.
A. Bernardi, H. Ishida, L. Raimondi, L. Mauri, S. Sonnino, M. Kiso, S. C. Li, Y. T. Li   +7 more
core   +1 more source

In-silico evaluation of carbohydrate–lectin interactions : bridging oligosaccharides and glycomimetics [PDF]

, 2017
Carbohydrates play a vital role in a variety of physiological and pathological processes and, hence, represent an exciting class of molecules for the development of new therapeutic approaches.
Sager, Christoph Philipp
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Protecting Groups in Carbohydrate Chemistry: Influence on Stereoselectivity of Glycosylations

Molecules, 2010
Saccharides are polyhydroxy compounds, and their synthesis requires complex protecting group manipulations. Protecting groups are usually used to temporarily mask a functional group which may interfere with a certain reaction, but protecting groups in ...
Jian Guo, Xin-Shan Ye
doaj   +1 more source

Interaction of Chondroitin and Hyaluronan Glycosaminoglycans with Surfaces of Carboxylated Carbon Nanotubes Studied Using Molecular Dynamics Simulations

Molecules, 2023
Interaction of β-D-glucopyranuronic acid (GlcA), N-acetyl-β-D-glucosamine (GlcNAc), N-acetyl-β-D-galactosamine (GalNAc) and two natural decameric glycosaminoglycans, hyaluronic acid (HA) and Chondroitin (Ch) with carboxylated carbon nanotubes, were ...
Tomasz Panczyk, Wojciech Plazinski, François-Yves Dupradeau, Agnieszka Brzyska, Pawel Wolski   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source