Results 41 to 50 of about 420,970 (290)

Crystal structure of [(2R,3R,4S)-3,4-bis(acetyloxy)-5-iodo-3,4-dihydro-2H-pyran-2-yl]methyl acetate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C12H15IO7, the 3,4-dihydro-2H-pyran ring is in a distorted half-boat conformation with the atom bearing the acetyloxy group adjacent to the C atom bearing the methylacetate group lying 0.633 (6) Å above the plane of the remaining ...
Julio Zukerman-Schpector, Ignez Caracelli, Hélio A. Stefani, Anwar Shamim, Edward R.T. Tiekink   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Orthopaedic health, conformation and longevity in riding horses [PDF]

, 2013
Soundness and longevity of the riding horse play a central role for animal welfare, sport performance and horse owner economy. Routine registration of health traits in horses is rare. Thus, knowledge of genetic variation in health of horses and long term
Jönsson, Lina
core   +1 more source

Human coronavirus HKU1 spike structures reveal the basis for sialoglycan specificity and carbohydrate-promoted conformational changes

Nature Communications
The human coronavirus HKU1 uses both sialoglycoconjugates and the protein transmembrane serine protease 2 (TMPRSS2) as receptors. Carbohydrate binding leads to the spike protein up conformation required for TMPRSS2 binding, an outcome suggesting a ...
Min Jin, Zaky Hassan, Zhijie Li, Ying Liu, Aleksandra Marakhovskaia, Alan H. M. Wong, Adam Forman, Mark Nitz, Michel Gilbert, Hai Yu, Xi Chen, James M. Rini   +11 more
doaj   +1 more source

Mapping Molecular Recognition of β1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus

Microbiology Spectrum, 2021
A multigene polysaccharide utilization locus (PUL) encoding enzymes and surface carbohydrate (glycan)-binding proteins (SGBPs) was recently identified in prominent members of Bacteroidetes in the human gut and characterized in Bacteroides ovatus.
Viviana G. Correia, Filipa Trovão, Benedita A. Pinheiro, Joana L. A. Brás, Lisete M. Silva, Cláudia Nunes, Manuel A. Coimbra, Yan Liu, Ten Feizi, Carlos M. G. A. Fontes, Barbara Mulloy, Wengang Chai, Ana Luísa Carvalho, Angelina S. Palma   +13 more
doaj   +1 more source

Lanthanide-Chelating Carbohydrate Conjugates Are Useful Tools To Characterize Carbohydrate Conformation in Solution and Sensitive Sensors to Detect Carbohydrate–Protein Interactions

, 2016
The increasing interest in the functional versatility of glycan epitopes in cellular glycoconjugates calls for developing sensitive methods to define carbohydrate conformation in solution and to characterize protein–carbohydrate interactions ...
Armando Navarro-Vázquez (1554718), Sabine André (1505140), F. Javier Cañada (1507669), Gema Domínguez (1651849), Álvaro Mallagaray (1797385), Ángeles Canales (1600531), Javier Pérez-Castells (1651846), Hans-Joachim Gabius (107224), M. Álvaro Berbís (1797388), Jesús Jiménez-Barbero (1507663)   +9 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Acetyl α-d-2,3,4-triacetyllyxopyranoside

IUCrData
The structure of the title compound, C13H18O9, has monoclinic (P21) symmetry. It is of interest with respect to stereochemistry and the anomeric effect. Two acetyl subsituents adopt equatorial orientations and two are axial.
Shawn Culver, Jonathan S. Rhoad
doaj   +1 more source

Das Kupfertetramminion, ein empfindliches Reagens für CD-Untersuchungen von Kohlenhydraten

CHIMIA, 1973
The circular dichroism spectra of carbohydrate copper tetrammonia solutions allow to get valuable information about the configuration and conformation of sugars.
Wolfgang Voelter, Hermann Bauer, Gisela Kuhfittig   +2 more
doaj   +1 more source