Defining the recognition elements of Lewis Y-reactive antibodies. [PDF]
Antibody response to carbohydrate antigens is often independent of T cells and the process of affinity/specificity improvement is considered strictly dependent on the germinal centers. Antibodies induced during a T cell-independent type 2 (TI-2) response
Somdutta Saha +4 more
doaj +1 more source
Candidarugosa lipase (CRL) was activated with surfactants (sodium dodecyl sulfate [SDS]) and covalently immobilized onto a nanocomposite (Fe3O4-CS-DAC) fabricated by combining magnetic nanoparticles Fe3O4 with chitosan (CS) using polysaccharide ...
Shushu Wang +5 more
doaj +1 more source
Community sewage sensors towards evaluation of drug use trends: detection of cocaine in wastewater with DNA-directed immobilization aptamer sensors [PDF]
Illicit drug use has a global concern and effective monitoring and interventions are highly required to combat drug abuse. Wastewater-based epidemiology (WBE) is an innovative and cost-effective approach to evaluate community-wide drug use trends ...
Castrignanò, Erika +4 more
core +3 more sources
A multigene polysaccharide utilization locus (PUL) encoding enzymes and surface carbohydrate (glycan)-binding proteins (SGBPs) was recently identified in prominent members of Bacteroidetes in the human gut and characterized in Bacteroides ovatus.
Viviana G. Correia +13 more
doaj +1 more source
An initial event in insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein [PDF]
In response to invading microorganisms, insect β-1,3-glucan recognition protein (βGRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease cascades that promote destruction of pathogens by means
Amzel L. M. +45 more
core +2 more sources
Conformational studies on the N‐linked carbohydrate chain of bromelain [PDF]
1H‐ and 13C‐NMR assignments for the carbohydrate part of the glycopeptide α‐d‐Man‐(1→6)‐[ß‐d‐Xyl‐(1→2)]‐ß‐d‐Man‐(1→4)‐ß‐d‐GlcNAc‐(1→4)‐[α‐l‐Fuc‐(1→3)]‐ß‐d‐ GlcNAc‐(1→N)‐Asn∼, derived from the proteolytic enzyme bromelain (EC 3.4.22.4), have been obtained using homo‐ and heteronuclear correlation spectroscopy, two‐dimensional homonuclear Hartmann‐Hahn ...
Vliegenthart, J.F.G. +5 more
openaire +3 more sources
Crystal structure of [(2R,3R,4S)-3,4-bis(acetyloxy)-5-iodo-3,4-dihydro-2H-pyran-2-yl]methyl acetate
In the title compound, C12H15IO7, the 3,4-dihydro-2H-pyran ring is in a distorted half-boat conformation with the atom bearing the acetyloxy group adjacent to the C atom bearing the methylacetate group lying 0.633 (6) Å above the plane of the remaining ...
Julio Zukerman-Schpector +4 more
doaj +1 more source
Carbohydrate moieties of major histocompatibility complex class I alloantigens are not required for their recognition by T lymphocytes. [PDF]
The ability to generate specific cytotoxic responses using purified major histocompatibility complex (MHC) antigen in liposomes has made it possible to directly assess the importance of class I carbohydrate moieties in T cell recognition of alloantigen ...
Goldstein, SA, Mescher, MF
core
Structure of a Pheromone Receptor-Associated MHC Molecule with an Open and Empty Groove [PDF]
Neurons in the murine vomeronasal organ (VNO) express a family of class Ib major histocompatibility complex (MHC) proteins (M10s) that interact with the V2R class of VNO receptors.
Bjorkman, Pamela J. +3 more
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

