Results 1 to 10 of about 49 (38)

Carbohydrate utilization in Streptococcus thermophilus: characterization of the genes for aldose 1-epimerase (mutarotase) and UDPglucose 4-epimerase [PDF]

open access: greenJournal of Bacteriology, 1990
The complete nucleotide sequences of the genes encoding aldose 1-epimerase (mutarotase) (galM) and UDPglucose 4-epimerase (galE) and flanking regions of Streptococcus thermophilus have been determined. Both genes are located immediately upstream of the S. thermophilus lac operon.
Bert Poolman   +3 more
openalex   +5 more sources

The role of UDP‐glucose epimerase in carbohydrate metabolism of Arabidopsis [PDF]

open access: bronzeThe Plant Journal, 1998
SummaryUridine 5′‐diphospho‐glucose‐4‐epimerase (UDP‐Glc epimerase) catalyses the reversible epimerization of UDP‐galactose and UDP‐glucose. In contrast to bacteria and yeast, expression of the UDP‐Glc epimerase gene in Arabidopsis was found not to be induced by galactose.
Peter Dörmann, Christoph Benning
openalex   +3 more sources

Functional Characterization of the Rice UDP-glucose 4-epimerase 1, OsUGE1: A Potential Role in Cell Wall Carbohydrate Partitioning during Limiting Nitrogen Conditions

open access: goldPLoS ONE, 2014
Plants grown under inadequate mineralized nitrogen (N) levels undergo N and carbon (C) metabolic re-programming which leads to significant changes in both soluble and insoluble carbohydrate profiles. However, relatively little information is available on the genetic factors controlling carbohydrate partitioning during adaptation to N-limitation ...
David Guevara   +4 more
openalex   +5 more sources

RmlC, a C3′ and C5′ Carbohydrate Epimerase, Appears to Operate via an Intermediate with an Unusual Twist Boat Conformation [PDF]

open access: closedJournal of Molecular Biology, 2006
The striking feature of carbohydrates is their constitutional, conformational and configurational diversity. Biology has harnessed this diversity and manipulates carbohydrate residues in a variety of ways, one of which is epimerization. RmlC catalyzes the epimerization of the C3' and C5' positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-
Changjiang Dong   +11 more
openalex   +6 more sources

Computational modeling of the molecular basis for the calcium-dependence of the mannuronan C-5 epimerase AvAlgE6 from Azotobacter vinelandii

open access: yesComputational and Structural Biotechnology Journal, 2023
The mannuronan C-5 epimerases catalyze epimerization of β-d-mannuronic acid to α-l-guluronic acid in alginate polymers. The seven extracellular Azotobacter vinelandii epimerases (AvAlgE1–7) are calcium-dependent, and calcium is essential for the ...
Margrethe Gaardløs   +2 more
doaj   +1 more source

Metabolic mechanism of mannan in a ruminal bacterium, Ruminococcus albus, involving two mannoside phosphorylases and cellobiose 2-epimerase: discovery of a new carbohydrate phosphorylase, β-1,4-mannooligosaccharide phosphorylase.

open access: yesThe Journal of biological chemistry, 2013
Ruminococcus albus is a typical ruminal bacterium digesting cellulose and hemicellulose. Cellobiose 2-epimerase (CE; EC 5.1.3.11), which converts cellobiose to 4-O-β-D-glucosyl-D-mannose, is a particularly unique enzyme in R. albus, but its physiological function is unclear.
Kawahara, Ryosuke   +6 more
openaire   +3 more sources

Protein flexibility drives sugar rotation and high substrate promiscuity in a GDP-sugar 4-epimerase

open access: yesComputational and Structural Biotechnology Journal
UDP-galactose 4-epimerases (Gal4Es) catalyze the inversion of the 4-hydroxyl configuration of a sugar moiety from an NDP-sugar through a three-step process: oxidation, rotation and reduction. Despite extensive biochemical and structural studies, the role
Carlos Josué Alvarez Quispe   +5 more
doaj   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

open access: yesPest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King   +6 more
wiley   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

open access: yesThe FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola   +11 more
wiley   +1 more source

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