Results 1 to 10 of about 10,496 (141)

Carbon-ion Radiotherapy for Colorectal Cancer

Journal of the Anus, Rectum and Colon, 2021
Heavy-ion radiotherapy (RT) is a kind of particle RT, and carbon-ion beam constitutes the primary delivery method of heavy-ion RT. Unlike the conventional photon modalities, particle RT, in particular carbon-ion radiotherapy (CIRT), offers unique ...
Shigeru Yamada, Hirotoshi Takiyama, Yuka Isozaki, Makoto Shinoto, Hirokazu Makishima, Naoyoshi Yamamoto, Hiroshi Tsuji   +6 more
doaj   +4 more sources

The Emerging Role of Carbon-Ion Radiotherapy [PDF]

Frontiers in Oncology, 2016
Carbon-ion radiotherapy (CIRT) has progressed rapidly in technological delivery, indications, and efficacy. Owing to a focused dose distribution in addition to high linear energy transfer and subsequently high relative biological effect, CIRT is uniquely
Daniel K Ebner, Daniel K Ebner, Tadashi eKamada   +2 more
doaj   +3 more sources

FLASH radiotherapy with carbon ion beams [PDF]

Medical Physics, 2021
AbstractFLASH radiotherapy is considered a new potential breakthrough in cancer treatment. Ultra‐high dose rates (>40 Gy/s) have been shown to reduce toxicity in the normal tissue without compromising tumor control, resulting in a widened therapeutic window.
Weber U. A., Scifoni E., Durante M.
openaire   +6 more sources

Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research

Frontiers in Oncology, 2021
Carbon ion radiotherapy (CIRT) is a useful and advanced technique for prostate cancer. This study sought to investigate the clinical efficacy and translational research for prostate cancer with carbon ion radiotherapy.
Xue Chen, Xue Chen, Qi Yu, Qi Yu, Qi Yu, Qi Yu, Ping Li, Shen Fu, Shen Fu, Shen Fu, Shen Fu, Shen Fu   +11 more
doaj   +1 more source

Carbon‐ion radiotherapy for urological cancers

International Journal of Urology, 2022
AbstractCarbon‐ions are charged particles with a high linear energy transfer, and therefore, they make a better dose distribution with greater biological effects on the tumors compared with photons and protons. Since prostate cancer, renal cell carcinoma, and retroperitoneal sarcomas such as liposarcoma and leiomyosarcoma are known to be radioresistant
Hitoshi Ishikawa, Yuichi Hiroshima, Nobuyuki Kanematsu, Taku Inaniwa, Toshiyuki Shirai, Reiko Imai, Hiroyoshi Suzuki, Koichiro Akakura, Masaru Wakatsuki, Tomohiko Ichikawa, Hiroshi Tsuji   +10 more
openaire   +2 more sources

Clinical outcomes using carbon-ion radiotherapy and dose-volume histogram comparison between carbon-ion radiotherapy and photon therapy for T2b-4N0M0 non-small cell lung cancer-A pilot study. [PDF]

PLoS ONE, 2017
The safety and efficacy of carbon-ion radiotherapy for advanced non-small cell lung cancer have not been established. We evaluated the clinical outcomes and dose-volume histogram parameters of carbon-ion radiotherapy compared with photon therapy in T2b ...
Katsuyuki Shirai, Motohiro Kawashima, Jun-Ichi Saitoh, Takanori Abe, Kyohei Fukata, Yuka Shigeta, Daisuke Irie, Shintaro Shiba, Naoko Okano, Tatsuya Ohno, Takashi Nakano   +10 more
doaj   +1 more source

In vitro evaluation of photon and carbon ion radiotherapy in combination with cisplatin in head and neck squamous cell carcinoma cell lines

Frontiers in Oncology, 2023
BackgroundHeavy ion radiotherapy, such as carbon ion radiotherapy (CIRT), has multiple advantages over conventional photon therapy. Cisplatin, as a classic anti-tumor drugs, has been tested and discovered as a photon radiosensitizer in several cell lines,
Xumeng Fang, Xumeng Fang, Xumeng Fang, Pian Sun, Pian Sun, Pian Sun, Yuanli Dong, Yuanli Dong, Yuanli Dong, Yangle Huang, Yangle Huang, Yangle Huang, Jiade Jay Lu, Jiade Jay Lu, Jiade Jay Lu, Lin Kong, Lin Kong, Lin Kong   +17 more
doaj   +1 more source

Functional imaging-guided carbon ion irradiation with simultaneous integrated boost for localized prostate cancer: study protocol for a phase II randomized controlled clinical trial

Trials, 2022
Background Due to the physical dose distribution characteristic of “Bragg peak” and the biological effect as a kind of high linear energy transfer ray, heavy ion therapy has advantages over conventional photon therapy in both efficacy and safety.
Wei Hu, Ping Li, Zhengshan Hong, Xiaomao Guo, Yulei Pei, Zhenshan Zhang, Qing Zhang   +6 more
doaj   +1 more source

Carbon ion radiotherapy for sacral chordoma [PDF]

The British Journal of Radiology, 2011
The National Institute of Radiological Sciences in Chiba, Japan has offered carbon ion radiotherapy (CIRT) since 1994 using carbon ion beams generated by the heavy ion medical accelerator in Chiba (HIMAC). The total number of cases treated with the HIMAC exceeded 5000 in July 2009.
R, Imai, T, Kamada, S, Sugahara, H, Tsuji, H, Tsujii   +4 more
openaire   +2 more sources

Carbon Ion Therapy: A Modern Review of an Emerging Technology

Frontiers in Oncology, 2020
Radiation therapy is one of the most widely used therapies for malignancies. The therapeutic use of heavy ions, such as carbon, has gained significant interest due to advantageous physical and radiobiologic properties compared to photon based therapy. By
Timothy D. Malouff, Anita Mahajan, Sunil Krishnan, Chris Beltran, Danushka S. Seneviratne, Daniel Michael Trifiletti   +5 more
doaj   +1 more source