Results 201 to 210 of about 166,273 (278)

Effectiveness and Mechanism of Cryoablation in the Treatment of Oral Mucosal Melanoma

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Objectives To assess the effectiveness and safety of cryoablation for oral mucosal melanoma (OMM) and explore its underlying mechanisms to provide insights for precision treatment of OMM. Materials and Methods Patients diagnosed with OMM were divided into a cryoablation group and a noncryoablation therapy group.
Zhu You, Tianqi Zhang, Li Dai, Jie Wen, Mingyang Liu, Tengda Zhao, Guozhu Yin, Yihua Wu, Shizhou Zhang   +8 more
wiley   +1 more source

Laparoscopic omentopexy as a spacer for carbon-ion radiotherapy in locally advanced pancreatic cancer. [PDF]

Ann Hepatobiliary Pancreat Surg
Kim SH, Choi SH, Chung MJ, Lee IJ, Koom WS, Kang CM.   +5 more
europepmc   +1 more source

GPR183‐mediated activation of PI3K is a potential biomarker for immunotherapy in lung cancer

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Anti‐PD1 treatment and PI3Kγ inhibition had remarkable therapeutic performance on CD4+ Tcm and CD4+ Tn in lung cancer through potential regulation of PI3K pathway with participation of GPR183. Abstract Background As one of commonly used immune checkpoint inhibition therapies, PD1 monoclonal antibodies exhibit a promising cancer immunotherapy approach ...
Ling Ye, Nannan Zheng, Fangming Liu, Huirong Fu, Yifei Liu, Ying Yang, Ruixue Qi, Duojiao Wu, Lin Shi, Dongli Song   +9 more
wiley   +1 more source

Long-term Efficacy and Safety of Carbon-ion Radiotherapy for Thoracic Chordoma: A Case Report. [PDF]

In Vivo
Irie D, Shiba S, Miyasaka Y, Okamoto M, Yoshimatsu Y, Shibuya K, Kiyohara H, Ohno T.   +7 more
europepmc   +1 more source

Carbon ion radiotherapy at HIMAC-NIRS

Carbon ion radiotherapy at HIMAC-NIRS
In 1994, carbon ion radiotherapy was begun at the NIRS (National Institute of Radiological Sciences) using HIMAC (Heavy-Ion Medical Accelerator in Chiba), which was the world's first heavy ion accelerator complex dedicated to medical use in a hospital environment.
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Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

Drug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal, Akanksha Jain, Ashwini Babu, Chandan Kumar, Madhava B. Mallia   +4 more
wiley   +1 more source

Carbon ion radiotherapy optimization techniques for pancreatic cancer: accounting for the effect of bowel gas variation. [PDF]

Strahlenther Onkol
Sheen C, Lee S, Kim B, Son J, Kim K, Jin H.   +5 more
europepmc   +1 more source

Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan, Run Li, Lei Fu, Jiali Yang, Zhean Zhan   +4 more
wiley   +1 more source

Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma. [PDF]

J Transl Med
Hu W, Huang Q, Chen L, Geng S, Zhang H, Chen H, Liu X, Zhong J, Su F, Shao C, Kong L.   +10 more
europepmc   +1 more source

Clinical advantages of carbon-ion radiotherapy

Clinical advantages of carbon-ion radiotherapy
Carbon-ion radiotherapy(C-ion RT)possesses physical and biological advantages. It was started at NIRS in 1994 using the Heavy Ion Medical Accelerator in Chiba(HIMAC); since then more than 50 protocol studies have been conducted on almost 4000 patients with avariety of tumors.
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