Results 71 to 80 of about 10,882 (190)

Improvement of Escherichia coli production strains by modification of the phosphoenolpyruvate:sugar phosphotransferase system

Microbial Cell Factories, 2005
The application of metabolic engineering in Escherichia coli has resulted in the generation of strains with the capacity to produce metabolites of commercial interest.
Gosset Guillermo
doaj   +1 more source

Identification of the CRE-1 cellulolytic regulon in Neurospora crassa. [PDF]

PLoS ONE, 2011
BACKGROUND: In filamentous ascomycete fungi, the utilization of alternate carbon sources is influenced by the zinc finger transcription factor CreA/CRE-1, which encodes a carbon catabolite repressor protein homologous to Mig1 from Saccharomyces ...
Jianping Sun, N Louise Glass
doaj   +1 more source

A Comprehensive Review on Xylitol Production: Experimental and Theoretical Insights, Research Gaps, and Future Perspectives

Advanced Energy and Sustainability Research, Volume 7, Issue 6, June 2026.
This review integrates chemical and biological xylitol production from upstream to downstream, uniquely combining experimental and theoretical insights to reveal mechanisms, bottlenecks, and future directions for sustainable lignocellulosic xylitol production.
Tanongsak Sukkasem, Pratikkumar Lakhani, Atthapon Srifa   +2 more
wiley   +1 more source

Malate-mediated carbon catabolite repression in bacillus subtilis involves the HPrK/CcpA pathway

, 2011
Most organisms can choose their preferred carbon source from a mixture of nutrients. This process is called carbon catabolite repression. The Gram-positive bacterium Bacillus subtilis uses glucose as the preferred source of carbon and energy.
Le Coq, Dominique, Mehne, Felix M. P., Matthieu Jules, Frederik M. Meyer, Jules, Matthieu, Jens J. Landmann, Boris Görke, Meyer, Frederik M., Jörg Stülke, Landmann, Jens J., Goerke, Boris, Aymerich, Stephane, Dominique Le Coq, Felix M. P. Mehne, Stéphane Aymerich, Stuelke, Joerg   +15 more
core   +1 more source

High‐Yield Production and Cost‐Effective Purification of an Alkali‐Resistant Hexameric Protein A Variant for Antibody Affinity Chromatography

Biotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary We present a scalable method for producing the antibody‐binding ligand Z6AlkC, a six‐repeat, alkali‐resistant Protein A–derived Z domain with a terminal cysteine. The ligand was produced at high yield via extracellular secretion in bioreactors and subsequently purified by high‐productivity ultradiafiltration with low ...
Carolina Mota Natal, Claudia Lacombe, Alexander Zollner, Catarina Domingos, José Mendes, André Nascimento, Ana Margarida Gonçalves Carvalho Dias, Arménio Jorge Moura Barbosa, Cristina Peixoto, Birgit Wiltschi, Alois Jungbauer, Ana Cecília Afonso Roque   +11 more
wiley   +1 more source

Advancing Malic Acid Production of Aspergillus oryzae: Combined Process Optimization and Application of Various Substrates

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1634-1647, June 2026.
ABSTRACT In light of climate change and growing resource scarcity, microbial production of organic acids offers a sustainable alternative to fossil‐based chemical synthesis. In this study, malic acid production by Aspergillus oryzae was optimized through cultivation temperature adjustment and biotin supplementation, while organic acid formation from ...
Lukas Hartmann, Anke Neumann, Dirk Holtmann, Björn Vater, Thomas Hahn, Susanne Zibek, Katrin Ochsenreither   +6 more
wiley   +1 more source

Contribution of the phosphoenolpyruvate:mannose phosphotransferase system to carbon catabolite repression in Lactobacillus pentosus [PDF]

Microbiology, 2001
The role of the Lactobacillus pentosus phosphoenolpyruvate:mannose phosphotransferase system (mannose PTS) in sugar transport and control of sugar utilization was investigated. Growth experiments and measurements of PEP-dependent phosphorylation of sugars, of sugar transport and of catabolic enzyme activity were performed, to compare a wild-type strain
Chaillou, Stéphane, Postma, Pieter, Pouwels, Peter   +2 more
openaire   +4 more sources

Establishment of a Single‐Cell Minimal Medium: A Case Study for Microfluidic Cultivation of Corynebacterium glutamicum

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1648-1660, June 2026.
Conventional bulk media are often unsuitable for single‐cell cultivation and analysis because they provide excess nutrients or lack essential components. Redesigning the medium allows for controlled, defined growth, enabling the development of a robust minimal medium that supports quantitative and reproducible single‐cell analysis across different ...
Judith Wegmann, Matthias Pesch, Juliane Zwoch, Andreas Schmid, Dietrich Kohlheyer, Alexander Grünberger   +5 more
wiley   +1 more source

Salt Stress Induces Imbalanced ADI Pathway Gene Expressions in Pediococcus acidilactici Drives Citrulline Accumulation as an Ethyl Carbamate Precursor in Soy Sauce

Food Bioengineering, Volume 5, Issue 2, Page 171-181, June 2026.
ABSTRACT Citrulline is the main precursor of a carcinogen compound ethyl carbamate (EC) in soy sauce. Accumulation of citrulline is mainly related to metabolism of arginine by Pediococcus acidilactici via the arginine deiminase (ADI) pathway during soy sauce fermentation.
Xiaodie Chen, Jiran Zhang, Haoran Chen, Fang Fang   +3 more
wiley   +1 more source

A Co-Fermentation Strategy from Corncob Hydrolysate to Enhance Simultaneous Co-Production of Lactic Acid and Ethanol

Fermentation
Efficient co-utilization of mixed sugars from lignocellulosic hydrolysates is often hindered by carbon catabolite repression and pretreatment-derived inhibitors. In this study, a co-fermentation strategy using Saccharomyces cerevisiae (S. cerevisiae) and
Xiaona Wang, Yongsheng Li, Yuanchun Zhang, Yuanyuan Ren, Hongzhi Ma, Jianguo Liu, Qunhui Wang   +6 more
doaj   +1 more source