Results 201 to 210 of about 5,822,485 (294)

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

Treatment Planning Comparison of Gantry-based and Fixed Beams for the Treatment of Liver Tumors With Carbon Ion Therapy. [PDF]

In Vivo
Miyasaka Y, Lee SH, Souda H, Kaneko T, Hagiwara Y, Chai H, Ishizawa M, Sato H, Iwai T.   +8 more
europepmc   +1 more source

Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon-ion therapy. [PDF]

J Appl Clin Med Phys, 2020
Wei K, Xu Z, Mao R, Zhao Z, Zhao T, She Q, Kang X, Wang J, Li S, Li M, Song K, Yang H, Duan L.   +12 more
europepmc   +1 more source

Combination of ^99mTc-Labeled PSMA-SPECT/CT and Diffusion-Weighted MRI in the Prediction of Early Response After Carbon Ion Therapy in Prostate Cancer: A Non-Randomized Prospective Pilot Study. [PDF]

Cancer Manag Res, 2021
Li P, Liu C, Wu S, Deng L, Zhang G, Cai X, Hu S, Cheng J, Xu X, Wu B, Guo X, Zhang Y, Fu S, Zhang Q.   +13 more
europepmc   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Potential Benefits of Combining Proton or Carbon Ion Therapy with DNA Damage Repair Inhibitors. [PDF]

Cells
Rødland GE, Temelie M, Eek Mariampillai A, Hauge S, Gilbert A, Chevalier F, Savu DI, Syljuåsen RG.   +7 more
europepmc   +1 more source

EXPERIMENTAL REALIZATION OF DYNAMIC CARBON ION ARC THERAPY AT A CLINICAL CARBON ION THERAPY CENTER

International Journal of Particle Therapy
Lennart Volz, Zixin He, Ahmad El-Beit, Cosimo Galeone, Marco Donetti, Marco Durante, Christian Graeff   +6 more
openaire   +1 more source

Status of a Carbon-Ion Therapy Facility and Development for Advanced Treatment

Over 3000 cancer patients have already been treated with 140- to 400-MeV/n carbon beams produced by the heavy ion medical accelerator in Chiba (HIMAC) at the National Institute of Radiological Sciences (NIRS) since 1994.
451393, 451392, 451395, 大野 由美子, 451394, Mizuno, Hideyuki, 451391, 451390, 松藤 成弘, Inaniwa, Taku, Minohara, Shinichi, Satou, Yukio, Torikoshi, Masami, Takada, Eiichi, 451389, 451386, 福村 明史, 451385, 451388, 高田 栄一, 451387, 451382, 451381, 451384, 451383, 451380, Kase, Yuuki, Satou, Shinji, 村松 正幸, 佐藤 幸夫, 金澤 光隆, 小森 雅孝, 451379, 451378, 451375, 451374, 451377, 451376, 鳥飼 幸太, 稲庭 拓, Yamada, Satoru, 水野 秀之, 岩田 佳之, Komori, Masataka, Kanazawa, Mitsutaka, Fukumura, Akifumi, 金井 達明, Kitagawa, Atsushi, 北川 敦志, Torikai, Kota, 加瀬 優紀, 451397, 451396, 451398, 451351, 451350, Noda, Kouji, 藤田 敬, Kanai, Tatsuaki, 451349, 蓑原 伸一, Furukawa, Takuji, Matsufuji, Naruhiro, 佐藤 眞二, Kanematsu, Nobuyuki, Muramatsu, Masayuki, Fujita, Takashi, 野田 耕司, 451371, 451370, 451373, 村上 健, 451372, 兼松 伸幸, Murakami, Takeshi, 取越 正己, 山田 聰, 451368, Iwata, Yoshiyuki, Ohno, Yumiko, 451367, 451369, 451364, 451363, 451366, 451365, 451360, Yonai, Shunsuke, 451362, 451361, 米内 俊祐, 古川 卓司, 451357, 451356, 451359, 451358, 451353, 451352, 451355, 451354   +99 more
core  

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

Advanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li, Kai Su, Ruiwei Hu, Ke Gao, Yuanjie Liu, Lu Zhang, Ningke Fan, Yirong Chen, Wei Cheng, Shijia Ding, Haiping Wu   +10 more
wiley   +1 more source

Commissioning and Validation of CT Number to SPR Calibration in Carbon Ion Therapy Facility. [PDF]

Int J Part Ther
Miyasaka Y, Kanai T, Souda H, Yamazawa Y, Lee SH, Chai H, Sato H, Iwai T.   +7 more
europepmc   +1 more source