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Irradiation-Induced Changes in the Immunogenicity of Lung Cancer Cell Lines: Based on Comparison of X-rays and Carbon Ions [PDF]

open access: yesFrontiers in Public Health, 2021
Increasing the immunogenicity of tumors is considered to be an effective means to improve the synergistic immune effect of radiotherapy. Carbon ions have become ideal radiation for combined immunotherapy due to their particular radiobiological advantages.
Juntao Ran   +7 more
doaj   +2 more sources

Role of Oxidative Stress Signaling, Nrf2, on Survival and Stemness of Human Adipose-Derived Stem Cells Exposed to X-rays, Protons and Carbon Ions [PDF]

open access: yesAntioxidants
Some cancers have a poor prognosis and often lead to local recurrence because they are resistant to available treatments, e.g., glioblastoma. Attempts have been made to increase the sensitivity of resistant tumors by targeting pathways involved in the ...
Mira Hammad   +4 more
doaj   +2 more sources

Discriminative detection of laser-accelerated multi-MeV carbon ions utilizing solid state nuclear track detectors [PDF]

open access: yesScientific Reports, 2021
A new diagnosis method for the discriminative detection of laser-accelerated multi-MeV carbon ions from background oxygen ions utilizing solid-state nuclear track detectors (SSNTDs) is proposed. The idea is to combine two kinds of SSNTDs having different
Takamasa Hihara   +10 more
doaj   +2 more sources

NF-κB in the Radiation Response of A549 Non-Small Cell Lung Cancer Cells to X-rays and Carbon Ions under Hypoxia. [PDF]

open access: goldInt J Mol Sci
Nisar H   +8 more
europepmc   +3 more sources

Accelerators, Gantries, Magnets and Imaging Systems for Particle Beam Therapy: Recent Status and Prospects for Improvement

open access: yesFrontiers in Oncology, 2022
The paper begins by emphasizing the clinical and commercial importance of proton or other charged particle such as carbon ion therapy, refers to the manufacturers of such systems of which more than 120 are installed or under construction worldwide by ...
Edward W. Collings   +3 more
doaj   +1 more source

The Effects of Combined Exposure to Simulated Microgravity, Ionizing Radiation, and Cortisol on the In Vitro Wound Healing Process

open access: yesCells, 2023
Human spaceflight is associated with several health-related issues as a result of long-term exposure to microgravity, ionizing radiation, and higher levels of psychological stress.
Wilhelmina E. Radstake   +19 more
doaj   +1 more source

Radioactive Beams for Image-Guided Particle Therapy: The BARB Experiment at GSI

open access: yesFrontiers in Oncology, 2021
Several techniques are under development for image-guidance in particle therapy. Positron (β+) emission tomography (PET) is in use since many years, because accelerated ions generate positron-emitting isotopes by nuclear fragmentation in the human body ...
Daria Boscolo   +73 more
doaj   +1 more source

Application of Carbon Quantum dot Fluorescent Materials in Metal Ions Detection [PDF]

open access: yesE3S Web of Conferences, 2021
The research situation of the application of carbon quantum dot fluorescent materials to the detection of metal ions, including the current research status and preface of recent years, and development trends are summarized.
Gao Yan   +5 more
doaj   +1 more source

In Vitro Effects of Photon Beam and Carbon Ion Radiotherapy on the Perineural Invasion of Two Cell Lines of Neurotropic Tumours

open access: yesLife, 2023
Primary mucosal melanoma (PMM) and pancreatic ductal adenocarcinoma (PDAC) are two aggressive malignancies, characterized by intrinsic radio-chemoresistance and neurotropism, a histological feature resulting in frequent perineural invasion (PNI ...
Alexandra Charalampopoulou   +10 more
doaj   +1 more source

Factors released by low and high-LET irradiated fibroblasts modulate migration and invasiveness of pancreatic cancer cells

open access: yesFrontiers in Oncology, 2022
IntroductionRadiotherapy represents a major treatment option for patients with pancreatic cancer, however, its benefits remain limited also due to the ability of cancer cells to migrate to the surrounding tissues. Low-LET ionizing radiation is well known
Alexandra Charalampopoulou   +7 more
doaj   +1 more source

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