Results 51 to 60 of about 840,010 (348)

Performance of the reconstruction algorithms of the FIRST experiment pixel sensors vertex detector [PDF]

, 2014
Hadrontherapy treatments use charged particles (e.g. protons and carbon ions) to treat tumors. During a therapeutic treatment with carbon ions, the beam undergoes nuclear fragmentation processes giving rise to significant yields of secondary charged ...
Abou-Haidar, Z., Agodi, C., Alvarez, M.A.G., Baudot, J., Cortés Giraldo, Miguel Antonio, Finck, C., Gallardo Fuentes, María Isabel, Juliani, D., Quesada Molina, José Manuel, Rescigno, R., Spiriti, E., Younis, H.   +11 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Carbon ion radiotherapy for sacral chordoma [PDF]

The British Journal of Radiology, 2011
The National Institute of Radiological Sciences in Chiba, Japan has offered carbon ion radiotherapy (CIRT) since 1994 using carbon ion beams generated by the heavy ion medical accelerator in Chiba (HIMAC). The total number of cases treated with the HIMAC exceeded 5000 in July 2009.
R, Imai, T, Kamada, S, Sugahara, H, Tsuji, H, Tsujii   +4 more
openaire   +2 more sources

Carbon-ion Radiotherapy for Colorectal Cancer

Journal of the Anus, Rectum and Colon, 2021
Heavy-ion radiotherapy (RT) is a kind of particle RT, and carbon-ion beam constitutes the primary delivery method of heavy-ion RT. Unlike the conventional photon modalities, particle RT, in particular carbon-ion radiotherapy (CIRT), offers unique physical and biological advantages.
Shigeru Yamada, Hirotoshi Takiyama, Yuka Isozaki, Makoto Shinoto, Hirokazu Makishima, Naoyoshi Yamamoto, Hiroshi Tsuji   +6 more
openaire   +4 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Mini-TEPC Microdosimetric Study of Carbon Ion Therapeutic Beams at CNAO

EPJ Web of Conferences, 2017
Mono-energetic carbon ion scanning beams of 195.2 MeV/u at the Italian National Centre for Oncological Hadrontherapy (CNAO) have been used to study the microdosimetric features of an “active” carbon ion beam used in hadrontherapy.
Conte V., Colautti P., Chiriotti S., Moros D., Ciocca M., Mairani A.   +5 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Synthesis of Up-Conversion Fluorescence N-Doped Carbon Dots with High Selectivity and Sensitivity for Detection of Cu²⁺ Ions

Crystals, 2023
Carbon dots have drawn extensive attention in the detection of metal ions with good stability, excellent biocompatibility and low toxicity. Meanwhile, the quantum yield, response rate and the detection mechanism for Cu2+ ions are vital to their ...
Yuanyuan Xiong, Mengxiao Chen, Zhen Mao, Yiqing Deng, Jing He, Huaixuan Mu, Peini Li, Wangcai Zou, Qiang Zhao   +8 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Factors Influencing the Biological Effects of FLASH Irradiation

Antioxidants
Among the methods for increasing the specificity of tumor radiotherapy, FLASH radiotherapy (FLASH-RT) stands out, having recently entered clinical trials.
Sergey Igorevich Glukhov, Elena Ananievna Kuznetsova, Sergey Vsevolodovich Akulinichev   +2 more
doaj   +1 more source