Results 131 to 140 of about 70,737 (245)

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Water‐Derived Radical Species Initiate Six‐Electron Oxidation of Cyclic Ketones in Microdroplets

open access: yesAngewandte Chemie, EarlyView.
Spontaneous six‐electron oxidation of cyclic ketones to yield dicarboxylic acids/keto acids is achieved in ethanol microdroplets containing about 2% water under ambient conditions without any metal salts, acids, or oxidants. Mechanistic studies show that trace amounts of water and molecular oxygen serve as active oxidants in this transformation ...
Muhammad Mujahid Ali   +3 more
wiley   +2 more sources

Metabolic controls on the carbon isotope fractionations of bacterial fermentation. [PDF]

open access: yesProc Natl Acad Sci U S A
Mueller EP   +4 more
europepmc   +1 more source

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

open access: yesAngewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog   +5 more
wiley   +2 more sources

Characterization of trace element impurities and carbon isotope delta in HIPC-1, a high-purity graphite certified reference material. [PDF]

open access: yesAnal Bioanal Chem
Chartrand MMG   +8 more
europepmc   +1 more source

Characterization of vanillin carbon isotope delta reference materials. [PDF]

open access: yesAnal Bioanal Chem, 2022
Chartrand MMG   +6 more
europepmc   +1 more source

Enriched and Sustained Oxygen Vacancies in Amorphous NiWOx Enhance and Stabilize Urea Electrooxidation

open access: yesAngewandte Chemie, EarlyView.
We propose an “amorphous oxygen mechanism (AOM)” for urea electrooxidation on amorphous NiWOx with tunable Ov, which achieves robust UOR activity and stability simultaneously. The “amorphous oxygen” in NiWOx prefers to escape during the UOR, in situ generating and stabilizing Ov, which thermodynamically promotes the reaction.
Yinuo Wang   +9 more
wiley   +2 more sources

Vanadium-Mediated Carbon Isotope Exchange of Terminal Alkenes. [PDF]

open access: yesJ Am Chem Soc
Krivovicheva V   +5 more
europepmc   +1 more source

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