Results 101 to 110 of about 77,334 (297)

CARBONIC ANHYDRASE IN Plasmodium falciparum: A USEFUL TARGET FOR ANTIMALARIAL DRUG DESIGNING AND MALARIA blocking TRANSMISSION COMPOUNDS

open access: yesVitae, 2010
Carbonic anhydrase is a metalloenzyme that catalyzes the reversible conversion of CO2 to bicarbonate, an essential metabolic component used by the malaria parasites for de novo synthesis of pyrimidines and the exflagelation of gametocytes inside the ...
Carlos D. AGUDELO R.   +2 more
doaj  

Histochemical detection of carbonic anhydrase with diemthylaminonaphthalene-5-sulfonamide.

open access: yes, 1979
A new specific method for the detection of carbonic anhydrase, EC 4.2.1.1, in tissues is described. The reaction of carbonic anhydrase with dimethylaminonaphthalene-5-sulfonamide (DNSA) forms a highly fluorescent complex.
P R Siegmund, C Pochhammer, P Dietsch
core   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

open access: yesSmart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu   +7 more
wiley   +1 more source

Anticancer evaluation of Myo-inositol through carbonic anhydrase IV inhibition activity: A spectroscopic, quantum computational, topological, drug-likeness and in-silico molecular docking studies

open access: yesResults in Chemistry
Numerous inositol isomers, particularly myo-inositol, are beneficial in the treatment of polycystic ovary syndrome, diabetes, anxiety, and depression. This study established that myo-inositol has the potential to be utilized as a carbonic anhydrase IV ...
K. Rajkumar   +6 more
doaj   +1 more source

The immunohistolocalization of carbonic anhydrase in rodent tissues.

open access: yes, 1979
Carbonic anhydrase has been localized with an immunoenzyme bridge technique in the following sites in paraffin sections of fixed rodent tissues: gastric parietal cells, the brush border of enterocytes in the small intestine, superficial nongoblet cells ...
R E Tashian, S S Spicer, P J Stoward
core   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin   +11 more
wiley   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

open access: yesAllergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza   +16 more
wiley   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin   +30 more
wiley   +1 more source

Localization of human muscle carbonic anhydrase isozymes using immunofluorescence.

open access: yes, 1984
Human muscle sections were examined for the presence of carbonic anhydrase using fluorescent second antibody and antisera specific for the three isozymes, carbonic anhydrase I (CAI), carbonic anhydrase II (CAII), and carbonic anhydrase (CAIII).
S Moyle, S Jeffery, N D Carter
core   +1 more source

Intraluminal stent removal after Paul glaucoma implant surgery: Intraocular pressure reduction and safety outcomes

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the outcomes of intraluminal stent removal from the Paul glaucoma implant (PGI). Methods A retrospective observational study of all cases undergoing PGI stent removal from August 2022 to August 2025 at a single Danish tertiary centre. Primary endpoints were intraocular pressure (IOP) and IOP‐lowering medications.
Anne Studsgaard   +2 more
wiley   +1 more source

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