Results 111 to 120 of about 77,334 (297)

Neovascular glaucoma at a tertiary Centre in Finland, 2008–2024: A retrospective cohort study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Neovascular glaucoma (NVG) is a refractory secondary glaucoma, yet longitudinal outcome data remain limited. This study reports its aetiologies, treatments and outcomes. Methods Patients with NVG were identified through electronic medical record review.
Gilbert Simons, Mikael von Fersen, Paula Summanen, Mika Harju   +3 more
wiley   +1 more source

Evaluation of Benzenesulfonamide Derivatives; Quinazoline and Sulfonamide Selectively Targeting Carbonic Anhydrase XII for Tumor Microenvironment Modulation in Human Breast Cancer Cells

Al-Mustansiriyah Journal of Pharmaceutical Sciences
Tumor cells evolve adaptive mechanisms to function optimally within an acidic microenvironment. This adaptation is driven by the enhanced metabolic activity of tumors, which frequently results in acidosis and hypoxia.
HIBA NABIL MIRAN, GHAITH ALI JASIM, TAREQ HAFDHI ABIDTAWFEEQ, AMMAR A. IBRAHIM AL-AZZAWI   +3 more
doaj   +1 more source

Experiment: Elevated CO2 levels affect the activity of nitrate reductase and carbonic anhydrase in the calcifying rhodophyte Corallina officinalis (Fig. 2: Nutrients)

, 2014
Experiment: Elevated CO2 levels affect the activity of nitrate reductase and carbonic anhydrase in the calcifying rhodophyte Corallina officinalis (Fig.3: Temperature and ...
Hofmann, Laurie C, Laurie C Hofmann (8006903)   +1 more
core   +1 more source

Predictors of visual acuity, intraocular pressure and pain in neovascular glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify factors associated with best‐corrected visual acuity (BCVA), intraocular pressure (IOP) and ocular pain in neovascular glaucoma (NVG). Methods The retrospective cohort included all patients diagnosed with NVG during 2008–2024 at Helsinki University Hospital, Finland. Linear mixed‐effects models used pre‐specified covariates,
Gilbert Simons, Mikael von Fersen, Alexandra Dahlberg, Ville Vartiainen, Paula Summanen, Mika Harju   +5 more
wiley   +1 more source

CARBONIC ANHYDRASE AS A MARKER OF OSTEOCLAST ACTIVITY IN THE REPAIR ZONE OF LONG BONE FRACTURE

Acta Biomedica Scientifica, 2012
In an experimental model of long bone fractures studied osteoclastic activity in the fracture zone. We used histological staining methods and histochemical staining with antibodies to carbonic anhydrase type II.
I. A. Shurygina, M. G. Shurygin, L. V. Rodionova, V. Ph. Lebedev, N. N. Dremina   +4 more
doaj  

Investigation of Bacterial Carbonic Anhydrase Stability

, 2020
The purpose of this study was to investigate the stability of Bartonella henselae carbonic anhydrase in an effort to design screening methods for potential inhibitors.
Sutaria, Yatri
core  

Activity of carbonic anhydrase inhibitors in breast cancer models. [PDF]

, 2016
Evaluation of carbonic anhydrase inhibitors activity in breast cancer 2D and 3D ...
Želvytė, Aušra,
core  

Trends in glaucoma diagnosis and medical management in Germany: A nationwide claims data analysis over 10 years

Acta Ophthalmologica, EarlyView.
Abstract Purpose Analysing longitudinal trends in recorded diagnosis and medical management of glaucoma in Germany over a 10‐year period. Methods A retrospective cohort study using nationwide outpatient claims and prescription data from the German statutory health insurance system.
Somar M. Hasan, Leonore Bovy, Maike Below, Kerstin Klimke, Alexander K. Schuster, Jan Darius Unterlauft, Carl Erb, Argyrios Chronopoulos, Robert P. Finger   +8 more
wiley   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source