Results 11 to 20 of about 63,059 (304)

Identification of anti-cyanobacterial leads targeting carbonic anhydrase from phytochemical database using in silico approach

BioTechnologia, 2023
In cyanobacteria, carbonic anhydrase (zinc metalloenzyme) is a major enzyme that converts CO 2 to HCO 3- main¬taining the carbon concentration around the vicinity of RuBisCo, leading to cyanobacterial biomass generation.
Archana Padhiary, Showkat A. Mir, Sheary S. Tete, Iswar Baitharu, Binata Nayak   +4 more
doaj   +2 more sources

5-(Sulfamoyl)thien-2-yl 1,3-oxazole inhibitors of carbonic anhydrase II with hydrophilic periphery [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Hydrophilic derivatives of an earlier described series of carbonic anhydrase inhibitors have been designed, prepared and profiled against a panel of carbonic anhydrase isoforms, including the glaucoma-related hCA II.
Stanislav Kalinin, Alexander Kovalenko, Annika Valtari, Alessio Nocentini, Maxim Gureev, Arto Urtti, Mikhail Korsakov, Claudiu T. Supuran, Mikhail Krasavin   +8 more
doaj   +2 more sources

Renal carbonic anhydrase

American Journal of Physiology-Renal Physiology, 1982
Carbonic anhydrase is a zinc metalloenzyme widely distributed throughout the tissues of the body. This enzyme exists in a number of isozymic forms in most mammalian species.
R. E. Bulger, D. C. Dobyan
core   +3 more sources

Update and critical appraisal of combined timolol and carbonic anhydrase inhibitors and the effect on ocular blood flow in glaucoma patients

Clinical Ophthalmology, 2010
Adam M Moss, Alon Harris, Brent Siesky, Deepam Rusia, Kathleen M Williamson, Yochai ShoshaniDepartment of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USAAbstract: Topical hypotensive therapy with both timolol and carbonic
Adam M Moss, Alon Harris, Brent Siesky, et al   +3 more
doaj   +1 more source

Strong topical steroid, NSAID, and carbonic anhydrase inhibitor cocktail for treatment of cystoid macular edema

International Medical Case Reports Journal, 2015
Masumi G Asahi, Gabriela L Bobarnac Dogaru, Spencer M Onishi, Ron P GallemoreRetina Macula Institute, Torrance, CA, USA Purpose: To report the combination cocktail of strong steroid, non-steroidal anti-inflammatory drug (NSAID), and carbonic anhydrase ...
Asahi MG, Bobarnac Dogaru GL, Onishi SM, Gallemore RP   +3 more
doaj   +1 more source

Quantitative Characterization of the Chemical Space Governed by Human Carbonic Anhydrases and selenium-containing derivatives of solfonamides [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2022
Due to the fact that different isoforms of carbonic anhydrase play distinct physiological roles, their diseases/disorders involvement are different as well.
Behnam Rasti
doaj   +1 more source

Carbon sink of microalgae in karst lakes under the influence of the extracellular of carbonic anhydrase

Carsologica Sinica, 2022
Carbonic anhydrase is a metal enzyme which contains Zn. It has the characteristics of catalyzing the mutual conversion between CO2 and HCO3− with high efficiency and specificity.
Haitao LI, Yanyou WU, Bing FU
doaj   +1 more source

Circadian miR-218-5p targets gene CA2 to regulate uterine carbonic anhydrase activity during egg shell calcification

Poultry Science, 2022
: MicroRNAs (miRNAs) are involved in regulating the circadian clock. In our previous work, miR-218-5p was found to be a circadian miRNA in the chicken uterus, but its role in the eggshell formation process was not clear.
Xiaxia Du, Zhifu Cui, Zifan Ning, Xun Deng, Felix Kwame Amevor, Gang Shu, Xiaoqi Wang, Zhichao Zhang, Yaofu Tian, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang, Xiaoling Zhao   +13 more
doaj   +1 more source

Carbonic Anhydrase II Activators in Osteopetrosis Treatment: A Review

Current Issues in Molecular Biology, 2023
Osteopetrosis is a rare hereditary illness generated by failure in osteoclasts resulting in elevated bone densities. Patients with osteopetrosis possess several complications, like dental caries, earlier teeth loss, delayed eruption, malformed crowns and
Zikra Alkhayal, Zakia Shinwari, Ameera Gaafar, Ayodele Alaiya   +3 more
doaj   +1 more source

Collateral Changes in Cell Physiology Associated with ADC-7 β-Lactamase Expression in Acinetobacter baumannii

Microbiology Spectrum, 2023
The ADC (AmpC) β-lactamase is universally present in the Acinetobacter baumannii chromosome, suggesting it may have a yet-to-be-identified cellular function. Using peptidoglycan composition analysis, we show that overexpressing the ADC-7 β-lactamase in A.
Jennifer M. Colquhoun, Marjan Farokhyfar, Alexander C. Anderson, Christopher R. Bethel, Robert A. Bonomo, Anthony J. Clarke, Philip N. Rather   +6 more
doaj   +1 more source