Results 51 to 60 of about 77,334 (297)
Sains NaturalThis article explores the interaction of Coumarin compounds and their derivatives obtained from natural extracts with Carbonic anhydrase II protein in inhibiting Glaucoma computationally.
Rismi Verawati +2 more
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Kidney and Blood Pressure Research, 1987 The purpose of the present review is to describe the use of carbonic anhydrase inhibitors in clinical medicine and renal physiology. We first describe the localization of carbonic anhydrase within the kidney and then discuss evidence for its role in renal acidification and NaCl absorption.
P A, Preisig, R D, Toto, R J, Alpern
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Characterization of Carbonic Anhydrase In Vivo Using Magnetic Resonance Spectroscopy
, 2020 Carbonic anhydrase is a ubiquitous metalloenzyme that catalyzes the reversible interconversion of CO2/HCO3−. Equilibrium of these species is maintained by the action of carbonic anhydrase.
Jun Shen, Jyoti Singh Tomar
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Advanced Science, EarlyView.MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo +6 more
wiley +1 more source
Polyamines and α-Carbonic Anhydrases [PDF]
Molecules, 2016 Natural products represent a straightforward source for molecular structures bearing a vast array of chemical features and potentially useful for biomedical purposes. Recent examples of this type include the discovery of the coumarins and the polyamine natural products as atypical chemotypes for the inhibition of the metalloenzymes carbonic anhydrases (
SCOZZAFAVA, ANDREA +2 more
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Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Carbonic anhydrase inhibitor attenuates ischemia-reperfusion induced acute lung injury.
PLoS ONE, 2017 Ischemia-reperfusion (IR)-induced acute lung injury (ALI) is implicated in several clinical conditions including lung transplantation, cardiopulmonary bypass surgery, re-expansion of collapsed lung from pneumothorax or pleural effusion and etc.
Chou-Chin Lan +4 more
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CARBONIC ANHYDRASE IN MOLLUISCS
The Biological Bulletin, 1948 Carbonic anhydrase has been demonstrated in the mantle tissues and body fluids of most of 12 species of pelecypods and 8 species of gastropods.
Freeman, John A, Wilbur, Karl M
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Advanced Science, EarlyView.This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei +17 more
wiley +1 more source
Inorganic carbon acquisition in Palmaria palmata (Rhodophyta) [PDF]
, 2010 PhDDIC acquisition mechanisms and the use of DIC in photosynthesis were examined in the temperate red macroalga, Palmaria palmata (Linnaeus) O. Kuntze.
Hill, Gregg
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