Results 61 to 70 of about 63,059 (304)

Catecholamine-induced vasoconstriction is sensitive to carbonic anhydrase I activation

Brazilian Journal of Medical and Biological Research, 2001
We studied the relationship between alpha- and beta-adrenergic agonists and the activity of carbonic anhydrase I and II in erythrocyte, clinical and vessel studies. Kinetic studies were performed.
Puscas I., Coltau M., Gilau L., Pasca R., Domuta G., Baican M., Hecht A.   +6 more
doaj  

A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II

Biomolecules, 2020
Fragment screening is a powerful tool to identify and characterize binding pockets in proteins. We herein present the results of a proof-of-concept screening campaign of a versatile 96-entry fragment library from our laboratory against the drug target ...
Steffen Glöckner, Andreas Heine, Gerhard Klebe   +2 more
doaj   +1 more source

Carbonic anhydrase traced by cadmium isotope fractionations in Archean to Holocene stromatolitic carbonates

Communications Earth & Environment
Stromatolites record interactions of the biosphere, atmosphere, and hydrosphere. The evolution of C-fixation via diverse metabolisms is linked to metal availability for enzymes such as carbonic anhydrase.
Simon V. Hohl, Sebastian Viehmann, Philipp Gleissner, Ashley N. Martin, Martin J. Van Kranendonk   +4 more
doaj   +1 more source

Immobilization of Carbonic Anhydrase for Biomimetic CO₂ Capture

Chemical Engineering Transactions, 2013
Novel post-combustion treatments include carbon capture and sequestration processes based on biomimetic strategies. These strategies include CO2 absorption into aqueous solution assisted by enzyme catalysis. Carbonic anhydrase catalyses CO2 hydration and
M.E. Russo, S. Scialla, V. De Luca, C. Capasso, G. Olivieri, A. Marzocchella   +5 more
doaj   +1 more source

A Selective Phenyl Azo Acetate Substrate for Enhanced Carbonic Anhydrase Functional Analysis. [PDF]

Anal Sci Adv
ABSTRACT Carbon dioxide (CO2) sequestration is a key strategy for mitigating climate change, and biocatalytic approaches offer sustainable, cost‐effective alternatives to chemical and physical methods. Carbonic anhydrases (CAs) efficiently catalyse the reversible hydration of CO2 to bicarbonate, yet their large‐scale application is constrained by ...
Babinskas J, Matijošytė I.
europepmc   +2 more sources

Affinity to some inhibitors of human carbonic anhydrase-1 and bovine carbonic anhydrase

, 1996
The carbonic anhydrase Isoenzymes employed here have been purifield in high yields by affinity chromatograpy using different affinity gels(Sepharose4B-L-tyrosine-Benzensulfonamide).
Kufrevioglu, OI, ARSLAN, O
core   +1 more source

Carbonic Anhydrase Inhibitors

Kidney and Blood Pressure Research, 1987
The purpose of the present review is to describe the use of carbonic anhydrase inhibitors in clinical medicine and renal physiology. We first describe the localization of carbonic anhydrase within the kidney and then discuss evidence for its role in renal acidification and NaCl absorption.
P A, Preisig, R D, Toto, R J, Alpern
openaire   +2 more sources

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

Annals of Neurology, EarlyView.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale, Arkadiusz Nawrocki, Johanne J. Korsbæk, Nadja S. Hansen, Fabian Foettinger, Nik Krajnc, Mathias J. Norvig, Niclas L. Eriksen, Stefan Macher, Berthold Pemp, Connar S.J. Westgate, Christian B. Pedersen, Frantz R. Poulsen, Sune Munthe, Gabriel Bsteh, Martin R. Larsen, Rigmor H. Jensen, Dagmar Beier   +17 more
wiley   +1 more source

Prospects for the application of inhibitors of carbonic anhydrase isoforms IX and XII in oncology

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова
Human carbonic anhydrase isoforms IX and XII play a key role in maintaining acid-base balance in solid tumors, creating a favorable microenvironment for the growth, invasion and metastasis of tumor cells.
S. А. Kalinin, Т. V. Sharonova, А. М. Malkova, S. V. Ageev, К. N. Semenov, V. V. Sharoyko   +5 more
doaj   +1 more source

CARBONIC ANHYDRASE IN GREEN PLANTS

, 1950
Carbonic anhydrase was found in leaf extracts prepared from 19 of 22 land and aquatic plant species examined. The most active preparations were obtained from Spinacia oleracea L., Tetragonia expansa Thunb., Tropaeolum majus L., and Sambucus canadensis L.
K. A. Clendenning, E. R. Waygood
core   +1 more source