We extend a widely used C3‐photosynthesis model to account for various photorespiratory bypasses, thereby, providing a useful resource and framework that enforces future novel bypass work and scrutinize if the results go counter to theory. Our model analyses show that of the 17 published bypass pathways, full‐decarboxylating bypasses (that have been ...
Xinyou Yin +3 more
wiley +1 more source
Depression and Anxiety After Topical Carbonic Anhydrase Inhibitors. [PDF]
Elhusseiny AM, Alzein AF, Medeiros FA.
europepmc +1 more source
Hypoxia‐Driven CA2 Promotes Trophoblast Dysfunction in Preeclampsia
CA2 is upregulated in preeclampsia and impairs trophoblast function by suppressing VEGFA under hypoxia/HIF‐1α signaling. LNP‐mediated CA2 silencing improves placental structure and fetal outcomes, highlighting CA2 as a promising therapeutic target for PE.
Lujiao Chen +7 more
wiley +1 more source
Sulfonamide-Based 2-Amino-1,3,4-Oxadiazole Derivatives as Dual Cholinesterase and Carbonic Anhydrase Inhibitors: Design, Synthesis, Kinetic Characterization, Molecular Modeling, and ADMET Evaluation. [PDF]
Arslan Karahan G +4 more
europepmc +1 more source
Sulfonamide–thiazolidinone hybrids integrate complementary pharmacophores to generate multifunctional scaffolds with broad pharmacological potential. Their structural versatility supports antimicrobial, antifungal, antioxidant, anticancer, anti‐inflammatory, antidiabetic, anticonvulsant, and enzyme‐inhibitory activities.
Subham Kumar Vishwakarma +6 more
wiley +1 more source
Carbonic anhydrase inhibitors and osmotic agents in glaucoma. Carbonic anhydrase inhibitors. [PDF]
openaire +2 more sources
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Design and Synthesis of Bendamustine-Carbonic Anhydrase Inhibitors with Antiproliferative Effects in Clear Cell Renal Cell Carcinoma. [PDF]
Renzi G +6 more
europepmc +1 more source
Toward Ideal Proximity‐Driven Reactions in Chemical Biology
Building on established principles of molecular templation, this perspective explores how molecular recognition can control chemical reactivity in space and time and outlines the design principles of an ideal proximity‐driven reaction for chemical biology.
Dominik Schauenburg
wiley +1 more source
p-Aminobenzene-Sulfonamide Derivatives of Substituted Pyrimidines as Human Carbonic Anhydrase Inhibitors. [PDF]
Angeli A +6 more
europepmc +1 more source

