Results 121 to 130 of about 23,970 (278)
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
Topical carbonic anhydrase inhibitors and visual function in glaucoma and ocular hypertension
, 2010 Dorzolamide and brinzolamide are topical carbonic anhydrase inhibitors (CAI) indicated for patients with glaucoma and ocular ...
Gugleta, Konstantin
core
Pyridazinone substituted benzenesulfonamides as potent carbonic anhydrase inhibitors
, 2016 A series of sulfonamide derivatives (2a-l) incorporating substituted pyridazinone moieties were investigated for the inhibition of two human cytosolic carbonic anhydrase isoforms, hCA I and hCA II.
Samim, Mohammed +8 more
core +1 more source
Insect Molecular Biology, EarlyView.RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour +8 more
wiley +1 more source
CO2‐sensitive K+ channel traffic affects stomata and whole‐plant water use
Journal of Integrative Plant Biology, EarlyView.CO2‐responsive regulation of membrane trafficking influences the density of the potassium ion (K+) channel KAT1 at the plasma membrane. CO2‐sensitive traffic, dependent on trafficking by the SNARE SYP121, impacts stomatal gas exchange and plant growth.
Zhiyi Yu +4 more
wiley +1 more source
, 1989 A Theoretical Study of Conformation-Electronic Structure Relationships in Benzensulfonamide Inhibitors of Carbonic Anhydrase ...
COCCHI, Marina +3 more
core
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Managing prolactin (PRL)‐mediated reproductive suppression is critical for maintaining egg production in commercial laying hens. L‐tyrosine (TYR), a precursor of dopamine (DA), may counteract age‐related reproductive decline by suppressing PRL, thereby sustaining productivity and egg quality in late‐phase laying hens.
Hasan Hüseyin İpçak
wiley +1 more source
, 2017 Dysregulation of noradrenergic and dopaminergic systems is involved in the pathology of attention deficit hyperactivity disorder (ADHD). Carbonic anhydrase (CA) has been reported to affect monoamine transmission in the central nervous system. The aim of
符文美 +1 more
core +1 more source
Role of extracellular carbonic anhydrase in the polar diatom Fragilariopsis cylindrus
New Phytologist, EarlyView.Summary Diatoms are major primary producers in productive polar oceans, where cold temperatures and high CO2 solubility raise questions as to whether they rely on the CO2‐concentrating mechanism (CCM) to saturate photosynthesis. Knowledge of CCM function will help better predict the sensitivity of diatom primary production to warming and acidifying ...
Meng Li, Jodi N. Young
wiley +1 more source
New Phytologist, EarlyView.Schematic representation of the causal sequence through which rapid water loss imposes diffusive and nondiffusive restrictions on carbon assimilation. Summary Drought is an abnormally prolonged water deficit posing major challenges to plants. Stomatal closure has long been considered the primary factor limiting photosynthesis during the early stages of
Chandra Bellasio +4 more
wiley +1 more source