Results 101 to 110 of about 7,272 (219)

Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Here, we report a toxicity study, conducted on zebrafish larvae, of a series of coumarin and sulfamide compounds that were previously reported as inhibitors of human (h) metalloenzymes, carbonic anhydrases (CAs, EC 4.2.1.1).
Ashok Aspatwar, Emanuela Berrino, Silvia Bua, Fabrizio Carta, Clemente Capasso, Seppo Parkkila, Claudiu T. Supuran   +6 more
doaj   +1 more source

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

Food Bioengineering, EarlyView.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang, Ruoke Li, Yixuan Xie, Hanya Zhang, Xiaoyu Huang, Siwei Chen, Weixin Xu, Yueling Liu   +7 more
wiley   +1 more source

Comparison between alpha- and beta-carbonic anhydrases: can Zn(His)3(H2O) and Zn(His)(Cys)2(H2O) sites lead to equivalent enzymes?

, 2011
International audienceLarge models of alpha- and beta-carbonic anhydrases were compared using DFT calculations. They indicate similar acidity of coordinated water molecule and zinc affinity.
Frison, Gilles, Ohanessian, Gilles, Pannetier, Florent   +2 more
core   +4 more sources

Influence of Nanomaterials and Nanocomposites on the Nutrient Composition

Food Safety and Health, EarlyView.
Nanomaterials and nanocomposites enhance crop nutrition and food quality by improving nutrient availability, plant uptake, and bioavailability through controlled delivery and nano‐encapsulation. Their applications in agriculture and food systems enable sustainable biofortification, improved preservation, and functional foods, while emphasizing safety ...
Akanksha Dwivedi, Roohi Yusufi, G. N. Darwhekar, Kuldeep Vinchurkar, Vijay R. Chidrawar   +4 more
wiley   +1 more source

Production and covalent immobilisation of the recombinant bacterial carbonic anhydrase (SspCA) onto magnetic nanoparticles [PDF]

, 2017
Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes with a pivotal potential role in the biomimetic CO2 capture process (CCP) because these biocatalysts catalyse the simple but physiologically crucial reaction of carbon dioxide hydration to ...
Barone, CARMELA MARIA ASSUNTA, Capasso, Clemente, del Prete, Sonia, Perfetto, Rosa, Rossi, Mose, Sansone, Giovanni, Supuran, Claudiu T., Vullo, Daniela   +7 more
core   +1 more source

Optimizing feather hydrolysate via machine learning for microbial recycling of waste concrete fines

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The concrete industry faces significant challenges from CO2 emissions and the disposal of waste concrete fines (WCF). Microbially induced calcite precipitation (MICP) can bind WCF into bioconcrete, but the high cost of commercial culture media hinders its application.
Henrietta Ottová, Barbora Malíková, Václav Nežerka, Petr Holeček, Dana Koňáková, Hana Stiborová   +5 more
wiley   +1 more source

4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases

Molecules, 2014
A series of N-aryl-β-alanine derivatives and diazobenzenesulfonamides containing aliphatic rings were designed, synthesized, and their binding to carbonic anhydrases (CA) I, II, VI, VII, XII, and XIII was studied by the fluorescent thermal shift assay ...
Kęstutis Rutkauskas, Asta Zubrienė, Ingrida Tumosienė, Kristina Kantminienė, Marytė Kažemėkaitė, Alexey Smirnov, Justina Kazokaitė, Vaida Morkūnaitė, Edita Čapkauskaitė, Elena Manakova, Saulius Gražulis, Zigmuntas J. Beresnevičius, Daumantas Matulis   +12 more
doaj   +1 more source

Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures [PDF]

, 2013
Peer ...
Blaesse, Peter, El Muayed, Malek, Helmy, Mohamed, Hennings, J. Christopher, Huebner, Antje K., Hübner, Christian A., Kaila, Kai, Kang, Hyo Jung, Kirilkin, Ilya, Ruusuvuori, Eva, Sestan, Nenad, Voipio, Juha, Yukin, Alexey Y.   +12 more
core   +2 more sources

Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos, Alba Regueira‐Iglesias, Berta Suárez‐Rodríguez, Alba Sánchez‐Barco, Iryna Kuz, Marta Relvas, Susana Belén Bravo, Carlos Balsa‐Castro, Inmaculada Tomás   +8 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source