Results 221 to 230 of about 2,925,002 (305)

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, Volume 13, Issue 53, 24 September 2026.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

Multifaceted Sulfonamide-Derived Thiosemicarbazones: Combining Metal Chelation and Carbonic Anhydrases Inhibition in Anticancer Therapy. [PDF]

Int J Mol Sci
Martínez-Montiel M, Arrighi G, Begines P, González-Bakker A, Puerta A, Fernandes MX, Merino-Montiel P, Montiel-Smith S, Nocentini A, Supuran CT, Padrón JM, Fernández-Bolaños JG, López Ó.   +12 more
europepmc   +1 more source

Combined foliar application of nano‐zinc and nano‐boron improves wheat yield and chlorophyll content under drought stress

Agrosystems, Geosciences &Environment, Volume 9, Issue 3, September 2026.
Abstract Drought stress is a major limiting factor for wheat cultivation in semi‐arid regions, a problem often exacerbated by concurrent soil micronutrient deficiencies. While nanofertilizers can improve nutrient uptake and crop resilience, their specific interactions under defined drought stages are not well documented.
Heidar Abdol Abbas, Ehsan Zeidali, Ali Htami, Mohammad razi Saheb Al‐Asri   +3 more
wiley   +1 more source

Exploring aliphatic sulfonamides as multiclass inhibitors of the carbonic anhydrases from the pathogen bacterium Vibrio cholerae. [PDF]

Arch Pharm (Weinheim)
Paoletti N, Giovannuzzi S, Bonardi A, De Luca V, Capasso C, Nocentini A, Gratteri P, Supuran CT.   +7 more
europepmc   +1 more source

Synthesis and Computational Evaluation of <i>N</i>‑Acetyl-Derived Schiff Bases Incorporating 1,2,4-Triazoles for Dual Inhibition of Prostate Cancer Cells and Carbonic Anhydrases. [PDF]

ACS Omega
Medetalibeyoğlu H, Aytatlı A, Manap S, Atalay A, Ortaakarsu AB, Tüzün B, Taslimi P, Gürsoy-Kol Ö, Karataş ÖF, Yüksek H.   +9 more
europepmc   +1 more source

Plant carbonic anhydrases: structure and mechanism

, 2000
Forsman, C,
core  

Heterologous Expression and Functional Verification of Extracellular Carbonic Anhydrases in Bacillus safensis yw6 from Mariana Trench. [PDF]

Molecules
Wang X, Wang P, Zhao H, He Y, Qu C, Miao J.   +5 more
europepmc   +1 more source

From Identification to Enzymatic Activity Profiling: Comprehensive Characterization of BloCAβ, a Probiotic β‐Carbonic Anhydrase From Bifidobacterium longum

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
Production and biochemical characterization of a new β‐carbonic anhydrase from the probiotic Bifidobacterium longum, one of the main players of human gut microbiota. ABSTRACT The microbiota comprises communities of microorganisms that establish complex relationships with the host and play key roles in physiology, metabolism, and immunity.
Simone Giovannuzzi, Andrea Ammara, Simone Carradori, Viviana De Luca, Marialucia Gallorini, Damiano Iacovozzi, Amelia Cataldi, Ilaria D'Agostino, Davide Moi, Valentina Onnis, Claudiu T. Supuran, Clemente Capasso   +11 more
wiley   +1 more source

Hitting Two Birds With One Stone: Dual Modulation of Brain Carbonic Anhydrases and Histone Deacetylases Boosts Memory Consolidation. [PDF]

Arch Pharm (Weinheim)
Costa A, Bozdag M, Renzi G, Rani B, Passani MB, Angeli A, Provensi G, Carta F, Supuran CT.   +8 more
europepmc   +1 more source

Fragment‐Based Screening of Heterocyclic Electrophiles Identified Acrylamide Bioisoteres for Covalent KRasG12C Inhibitors

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
We screened acrylamide bioisosteres against KRasG12C and prioritized primary hits by their GSH reactivity, labeling efficiency and specificity. The most promising fragment was combined with a KRas‐binding scaffold. Covalent binding, inhibitory activity and selectivity were confirmed via MS, NMR, biochemical and cell viability assays.
Nikolett Péczka, Aaron Keeley, Péter Ábrányi‐Balogh, Zoltán Orgován, László Petri, Emma K. Grant, Chad Quinn, Soma Csanády, Ivan Randelovic, József Tóvári, Jacob Bush, György M. Keserű   +11 more
wiley   +1 more source