Effect of egg turning and incubation time on carbonic anhydrase gene expression in the blastoderm of the Japanese quail (Coturnix c. japonica) [PDF]
, 2008 (1) The gene expression of carbonic anhydrase, a key enzyme for the production sub-embryonic fluid (SEF), was assessed in turned and unturned eggs of the Japanese quail.
Baggott, G. K. +5 more
core +1 more source
Acta Dermato-Venereologica, 2018 Carbonic anhydrases are ubiquitously expressed enzymes that reversibly hydrate carbon dioxide to bicarbonate and protons. While the main function of carbonic anhydrases is to regulate pH and osmotic balance, their involvement in other physiological ...
Bani Kaur Suri +2 more
doaj +1 more source
Exploring the Structural Diversity of Novel 3-Substituted Coumarins as Potent Inhibitors of Tumor-Associated Carbonic Anhydrases: Expanding the Pharmacological Space for Anticancer Drug Discovery [PDF]
, 2023 Innovations in cancer chemotherapy continue to occupy the priority list of demands to ensure our health security. The vast chemical space provides a plethora of anticancer discovery opportunities, however, limited by the boundaries of synthetic ...
Sami, Al-Hussain +5 more
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A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer’s Disease
International Journal of Molecular Sciences, 2019 The increase in the incidence of neurodegenerative diseases, in particular Alzheimer’s Disease (AD), is a consequence of the world′s population aging but unfortunately, existing treatments are only effective at delaying some of the symptoms and for a ...
G. Provensi +6 more
semanticscholar +1 more source
Role of carbon dioxide and ion transport in the formation of sub-embryonic fluid by the blastoderm of the Japanese quail [PDF]
, 2002 1. The explanted blastoderm of the Japanese quail was used to explore the role of ions and carbon dioxide in determining the rate of sub-embryonic fluid (SEF) production between 54 and 72 h of incubation. 2.
Latter, G.V., Baggott, Glenn K.
core +1 more source
Role of carbonic anhydrases in ferroptosis-resistance [PDF]
, 2020 Iron is essential for all the lives on earth but may trigger a switch toward ferroptosis, a novel form of regulated necrosis. Carbonic anhydrases (CAs) are ubiquitous enzymes from microbes to humans. The primary function of CAs is to regulate cellular pH
Li, Zan, Jiang, Li, Toyokuni, Shinya
core +1 more source
Coumarins effectively inhibit bacterial α-carbonic anhydrases
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Coumarins are known to act as prodrug inhibitors of mammalian α-carbonic anhydrases (CAs, EC 4.2.1.1) but they were not yet investigated for the inhibition of bacterial α-CAs.
Simone Giovannuzzi +5 more
doaj +1 more source
Prokaryotic carbonic anhydrases [PDF]
FEMS Microbiology Reviews, 2000 Carbonic anhydrases catalyze the reversible hydration of CO(2) [CO(2)+H(2)Oright harpoon over left harpoon HCO(3)(-)+H(+)]. Since the discovery of this zinc (Zn) metalloenzyme in erythrocytes over 65 years ago, carbonic anhydrase has not only been found in virtually all mammalian tissues but is also abundant in plants and green unicellular algae.
K S, Smith, J G, Ferry
openaire +2 more sources
Targeting carbonic anhydrases in biotechnology
, 2014 Carbonic anhydrases (CAs; EC 4.2.1.1) are ubiquitous metalloenzymes involved in many physiologic processes, such as respiration, CO2 transport , photosynthesis, as well as metabolism of ...
Capasso C., Supuran T.
core +1 more source
Plant Carbonic Anhydrases: Structures, Locations, Evolution, and Physiological Roles
Molecular Plant, 2017 Carbonic anhydrases (CAs) are zinc metalloenzymes that catalyze the interconversion of CO2 and HCO3− and are ubiquitous in nature. Higher plants contain three evolutionarily distinct CA families, αCAs, βCAs, and γCAs, where each family is represented by ...
Robert J. DiMario +4 more
semanticscholar +1 more source