Results 21 to 30 of about 2,875,268 (275)

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Pursuing on our efforts toward searching for efficient hCA IX and hCA XII inhibitors, herein we report the design and synthesis of new sets of benzofuran-based sulphonamides (4a,b, 5a,b, 9a–c, and 10a–d), featuring the zinc anchoring benzenesulfonamide ...
Hadia Almahli   +2 more
exaly   +2 more sources

The role of carbonic anhydrases in extinction of contextual fear memory

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Fabrizio Carta   +2 more
exaly   +2 more sources

Quantitative Characterization of the Chemical Space Governed by Human Carbonic Anhydrases and selenium-containing derivatives of solfonamides [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2022
Due to the fact that different isoforms of carbonic anhydrase play distinct physiological roles, their diseases/disorders involvement are different as well.
Behnam Rasti
doaj   +1 more source

New light on bacterial carbonic anhydrases phylogeny based on the analysis of signal peptide sequences

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2016
Clemente Capasso, Claudiu Supuran
exaly   +2 more sources

Comparison of Carbonic Anhydrases for CO2 Sequestration

open access: yesInternational Journal of Molecular Sciences, 2022
Strategies for depleting carbon dioxide (CO2) from flue gases are urgently needed and carbonic anhydrases (CAs) can contribute to solving this problem. They catalyze the hydration of CO2 in aqueous solutions and therefore capture the CO2.
Franziska Steger   +6 more
semanticscholar   +1 more source

Ureidobenzenesulfonamides as Selective Carbonic Anhydrase I, IX, and XII Inhibitors

open access: yesMolecules, 2023
Sulfonamides remain an important class of drugs, especially because of their inhibitory effects on carbonic anhydrases. Herein, we have synthesized several sulfonamides and tested them for their inhibitory activity against carbonic anhydrases hCA I, hCA ...
Toni C. Denner   +4 more
doaj   +1 more source

Roles of Carbonic Anhydrases and Carbonic Anhydrases Related Proteins in Zebrafish

open access: yesInternational Journal of Molecular Sciences, 2022
During the last decades, zebrafish (Danio rerio) has become one of the most important model organisms to study different physiological and biological phenomena. Research field of carbonic anhydrases (CAs) and carbonic anhydrase related proteins (CARPs) is not an exception in this.
Aspatwar Ashok   +2 more
openaire   +2 more sources

Carbonic anhydrases in fungi [PDF]

open access: yesMicrobiology, 2010
Carbonic anhydrases (CAs) are metalloenzymes that catalyse the interconversion of carbon dioxide and bicarbonate with high efficiency. This reaction is fundamental to biological processes such as respiration, photosynthesis, pH homeostasis, CO2 transport and electrolyte secretion.
Skander, Elleuche, Stefanie, Pöggeler
openaire   +2 more sources

Structural Basis for the Inhibition of Helicobacter pylori α-Carbonic Anhydrase by Sulfonamides. [PDF]

open access: yesPLoS ONE, 2015
Periplasmic α-carbonic anhydrase of Helicobacter pylori (HpαCA), an oncogenic bacterium in the human stomach, is essential for its acclimation to low pH. It catalyses the conversion of carbon dioxide to bicarbonate using Zn(II) as the cofactor.
Joyanta K Modak   +4 more
doaj   +1 more source

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