Results 11 to 20 of about 2,925,002 (305)
Coral Carbonic Anhydrases: Regulation by Ocean Acidification
Marine Drugs, 2016 Global change is a major threat to the oceans, as it implies temperature increase and acidification. Ocean acidification (OA) involving decreasing pH and changes in seawater carbonate chemistry challenges the capacity of corals to form their skeletons ...
Didier Zoccola +5 more
doaj +3 more sources
Thermostable Carbonic Anhydrases in Biotechnological Applications
International Journal of Molecular Sciences, 2015 Carbonic anhydrases are ubiquitous metallo-enzymes which catalyze the reversible hydration of carbon dioxide in bicarbonate ions and protons. Recent years have seen an increasing interest in the utilization of these enzymes in CO2 capture and storage ...
Simona Maria Monti +2 more
exaly +3 more sources
Carbonic Anhydrases: Different Active Sites, Same Metal Selectivity Rules [PDF]
MoleculesCarbonic anhydrases are mononuclear metalloenzymes catalyzing the reversible hydration of carbon dioxide in organisms belonging to all three domains of life.
Nikoleta Kircheva +2 more
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Novel thiazolone-benzenesulphonamide inhibitors of human and bacterial carbonic anhydrases [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 A small library of novel thiazolone-benzenesulphonamides has been prepared and evaluated for their ability to inhibit three human cytosolic carbonic anhydrases (hCA I, hCA II, and hCA VII) and three bacterial carbonic anhydrases (MscCAβ, StCA1, and StCA2)
Morteza Abdoli +4 more
doaj +2 more sources
International Journal of Molecular Sciences, 2019 The genome of Mycobacterium tuberculosis (Mtb) encodes three β-carbonic anhydrases (CAs, EC 4.2.1.1) that are crucial for the life cycle of the bacterium.
Mataleena Parikka +2 more
exaly +2 more sources
Polyamines and α-Carbonic Anhydrases [PDF]
Molecules, 2016 Natural products represent a straightforward source for molecular structures bearing a vast array of chemical features and potentially useful for biomedical purposes.
Andrea Scozzafava +2 more
doaj +3 more sources
Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Six tripeptides incorporating acidic amino acid residues were prepared for investigation as activators of β- and γ-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacteria Vibrio cholerae, Mycobacterium tuberculosis, and Burkholderia ...
Azzurra Stefanucci +8 more
doaj +2 more sources
1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 A series of 1,2,3-benzoxathiazine-2,2-dioxides possessing various substituents in the 5, 7, or 8 position was obtained from corresponding 2-hydroxybenzaldehydes in their reaction with sulfamoyl chloride.
Jekaterina Ivanova +4 more
doaj +2 more sources
Inhibition of pathogenic bacterial carbonic anhydrases by monothiocarbamates [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Carbonic anhydrases (CAs) from the pathogenic bacteria Nesseria gonorrhoeae and vancomycin-resistant enterococci (VRE) have recently been validated as antibacterial drug targets. Here we explored the inhibition of the α-CA from N.
Simone Giovannuzzi +9 more
doaj +2 more sources
Investigation on N-Aryl-2-(4-sulfamoylphenyl)hydrazine-1-carbothioamide as Human Carbonic Anhydrases Inhibitors [PDF]
PharmaceuticalsBackground: Among the 15 human (h) carbonic anhydrase (CA; EC 4.2.1.1) isoforms, hCA IX and XII are particularly important due to their roles in tumor cell growth and survival, identifying them as promising targets for anticancer therapy.
Morteza Abdoli +7 more
doaj +2 more sources