Results 71 to 80 of about 7,272 (219)

Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Six tripeptides incorporating acidic amino acid residues were prepared for investigation as activators of β- and γ-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacteria Vibrio cholerae, Mycobacterium tuberculosis, and Burkholderia ...
Azzurra Stefanucci, Andrea Angeli, Marilisa Pia Dimmito, Grazia Luisi, Sonia Del Prete, Clemente Capasso, William A. Donald, Adriano Mollica, Claudiu T. Supuran   +8 more
doaj   +1 more source

Quantification of carbonic anhydrase gene expression in ventricle of hypertrophic and failing human heart [PDF]

, 2013
Background: Carbonic anhydrase enzymes (CA) catalyze the reversible hydration of carbon dioxide to bicarbonate in mammalian cells. Trans-membrane transport of CA-produced bicarbonate contributes significantly to cellular pH regulation. A body of evidence
Alvarez, Bernardo, Casey, Joseph R., Mullen, John, Quon, Anita L.   +3 more
core   +2 more sources

Improving the 'tool box' for robust industrial enzymes. [PDF]

, 2017
This is the final version of the article. Available from Springer Verlag via the DOI in this record.The speed of sequencing of microbial genomes and metagenomes is providing an ever increasing resource for the identification of new robust biocatalysts ...
Littlechild, JA
core   +1 more source

Experimental Evidence for a Metal‐Related Function of a Cyanobactin

Angewandte Chemie International Edition, EarlyView.
Cyanobactins such as patellamides are produced by cyanobacteria profusely and have been studied extensively, but almost exclusively for their cytotoxic properties. Discussed is unprecedented experimental evidence for a metal‐related biological function – likely CO2 transport from the ascidian to the cyanobacterial symbiont.
Philipp Baur, Timothy A. Hill, Kai‐Chen Wu, Junxian Lim, Brett M. Paterson, Gunasekaran Velmurugan, Bernard M. Degnan, David P. Fairlie, Peter Comba   +8 more
wiley   +1 more source

The Taste of Carbonation [PDF]

, 2009
Carbonated beverages are commonly available and immensely popular, but little is known about the cellular and molecular mechanisms underlying the perception of carbonation in the mouth.
Chandrashekar, Jayaram, Oka, Yuki, Ryba, Nicholas J. P., Sly, William, von Buchholtz, Lars, Yarmolinsky, David, Zuker, Charles S.   +6 more
core   +2 more sources

Technobiological Pathways for High‐CO₂ Capture Using Micro‐/Macroalgae: Genetic Engineering, Process Automation, and Value‐Added Bioproducts

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Greenhouse gas (GHG) emissions have emerged as one of the most critical drivers of climate change; this is primarily due to high concentrations and long atmospheric life of carbon dioxide (CO2). For a significant amount of time, various biological processes such as microalgal cultivation, cyanobacterial systems, photosynthetic microorganisms ...
Sadhana Semwal, Harish Chandra Joshi
wiley   +1 more source

In Silico Assessment of Enaminone–Sulfanilamides as Potential Carbonic Anhydrase II Inhibitors: Molecular Docking and ADMET Prediction

Chemistry Proceedings
Carbonic anhydrases (CAs) are a group of zinc-containing enzymes involved in many physiological processes through their role in the maintenance of the equilibrium between bicarbonate and CO2 levels.
Yousra Ouafa Bouone, Abdeslem Bouzina, Rachida Mansouri, Nour-Eddine Aouf   +3 more
doaj   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

Beyond CO2: Incorporating Bicarbonate, Dynamic Carbon Speciation, and Stoichiometric Plasticity Into Algal Growth Models

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The design of biological carbon capture systems to uptake carbon dioxide by photoautotrophic cultivation of algae has been proposed to mitigate atmospheric carbon emissions. Multiple models to predict algal growth as a function of nutrients have been proposed, but few have delved into the complex dynamic reactions of algal growth as influenced
Elizabeth Flanagan, Caye Drapcho, Mary Katherine Watson   +2 more
wiley   +1 more source

The tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis

BMC Cancer, 2010
Background Medulloblastomas (MBs) and supratentorial primitive neuroectodermal tumours (PNETs) are the most common highly aggressive paediatric brain tumours.
Waheed Abdul, Pastorek Jaromir, Pastorekova Silvia, Laine Jukka, Parkkila Anna-Kaisa, Niemelä Anssi, Korja Miikka, Haapasalo Joonas, Nordfors Kristiina, Sly William S, Parkkila Seppo, Haapasalo Hannu   +11 more
doaj   +1 more source