Results 81 to 90 of about 27,386 (335)

Identification of Bicarbonate as a Trigger and Genes Involved with Extracellular DNA Export in Mycobacterial Biofilms

mBio, 2016
Extracellular DNA (eDNA) is an integral biofilm matrix component of numerous pathogens, including nontuberculous mycobacteria (NTM). Cell lysis is the source of eDNA in certain bacteria, but the source of eDNA remains unidentified for NTM, as well as for
Sasha J. Rose, Luiz E. Bermudez
doaj   +1 more source

Carbonic Anhydrases: An Ancient Tool in Calcareous Sponge Biomineralization

Frontiers in Genetics, 2021
Enzymes of the α-carbonic anhydrase gene family (CAs) are essential for the deposition of calcium carbonate biominerals. In calcareous sponges (phylum Porifera, class Calcarea), specific CAs are involved in the formation of calcite spicules, a unique ...
Oliver Voigt, Benedetta Fradusco, Carolin Gut, Charalampos Kevrekidis, Sergio Vargas, Gert Wörheide, Gert Wörheide, Gert Wörheide   +7 more
doaj   +1 more source

SLC26A Gene Family Participate in pH Regulation during Enamel Maturation. [PDF]

, 2015
The bicarbonate transport activities of Slc26a1, Slc26a6 and Slc26a7 are essential to physiological processes in multiple organs. Although mutations of Slc26a1, Slc26a6 and Slc26a7 have not been linked to any human diseases, disruption of Slc26a1 ...
Kurtz, Ira, Lacruz, Rodrigo S, Lei, Yuejuan, Paine, Michael L, Snead, Malcolm L, Soleimani, Manoocher, Wen, Xin, White, Shane N, Yin, Kaifeng   +8 more
core   +3 more sources

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Six tripeptides incorporating acidic amino acid residues were prepared for investigation as activators of β- and γ-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacteria Vibrio cholerae, Mycobacterium tuberculosis, and Burkholderia ...
Azzurra Stefanucci, Andrea Angeli, Marilisa Pia Dimmito, Grazia Luisi, Sonia Del Prete, Clemente Capasso, William A. Donald, Adriano Mollica, Claudiu T. Supuran   +8 more
doaj   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Cloning, expression and purification of the α-carbonic anhydrase from the mantle of the Mediterranean mussel, Mytilus galloprovincialis [PDF]

, 2017
We cloned, expressed, purified, and determined the kinetic constants of the recombinant α-carbonic anhydrase (rec-MgaCA) identified in the mantle tissue of the bivalve Mediterranean mussel, Mytilus galloprovincialis.
Alasmary, Fatmah A. S., Alothman, Zeid, Barone, Carmela M. A., Capasso, Clemente, Carginale, Vincenzo, Del Prete, Sonia, Osman, Sameh M., Perfetto, Rosa, Rossi, Mosè, Sansone, Giovanni, Supuran, Claudiu T., Vullo, Daniela   +11 more
core   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

The "Click-tail approach" for the design and synthesis of novel carbonic anhydrase inhibitors [PDF]

, 2013
The Carbonic Anhydrases (CAs) are a family of zinc enzymes deputed to the interconversion of carbonic dioxide to hydrogen carbonate. Herein, we report on a sustainable modular strategy, also called "clicktail approach", used to obtain two series of 4-(4 ...
Carta, Fabrizio, Ihm, Simone, McKenna, Robert, Micheletto, Laura, Pala, Nicolino, Sechi, Mario, Supuran, Claudiu T.   +6 more
core  

Mesophyll diffusion conductance to CO 2: An unappreciated central player in photosynthesis [PDF]

, 2012
Mesophyll diffusion conductance to CO 2 is a key photosynthetic trait that has been studied intensively in the past years. The intention of the present review is to update knowledge of g m, and highlight the important unknown and controversial aspects ...
Barbour, Margaret, Brendel, Oliver, Cabrera, Hernan, Carriqui, Marc, Diaz-Espejo, Antonio, Douthe, Cyril, Dreyer, Erwin, Ferrio, Juan-P., Flexas, Jaume, Gago, Jorge, Gallé, Alexander, Galmes, Jeroni, Kodama, Naomi, Medrano, Hippolito, Niinemets, Ülo, Peguero-Pina, Jose-J., Pou, Alicia, Ribas-Carbo, Miquel, Tomas, Magdalena, Tosens, Tina, Warren, Charles-R.   +20 more
core   +2 more sources