Results 61 to 70 of about 69,223 (345)
Energies, 2020 The Hong-Che Fault Zone is one of the important oil and gas enrichment zones in the Junggar Basin, especially in the Carboniferous. In recent five years, it has been proven that the Carboniferous volcanic rock has 140 million tons of oil reserves, and ...
Danping Zhu, Xuewei Liu, Shaobin Guo
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Paleopteran molecular clock: Time drift and recent acceleration
Ecology and EvolutionApplying BEAST v1.10.4, we constructed a Bayesian Inference tree comprising 322 taxa, primarily representing Paleoptera (Odonata and Ephemeroptera; Pterygota), Zygentoma and Archaeognatha (Apterygota; paraphyly), and Neoptera (Plecoptera; Pterygota ...
Soichi Osozawa, André Nel
doaj +1 more source
Energy Science & Engineering, 2020 In view of the complex reservoir heterogeneities within weathered volcanic rocks, taking the Carboniferous volcanic weathered profile reservoir of the northwest Junggar Basin as an example, this study aims to characterize weathered volcanic rocks by the ...
Cunhui Fan +5 more
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Unravelling the relative contributions of climate change and ground disturbance to subsurface temperature perturbations: Case studies from Tyneside, UK [PDF]
, 2016 When assessing subsurface urban heat islands (UHIs) it is important to distinguish between localized effects of land-use change and the impacts of global climate change. However, few investigations have successfully unraveled the two influences.
Westaway, Rob, Younger, Paul L.
core +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
DiversityBonebeds occurring in exposures of the Burlington and Keokuk Limestones (Mississippian/Osagean) along the Iowa and Illinois border (USA) contain an abundant and diverse collection of chondrichthyan remains that includes teeth, spines, denticles, and ...
David Cicimurri +7 more
doaj +1 more source
New basal Odonatoptera (Insecta) from the lower Carboniferous (Serpukhovian) of Argentina [PDF]
, 2016 Nuevos Odonatoptera basales del Serpukhoviano superior (325-324 Ma) son descriptos de la localidad Guandacol 1, Quebrada de las Libélulas, Formación Guandacol, provincia de La Rioja, centro oeste de la Argentina.
Gutierrez, Pedro Raul +1 more
core
Tectonic overview of the West Gondwana margin [PDF]
, 2008 The oceanic southern margin of Gondwana, from southern South America through South Africa, West Antarctica, New Zealand (in its pre break-up position), and Victoria Land to Eastern Australia is one of the longest and longest-lived active continental ...
Pankhurst, Robert J., Vaughan, Alan P.M.
core +1 more source
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source