Results 61 to 70 of about 14,849 (185)

Larvicidal activity of Melissa officinalis and Rosmarinus officinalis extracts and its lethal impacts on detoxifying enzymes in larvae of Aedes aegypti L. [PDF]

open access: yesJournal of Advanced Biomedical Sciences
Background & Objectives: Mosquito-borne diseases significantly impact global health, particularly in tropical regions. While synthetic insecticides are currently employed to control mosquito vectors, their detrimental effects on ecosystems and ...
Mohd Abass Sofi   +7 more
doaj  

Chronotherapy in Hematological Malignancies: Evaluating the Rationale and Evidence

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Hematological malignancies remain one of the leading causes of morbidity and mortality despite advances in targeted therapies, immunotherapy, and stem cell transplantation. Emerging evidence indicates that treatment efficacy and toxicity depend not only on the choice of therapy but also on its timing relative to the patient's internal ...
Andrej Belančić   +7 more
wiley   +1 more source

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

open access: yesThe FEBS Journal, Volume 293, Issue 15, Page 4724-4743, August 2026.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova   +6 more
wiley   +1 more source

Regulation of the rat neutral cytosolic cholesteryl ester hydrolase promoter by hormones and sterols: a role for nuclear factor-Y in the sterol-mediated response

open access: yesJournal of Lipid Research, 1999
Expression of the rat liver neutral cytosolic cholesteryl ester hydrolase (CEH) gene is regulated by glucocorticoids, thyroxine, and agents that perturb cholesterol metabolism.
Ramesh Natarajan   +2 more
doaj   +1 more source

Dual-Purpose Inoculants and Their Effects on Corn Silage

open access: yesMicroorganisms, 2020
This study was conducted to screen dual-purpose lactic acid bacteria (LAB) from uncontrolled farm-scale silage, and then we confirmed their effects on corn silage.
Dimas Hand Vidya Paradhipta   +7 more
doaj   +1 more source

Influence of N‐Functionalization of Amiridine on the Biological Activity of Its Conjugates as Multitarget Agents for Potential Treatment of Alzheimer's Disease

open access: yesChemMedChem, Volume 21, Issue 14, 29 July 2026.
New conjugates of amiridine and salicylimine/amine with an N‐acylalkylene spacer were synthesized. N‐acylation of amiridine conjugates leads to a decrease in their protonation, resulting in a substantial reduction in anticholinesterase activity and relative inability to block Aβ42 self‐aggregation compared to previously studied analogs with an N ...
Galina F. Makhaeva   +14 more
wiley   +1 more source

Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells

open access: yesMolecules, 2018
Herb-drug interactions are important safety concerns in clinical practice. The interactions occur firstly in the intestinal absorption for orally administered drugs.
Zongxi Sun   +7 more
doaj   +1 more source

Carboxylesterases in lipid metabolism: from mouse to human

open access: yesProtein & Cell, 2017
Mammalian carboxylesterases hydrolyze a wide range of xenobiotic and endogenous compounds, including lipid esters. Physiological functions of carboxylesterases in lipid metabolism and energy homeostasis in vivo have been demonstrated by genetic ...
Jihong Lian   +2 more
doaj   +1 more source

Genome-Wide Identification and Functional Analysis of Carboxylesterase and Methylesterase Gene Families in Peach (Prunus persica L. Batsch)

open access: yesFrontiers in Plant Science, 2019
Carboxylesterases (CXE) and methylesterases (MES) are hydrolytic enzymes that act on carboxylic esters and are involved in plant metabolic processes and defense responses.
Xiangmei Cao   +6 more
doaj   +1 more source

Identification and biochemical characterization of a carboxylesterase gene associated with β-cypermethrin resistance in Dermanyssus gallinae

open access: yesPoultry Science
: Dermanyssus gallinae is a major hematophagous ectoparasite in layer hens. Although the acaricide β-cypermethrin has been used to control mites worldwide, D. gallinae has developed resistance to this compound.
Xuedi Zhang   +6 more
doaj   +1 more source

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