Results 61 to 70 of about 17,229 (228)
Targeting Carboxylesterase 2 Activity for Predicting and Improving Response to Pancreatic Cancer Treatment [PDF]
, 2023 Pancreatic ductal adenocarcinoma is an aggressive form of cancer, with low patient survival rates. Irinotecan, a key chemotherapeutic drug, is activated by carboxylesterase 2, which has been established as a predictive and prognostic biomarker of patient
Kailass, Karishma
core
Journal of Insect Science, 2004 The inhibition kinetics of dichlorvos on carboxylesterase and acetylcholinesterase (AChE) activity extracted from Liposcelis bostrychophila and L. entomophila (Psocoptera: Liposcelididae) were compared. The results showed that L.
Jin-Jun Wang, Wei-Xia Cheng, Zhi-Mo Zhao
doaj
ELECTROPHORESIS, EarlyView.Inhibition assays in in‐capillary continuous enzymatic reaction were simulated using a MATLAB matrix. The enzymatic hydrolysis of p‐nitrophenyl phosphate (S) with alkaline phosphatase (ALP) was adopted as a model enzymatic reaction, where theophylline (I) was used as a model inhibitor.
Toshio Takayanagi +2 more
wiley +1 more source
Acyl-Coenzyme A:Cholesterol O -Acyltransferase Is Not Identical to Liver Microsomal Carboxylesterase [PDF]
, 1996 Acyl-coenzyme A (CoA):cholesterol O -acyltransferase (ACAT) is responsible for esterification of cholesterol in the cell. The enzyme has never been purified, but two cDNA sequences coding for this enzyme were recently reported ...
Ingemar Björkhem +3 more
core +1 more source
Microorganisms, 2021 The present study aimed to investigate effects of dual-purpose inoculants (antifungal and carboxylesterase activities) not only on corn silage quality, but also its shelf life against mold contamination at feed-out phase.
Dimas Hand Vidya Paradhipta +8 more
doaj +1 more source
iMetaOmics, EarlyView.An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda +8 more
wiley +1 more source
Identification of resistant carboxylesterase alleles in
, 2012 Background Carboxylesterase overproduction is a frequently observed resistance mechanism of insects to organophosphate insecticides. As a major transmitter of human diseases, mosquitoes in the Culex pipiens complex have evolved 13 carboxylesterase ...
Zhang Hanying +3 more
core +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Poultry Science: Dermanyssus gallinae is a major hematophagous ectoparasite in layer hens. Although the acaricide β-cypermethrin has been used to control mites worldwide, D. gallinae has developed resistance to this compound.
Xuedi Zhang +6 more
doaj +1 more source
Toxins, 2022 Gossypol is a polyphenolic toxic secondary metabolite derived from cotton. Free gossypol in cotton meal is remarkably harmful to animals. Furthermore, microbial degradation of gossypol produces metabolites that reduce feed quality.
Li Zhang +6 more
doaj +1 more source