Results 101 to 110 of about 15,347 (200)
A highly selective ratiometric fluorescent probe for invitro monitoring and cellular imaging of human carboxylesterase
冯磊 +7 more
core
Carboxylesterase 1 - Structure and endogenous functions
Carboxylesterases are an important class of enzymes that are mainly known to participate in thedetoxification and metabolism of drugs and environmental toxicants.
Korup, Ida Møller +2 more
core
Gemcitabine (dFdC) demonstrates significant effectiveness against solid tumors in vitro and in vivo; however, its clinical application is limited because it tends to easily undergo deamination metabolism.
Yilin Sun, Jiankun Wang, Kun Hao
doaj +1 more source
This study employed an integrated multi‐omics screening strategy incorporating GEO database differential expression analysis, GWAS‐eQTL genetic association analysis, and single‐cell RNA‐seq cell subpopulation localization to identify EPHX2 as a core causal gene in ulcerative colitis (UC).
Tian Dai +8 more
wiley +1 more source
Characterization of carboxylesterases involved in the insecticide resistance of Culex quinquefasciatus from the Caribbean and South America. [PDF]
The organophosphate resistance-associated elevated esterases Estα2, Estβ1 and Estβ2 were purified to homogeneity from larvae of the Cuban Habana strain.
Small, Graham John
core +1 more source
The reactions of 3,3,3-trifluoro-2,2-dihydroxy-1-phenyl-1-propanone (TDPP) with chicken liver carboxylesterase have shown that this ketone hydrate is not only a potent inhibitor of the enzyme, but also a substrate for a number of enzyme-catalyzed ...
King G.J. +3 more
core +1 more source
Defined Nylon Oligomers Enable Mechanistic Insight Into Enzymatic Polyamide Depolymerization
The remarkable progress in enzymatic polyester depolymerization has demonstrated the potential of biocatalysis for sustainable polymer recycling. In contrast, enzymatic polyamide (PA) degradation remains poorly understood, largely due to the lack of defined and accessible model substrates.
Sukmanita Dewi +3 more
wiley +1 more source
Carboxylesterase activities are widely distributed in a great variety of tissues; however, the biological function of these enzymes remains unclear. Some organophosphorus compounds induce a neurodegenarative syndrome related to the covalent modification ...
Sogorb, Miguel A. +3 more
core +1 more source
Characterization of a Murine cDNA Encoding a Member of the Carboxylesterase Multigene Family
We have characterized a mRNA sequence containing the entire coding region of a mouse carboxylesterase (EC 3.1.1.1). pEs-N, an 1840-bp composite of five overlapping cDNA clones, contains an open reading frame of 554 amino acids that display a high degree ...
S. Medda +13 more
core +1 more source
The targeted delivery of therapeutics to the tumor site is highly desirable in cancer treatment, because it is capable of minimizing collateral damage.
Hongwang Wang +14 more
doaj +1 more source

