Results 111 to 120 of about 27,172,362 (207)

Carboxylesterase 1 (CES1; hCE1) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants [PDF]

, 1997
Boven, E., Giaccone, G., Hulscher, S.T.M., Jansen, W.J.M., Pinedo, H.M., Zwart, B.   +5 more
core   +1 more source

Impact Of Using Long Lasting Insecticidal Treated Nets (LLIN) And Indoor Residual Spraying (IRS), Single And In Combination On Insecticide Resistant Anopheles Arabiensis Patton (Diptera: Culicidae) In Republic Of The Sudan [PDF]

, 2017
Pengawalan vektor malaria di Sudan bergantung kepada penggunaan kelambu yang diimpregnasikan dengan insektisid yang tahan lama (LLINs) dan penyemburan residu dalam rumah (IRS) di kawasan perumahan Malaria vector control in Sudan depends on the ...
Mohammed Ahmed, Bashir Adam Ismail
core  

Clinical pharmacokinetics and metabolism of irinotecan (CPT-11) [PDF]

, 2001
CPT-11 belongs to the class of topoisomerase I inhibitors, and it acts as a prodrug of SN-38, which is approximately 100-1000-fold more cytotoxic than the parent drug.
Alphen, R.J. (Robbert) van, Loos, W.J. (Walter), Mathijssen, A.H.J. (Ron), Nooter, K. (Kees), Sparreboom, A. (Alex), Stoter, G. (Gerrit), Verweij, J. (Jaap)   +6 more
core  

A dysregulation in CES1, APOE and other lipid metabolism-related genes is associated to cardiovascular risk factors linked to obesity [PDF]

, 2010
OBJECTIVE: The aim of the present study was to investigate the relationship between the differential expression of genes related to lipid metabolism in subcutaneous adipose tissue and metabolic syndrome features in lean and obese subjects with ...
Gonzalez-Muniesa, P. (Pedro), Marrades, M.P. (María Pilar), Martinez, J.A. (José Alfredo), Moreno-Aliaga, M. J. (María Jesús)   +3 more
core  

Confounding Effect of Hepatic Carboxylesterase 1 (CES1) Variability on Clopidogrel Oxidation. [PDF]

Mol Pharm
Subash S, Singh DK, Khojasteh SC, Murray BP, Zientek MA, Jones RS, Kulkarni P, Smith BJ, Prasad B.   +8 more
europepmc   +1 more source

Ester Prodrug NLRP3 Inflammasome Inhibitor NT-0796 is Brain Active due to Activation by Local Expression of Carboxylesterase-1. [PDF]

ACS Chem Neurosci
Digby Z, Diamond C, Wescott H, Smolak P, Thornton P, Lindsay N, Gabel CA, Clarke N, Watt AP.   +8 more
europepmc   +1 more source

An in vitro evaluation of common botanical extracts on carboxylesterase 1 catalytic activity. [PDF]

Drug Metab Dispos
Melchert PW, Zhang Q, Raeuscher JM, Gurley BJ, Markowitz JS.   +4 more
europepmc   +1 more source

Randomized evaluation of the loss-of-function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics. [PDF]

Clin Transl Sci
Lewis JP, Ryan KA, Streeten EA, Whitlatch HB, Daue M, Tanner K, Perry JA, O'Connell JR, Shuldiner AR, Mitchell BD.   +9 more
europepmc   +1 more source

Increased serum carboxylesterase-1 levels are associated with metabolic dysfunction associated steatotic liver disease and metabolic syndrome in children with obesity. [PDF]

Ital J Pediatr
Wang H, Wu S, Weng Y, Yang X, Hou L, Liang Y, Wu W, Ying Y, Ye F, Luo X.   +9 more
europepmc   +1 more source