Microbial Cell Factories / Pichia pastoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion [PDF]
, 2014 Background: The methylotrophic yeast Pichia pastoris is frequently used for the production of recombinant proteins. However, expression levels can vary depending on the target protein.
Buchetics, Markus +7 more
core +5 more sources
Equine recurrent uveitis - A spontaneous horse model of uveitis [PDF]
, 2008 Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis.
Altmann, Frank +8 more
core +1 more source
Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis. [PDF]
, 2015 BackgroundAlthough much is known about the mechanism of action of Bacillus thuringiensis Cry toxins, the target tissue cellular responses to toxin activity is less understood.
Bravo, Alejandra +4 more
core +1 more source
Cannabinoid Inhibition of Carboxylesterase 1 (CES1)
The FASEB Journal, 2019 The increasing use of cannabis for both medical indications and on a recreational basis poses a potential for drug interactions between cannabis or one or more of its constituents and conventional therapeutic agents. Although significant efforts have been made to assess the in vitro and
Yuli Qian, John S. Markowitz
openaire +1 more source
Occurrence of target-site resistance to neonicotinoids in the aphid Myzus persicae in Tunisia, and its status on different host plants [PDF]
, 2018 This is the peer reviewed version of the following article: Kamel Charaabi, Sonia Boukhris-bouhachem, Mohamed Makni, and Ian Denholm, ‘Occurrence of target‐site resistance to neonicotinoids in the aphid Myzus persicae in Tunisia, and its status on ...
Bass +28 more
core +2 more sources
Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1. [PDF]
PLoS One, 2015 Human Carboxylesterase 1 (hCES1) is the key liver microsomal enzyme responsible for detoxification and metabolism of a variety of clinical drugs. To analyse the role of the single N-linked glycan on the structure and activity of the enzyme, authentically
Arena de Souza V +6 more
europepmc +4 more sources
Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles [PDF]
Biotechnology Progress, 2011 AbstractThe encapsulation of proteins in biomimetic silica has recently been shown to successfully maintain enzymes in their active state. Organophosphate (OP) compounds are used as pesticides as well as potent chemical warfare nerve agents. Because these toxicants are life threatening, we sought to generate biomimetic silicas capable of responding to ...
Jonathan S, Edwards +6 more
openaire +2 more sources
An extracellular carboxylesterase from the basidiomycete Pleurotus sapidus hydrolyses xanthophyll esters [PDF]
, 2005 An extracellular enzyme capable of efficient hydrolysis of xanthophyll esters was purified from culture supernatants of the basidiomycete Pleurotus sapidus.
Berger, Ralf Günter +6 more
core +1 more source
Purification of a chymotrypsin-like enzyme present on adult Schistosoma mansoni worms from infected mice and its characterization as a host carboxylesterase [PDF]
, 2016 A serine protease-like enzyme found in detergent extracts of Schistosoma mansoni adult worms perfused from infected mice has been purified from mouse blood and further characterized.
Doenhoff, Michael J. +3 more
core +2 more sources
Biotechnological applications of functional metagenomics in the food and pharmaceutical industries [PDF]
, 2015 peer-reviewedMicroorganisms are found throughout nature, thriving in a vast range of environmental conditions. The majority of them are unculturable or difficult to culture by traditional methods.
Alvarez-Ordonez, Avelino +3 more
core +1 more source