Results 61 to 70 of about 15,347 (200)

Cannabinoid Inhibition of Carboxylesterase 1 (CES1)

The FASEB Journal, 2019
The increasing use of cannabis for both medical indications and on a recreational basis poses a potential for drug interactions between cannabis or one or more of its constituents and conventional therapeutic agents. Although significant efforts have been made to assess the in vitro and
Yuli Qian, John S. Markowitz
openaire   +1 more source

cDNA cloning and characterization of the carboxylesterase pxCCE016b from the diamondback moth, Plutella xylostella L.

Journal of Integrative Agriculture, 2016
Carboxylesterase is a multifunctional superfamily and can be found in almost all living organisms. As the metabolic enzymes, carboxylesterases are involved in insecticides resistance in insects for long time.
Zhen-di HU, Xia FENG, Qing-sheng LIN, Huan-yu CHEN, Zhen-yu LI, Fei YIN, Pei LIANG, Xi-wu GAO   +7 more
doaj   +1 more source

Accurate Assessment and Tracking the Process of Liver-Specific Injury by the Residual Tissue Activity of Carboxylesterase 1 and Dipeptidyl Peptidase 4

Engineering, 2022
Accurately assessing and tracking the progression of liver-specific injury remains a major challenge in the field of biomarker research. Here, we took a retrospective validation approach built on the mutuality between serum and tissue biomarkers to ...
Qiusha Pan, Peifang Song, Zhenhua Ni, Xingkai Qian, Anqi Wang, Liwei Zou, Yong Liu, Ping Wang, Weidong Zhang, Hong Ma, Ling Yang   +10 more
doaj   +1 more source

Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms. [PDF]

Basic Clin Pharmacol Toxicol, 2016
AbstractOseltamivir, an inactive anti‐influenza virus prodrug, is activated (hydrolysed) in vivo by carboxylesterase 1 (CES1) to its active metabolite oseltamivir carboxylate. CES1 functions are significantly associated with certain CES1 genetic variants and some non‐genetic factors. The purpose of this study was to investigate the effect of gender and
Shi J, Wang X, Eyler RF, Liang Y, Liu L, Mueller BA, Zhu HJ.   +6 more
europepmc   +5 more sources

Effects of Inoculants Producing Antifungal and Carboxylesterase Activities on Corn Silage and Its Shelf Life against Mold Contamination at Feed-Out Phase

Microorganisms, 2021
The present study aimed to investigate effects of dual-purpose inoculants (antifungal and carboxylesterase activities) not only on corn silage quality, but also its shelf life against mold contamination at feed-out phase.
Dimas Hand Vidya Paradhipta, Young Ho Joo, Hyuk Jun Lee, Seong Shin Lee, Hyeon Tak Noh, Jeong Seok Choi, Jinwoo Kim, Hyeong Gyu Min, Sam Churl Kim   +8 more
doaj   +1 more source

Dataset of gene cloning and gel filtration chromatography of R-est6

Data in Brief, 2016
The data presented in this article are connected to the research article entitled “Expression, purification and biochemical characterization of a family 6 carboxylesterase from Methylococcus capsulatus (bath)” (Soni et al., 2016 [1]).
Surabhi Soni, Annamma A. Odaneth, Arvind M. Lali, Sanjeev K. Chandrayan   +3 more
doaj   +1 more source

Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity

Journal of Lipid Research, 2004
Paraoxonase-1 (PON1) is known to be associated with high density lipoproteins. We optimized buffer conditions to obtain quantitative recovery of PON1 (arylesterase) activity and analyzed the distribution of PON1 in mice using a combination of size ...
Philip W. Connelly, Graham F. Maguire, Dragomir I. Draganov   +2 more
doaj   +1 more source

Biochemical biomarkers in nile tilapias (Oreochromis niloticus Linnaeus, 1758) of different weights exposed to contaminants

Revista de Biologia Neotropical, 2020
Nile tilapias (Oreochromis niloticus) of three groups with different weights (juvenile, adults of lower and higher weight) were exposed to benzo[a]pyrene (0.5 mg.L-1), cupper (0.5 mg.L-1), cadmium (0.5 mg.L-1) and diazinon (1.0 mg.L-1), for 72 h.
Daniele Silva, Lenard Serrano, Eduardo Alves de Almeida   +2 more
doaj   +1 more source

Biomarkers in rock oysters (Saccostrea mordax) in response to organophosphate pesticides

Ilmu Kelautan, 2021
Chlorpyrifos is a xenobiotics contaminants that threats the marine environment and the living organism within the habitat. Although several marine bivalve species have been used as the indicator of marine pollution, the used of Saccostrea mordax is ...
Kennedy Opiyo, Christopher Rawson, Marthe Monique Gagnon, Ishaaq Saputra   +3 more
doaj   +1 more source

Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway. [PDF]

Mol Pharm, 2018
Carboxylesterase-1 (CE-1) is a crucial enzyme responsible for metabolism/activation/inactivation of xenobiotics (therapeutic agents, prodrugs, abused drugs, and organophosphorus nerve agents etc.) and also involved in many other biological processes.
Yao J, Chen X, Zheng F, Zhan CG.
europepmc   +2 more sources