Inhibition of carboxymethyllysine in walnut cookies via food additives [PDF]
Food Chemistry: XCarboxymethyllysine(CML) is one of advanced glycation end products(AGEs), which is associated with the occurrence and development of chronic diseases such as diabetes, cardiovascular disease, Alzheimer's disease, etc.
Wenfeng Han +3 more
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Carboxymethyllysine and carboxyethyllysine in multiple sclerosis patients
Archives of Medical Science, 2020 Introduction Advanced glycation end-products (AGE) are involved in the pathogenesis of many diseases, including neurodegenerative diseases such as multiple sclerosis (MS).
Aleksandra Damasiewicz-Bodzek +3 more
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Phosphorylated Alpha-Synuclein and Carboxymethyllysine in the Epidermis of Type 2 Diabetes Patients: Preliminary Observations [PDF]
BiomedicinesBackground/objectives: Alpha-synuclein (aSyn) is best known for its role in Parkinson’s disease. Increasing evidence suggests a bidirectional relationship between diabetes mellitus and synuclein pathology. Carboxymethyllysine (CML), an advanced glycation
Bernard Kordas +3 more
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CIGB-258, a Potential Novel Approach to Treat Sepsis-like Hyperinflammation, Reduces Gastrointestinal Hemorrhage in Zebrafish Exposed to Carboxymethyllysine and Ethanol [PDF]
PharmaceuticalsObjective: CIGB-258 is a 3 KDa altered peptide ligand recognized for its anti-inflammatory activity. Herein, the effect of CIGB-258 was assessed against carboxymethyllysine (CML) and ethanol (Et-OH)-induced sepsis-like events in zebrafish (Danio rerio ...
Kyung-Hyun Cho +5 more
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Controlled Formation of Carboxymethyllysine in Bone Matrix through Designed Glycation Reaction [PDF]
JBMR Plus, 2021 It has been a challenge to establish a link between specific advanced glycation end products (AGEs) as causal agents of different pathologies and age‐related diseases, primarily because of the lack of suitable in vitro experimental strategies ...
Grażyna E. Sroga, Deepak Vashishth
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Dietary N‐epsilon‐carboxymethyllysine as for a major glycotoxin in foods: A review [PDF]
Comprehensive Reviews in Food Science and Food Safety, 2021 Abstract N‐epsilon‐carboxymethyllysine (CML), as a potential glycotoxin and general marker for dietary advanced glycation end products (dAGEs), exists in raw food and is formed via various formation routes in food processing such as Maillard reaction between the reducing sugars and amino acids.
Gengjun Chen
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Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis [PDF]
Journal of Neuroinflammation, 2010 Background This study compared the level of advanced glycation end products (AGEs), N-(Carboxymethyl)lysine (CML) and N-(Carboxyethyl)lysine (CEL), in patients with multiple sclerosis (MS) and healthy controls (HCs), correlating these markers with ...
Weinstock-Guttmann Bianca +7 more
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Advanced glycation end-products and sclerostin are elevated across diabetes phenotypes and associated with vertebral fractures in type 2 diabetes [PDF]
BMC Endocrine DisordersBackground To investigate the associations of circulating advanced glycation end-products (AGEs; carboxymethyllysine and pentosidine) and sclerostin with bone mineral density (BMD) and vertebral fractures in adults with type 1 diabetes mellitus (T1DM ...
Sevdenur Taskin Kursun +2 more
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Serum carboxymethyllysine concentration is associated with erosive hand osteoarthritis
Osteoarthritis and Cartilage, 2023 Carboxymethyllysine (CML) and homocitrulline (HCit) are the products of two non-enzymatic post-translational modifications of protein, a process related to age. We investigated whether serum CML and HCit concentrations were associated with hand osteoarthritis (HOA), especially erosive HOA.Serum CML and HCit were measured by using liquid chromatography ...
Adeline Cambon-Binder +2 more
exaly +3 more sources
Diabetic nephropathy patients show hyper-responsiveness to N6-carboxymethyllysine
Brazilian Journal of Medical and Biological Research, 2022 The aim of this study was to evaluate the impact of N6-carboxymethyllysine (CML) on NF-κB gene expression and tumor necrosis factor (TNF) production in diabetic nephropathy. This was an observational study comprised of three groups: diabetic nephropathy (
C.G. Dias +2 more
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