Results 31 to 40 of about 1,999 (189)

Glycation of N-ε-carboxymethyllysine [PDF]

open access: yesEuropean Food Research and Technology, 2021
AbstractThe Maillard reaction is traditionally subdivided into three stages that start consecutively and run in parallel. Here, we show that N-ε-carboxymethyllysine (CML), a compound formed in the late stage of the reaction, can undergo a second glycation event at its secondary amino group leading to a new class of Amadori rearrangement products.
Michael Hellwig   +2 more
openaire   +1 more source

Ozonated Sunflower Oil Exerted Potent Anti-Inflammatory Activities with Enhanced Wound Healing and Tissue Regeneration Abilities against Acute Toxicity of Carboxymethyllysine in Zebrafish with Improved Blood Lipid Profile

open access: yesAntioxidants, 2023
Ozonated sunflower oil (OSO) is an established therapeutic agent and nutraceutical harboring various therapeutic values, including antiallergic, derma-protective, and broad-spectrum antimicrobial activity.
Kyung-Hyun Cho   +3 more
doaj   +1 more source

Comprehensive Quantification of Carboxymethyllysine-Modified Peptides in Human Plasma

open access: yesJournal of the American Society for Mass Spectrometry, 2021
A prolonged hyperglycemic condition in diabetes mellitus results in glycation of plasma proteins. N(ε)-Carboxymethyllysine (CML) is a well-known protein advanced glycation end product, and one of its mechanisms of formation is through further oxidation of Amadori compound modified lysine (AML). Unlike enrichment of AML peptides using boronate affinity,
Arvind M. Korwar, Qibin Zhang
openaire   +4 more sources

Formation of advanced glycation end products in raw and subsequently boiled broiler muscle: biological variation and effects of postmortem ageing and storage

open access: yesFood Science and Human Wellness, 2022
The study aimed to investigate and compare the contents of carboxymethyllysine (CML) in two kinds of broilers during postmortem ageing and storage. The contents of CML in raw and boiled (100 °C, 30 min) broiler briskets and legs which were from white ...
Suhong Huang   +6 more
doaj   +1 more source

Bioactivity of selected materials for coffee substitute. [PDF]

open access: yesPLoS ONE, 2018
Epidemiological studies have suggested that coffee consumption is negatively correlated with the incidence of Parkinson's disease. Coffee contains relatively high levels of β-carbolines, which have been ascribed neuroactive effects in humans however the ...
Renata Zawirska-Wojtasiak   +4 more
doaj   +1 more source

Dataset for Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N(6)-Carboxymethyllysine

open access: yes, 2022
Microglial function declines during aging. The interaction of microglia with the gut microbiota has been well characterized during development and adulthood, but not in aging.
Omar Mossad (11990199)   +2 more
core   +1 more source

Heat-Induced Toxicants: Sensory Appeal Distracts Consumers' Attention From Potential Toxicological Risks of Thermally Processed Foods. [PDF]

open access: yesFood Sci Nutr
The central paradox of thermal processing of foods. (A) The application of heat (e.g., frying, baking, grilling) to food initiates complex chemical reactions, most notably the Maillard reaction and thermal degradation of protein, lipids, and carbohydrate. (B) These reactions create a desirable sensory experience characterized by enticing aromas, golden‐
Matondo JD, Issa-Zacharia A.
europepmc   +2 more sources

Inter- and Intraindividual Differences in the Capacity of the Human Intestinal Microbiome in Fecal Slurries to Metabolize Fructoselysine and Carboxymethyllysine

open access: yes, 2022
The advanced glycation endproduct carboxymethyllysine and its precursor fructoselysine are present in heated, processed food products and are considered potentially hazardous for human health.
Karsten Beekmann (1409260)   +4 more
core   +1 more source

Multitargeted Modulation of Skin Dullness by HNHT Formulation: Synergistic Inhibition of Melanogenesis, Glycation, and Lipofuscin Deposition. [PDF]

open access: yesJ Cosmet Dermatol
ABSTRACT Background Skin dullness, characterized by pigmentation disorders and yellowing, is a major cosmetic concern in Asian populations. Lipofuscin exhibits ultraviolet (UV)/visible light spectral absorption, reduces skin reflectance, and contributes to dullness, whereas existing therapies targeting melanogenesis and glycation lack comprehensive ...
Wang Z, Fan Y, Ling P.
europepmc   +2 more sources

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