Results 21 to 30 of about 93,784 (226)

Proteases Shape the Chlamydomonas Secretome: Comparison to Classical Neuropeptide Processing Machinery

Proteomes, 2018
The recent identification of catalytically active peptidylglycine α-amidating monooxygenase (PAM) in Chlamydomonas reinhardtii, a unicellular green alga, suggested the presence of a PAM-like gene and peptidergic signaling in the last eukaryotic ...
Raj Luxmi, Crysten Blaby-Haas, Dhivya Kumar, Navin Rauniyar, Stephen M. King, Richard E. Mains, Betty A. Eipper   +6 more
doaj   +1 more source

High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma

Molecules, 2020
Proteomic technologies have identified 234 peptidases in plasma but little quantitative information about the proteolytic activity has been uncovered.
Elisa Maffioli, Zhenze Jiang, Simona Nonnis, Armando Negri, Valentina Romeo, Christopher B. Lietz, Vivian Hook, Giuseppe Ristagno, Giuseppe Baselli, Erik B. Kistler, Federico Aletti, Anthony J. O’Donoghue, Gabriella Tedeschi   +12 more
doaj   +1 more source

CPB1 of Aedes aegypti Interacts with DENV2 E Protein and Regulates Intracellular Viral Accumulation and Release from Midgut Cells

Viruses, 2014
Aedes aegypti is a principal vector responsible for the transmission of dengue viruses (DENV). To date, vector control remains the key option for dengue disease management.
Hong-Wai Tham, Vinod R. M. T. Balasubramaniam, Bimo Ario Tejo, Hamdan Ahmad, Sharifah Syed Hassan   +4 more
doaj   +1 more source

Nerve injury evoked loss of latexin expression in spinal cord neurons contributes to the development of neuropathic pain. [PDF]

PLoS ONE, 2011
Nerve injury leads to sensitization mechanisms in the peripheral and central nervous system which involve transcriptional and post-transcriptional modifications in sensory nerves.
Hilmar Nils Kühlein, Irmgard Tegeder, Christine Möser, Hee-Young Lim, Annett Häussler, Katharina Spieth, Ingo Jennes, Rolf Marschalek, Tobias Beckhaus, Michael Karas, Markus Fauth, Corina Ehnert, Gerd Geisslinger, Ellen Niederberger   +13 more
doaj   +1 more source

Metallopeptidases of Toxoplasma gondii: in silico identification and gene expression

Parasite, 2018
Metallopeptidases are a family of proteins with domains that remain highly conserved throughout evolution. These hydrolases require divalent metal cation(s) to activate the water molecule in order to carry out their catalytic action on peptide bonds by ...
Escotte-Binet Sandie, Huguenin Antoine, Aubert Dominique, Martin Anne-Pascaline, Kaltenbach Matthieu, Florent Isabelle, Villena Isabelle   +6 more
doaj   +1 more source

Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]

, 2014
The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita, Barroso, Booz, Bosnyak, Bosnyak, Brosnihan, Bruneval, Bryan, Calo, Campbell, Caroline Fattah, Castro, Chappell, Chappell, Chen, Christopher M. Loughrey, Clare A. McKinney, Clarke, Costa, Crackower, Cushman, De Mello, Dias-Peixoto, Domeier, Dong, Donoghue, Donoghue, Drummer, Faria-Silva, Ferreira, Ferreira, Ferreira, Ferreira, Flores-Munoz, Flores-Munoz, Fomovsky, Fraga-Silva, Fraga-Silva, Freeman, Galis, Gava, Gembardt, Gomes, Graeme Milligan, Grobe, Gusev, Hanke, Hannan, Harmer, Heitsch, Horiguchi, Horiuchi, Hunyady, Inaba, Iwata, Jackman, Jaiswal, Jarajapu, Kaminska, Kassiri, Katada, Kokkonen, Kramkowski, Langeveld, Lautner, Liao, Libby, Liu, Loot, Lovren, Masson, McCollum, Mehta, Mercure, Miura, Mogielnicki, Nakajima, Newby, Ng, Nouet, Ocaranza, Ocaranza, Ocaranza, Patel, Patel, Qi, Ray, Rice, Rodgers, Rodrigues-Machado, Ross, Rowe, Sampaio, Sampaio, Santos, Santos, Schultz Jel, Selvetella, Shah, Sheng-Long, Singh, Sluimer, Stegbauer, Strawn, Stuart A. Nicklin, Tallant, Tesanovic, Tipnis, Turner, Uekama, Varagic, Vickers, Vilas-Boas, Walters, Wang, Weber, West, Wiemer, Yamada, Yang, Zeng, Zhang, Zhao, Zhong   +123 more
core   +1 more source

Characterization, Recombinant Production and Structure-Function Analysis of NvCI, A Picomolar Metallocarboxypeptidase Inhibitor from the Marine Snail Nerita versicolor

Marine Drugs, 2019
A very powerful proteinaceous inhibitor of metallocarboxypeptidases has been isolated from the marine snail Nerita versicolor and characterized in depth.
Giovanni Covaleda-Cortés, Martha Hernández, Sebastián Alejandro Trejo, Manuel Mansur, Sergi Rodríguez-Calado, Javier García-Pardo, Julia Lorenzo, Josep Vendrell, María Ángeles Chávez, Maday Alonso-del-Rivero, Francesc Xavier Avilés   +10 more
doaj   +1 more source

Impact of Different Storage Temperature on the Enzymatic Activity of Apis mellifera Royal Jelly

Foods, 2022
Royal Jelly is a nutrient secretion of nurse bees and a high interest functional food in human nutrition. Very little information is available on its chemical composition integrity and enzymatic activity during shelf life and assessment of new freshness ...
Simona Sagona, Francesca Coppola, Gino Giannaccini, Laura Betti, Lionella Palego, Elena Tafi, Lucia Casini, Lucia Piana, Raffaele Dall’Olio, Antonio Felicioli   +9 more
doaj   +1 more source

Expression of recombinant mouse cytosolic carboxypeptidase 6 in Escherichia coli [PDF]

E3S Web of Conferences, 2020
Cytosolic carboxypeptidase 6 (CCP6) is a member of cytosolic carboxypeptidase (CCP) family that catalyze the removal of polyglutamate side chains from protein substrates.
Wang Ruixue, Wu Hui-Yuan
doaj   +1 more source

Degrading Ochratoxin A and Zearalenone Mycotoxins Using a Multifunctional Recombinant Enzyme

Toxins, 2019
Zearalenone (ZEA) is an estrogenic and ochratoxin A (OTA) is a hepatotoxic Fusarium mycotoxin commonly seen in cereals and fruits products. No previous investigation has studied on a single platform for the multi degradation mycotoxin.
Md Shofiul Azam, Dianzhen Yu, Na Liu, Aibo Wu   +3 more
doaj   +1 more source